Interactor	Canonical Name	Naming Convention	Major Loc With Loc Score	Minor Loc	Loc Experimental System Type	Loc Source DB	Interaction Source DB	Taxonomy ID
P00374	Dihydrofolate reductase	UniProtKB/Swiss-Prot/P	N/A(0.3)|Cytosol(0.3)|Mitochondrion(0.96)|Nucleus(0.7)	GO:0005575|GO:0005829|GO:0005739|GO:0005739|GO:0005634	Unknown: no biological data available|Unknown: traceable author statement|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Predicted: SVM decision tree	GO|GO|GO|The Human Protein Atlas|eSLDB		9606
P10809	60 kDa heat shock protein, mitochondrial	UniProtKB/Swiss-Prot/P	Membrane(0.999)|Cytosol(1)|Mitochondrion(1)|Nucleus(0.96)|Secretory-pathway(0.988)|Extracellular(0.992)	GO:0009986|GO:0005905|GO:0005737|GO:0005737|GO:0005737|GO:0005829|GO:0005739|GO:0005739|GO:0005739|GO:0005739|GO:0005739|GO:0005759|GO:0005743|GO:0032991|GO:0019907|GO:0005769|GO:0030141|GO:0030135|GO:0005576|GO:0005615|GO:0031012|GO:0016020|GO:0016020|GO:0046696|GO:0005886|GO:0070062	Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: experimental|Predicted: PAML algorithm|Experimental: inferred from direct assay|Predicted: SVM decision tree|Experimental: inferred from direct assay|Experimental: experimental|Predicted: PAML algorithm|Experimental: annotated protein expression (APE)|Unknown: traceable author statement|Predicted: inferred from sequence or structural similarity|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Predicted: inferred from sequence or structural similarity|Experimental: inferred from direct assay|Experimental: experimental|Experimental: inferred from direct assay|Experimental: experimental|Unknown: HDA|Experimental: experimental|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Unknown: HDA	GO|GO|GO|Human Proteinpedia|PA-GOSUB|GO|eSLDB|GO|Organelle|PA-GOSUB|The Human Protein Atlas|GO|GO|GO|GO|GO|GO|GO|MatrixDB|GO|MatrixDB|GO|MatrixDB|GO|GO|GO	HPRD|BioGRID	9606
O95831	Apoptosis-inducing factor 1, mitochondrial	UniProtKB/Swiss-Prot/P	Cytosol(0.79)|Mitochondrion(0.998)|Nucleus(0.996)|Extracellular(0.8)|Membrane(0.8)	GO:0005829|GO:0048471|GO:0005739|GO:0005739|GO:0005739|GO:0005739|GO:0005758|GO:0005743|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0005576|GO:0016020	Predicted: inferred from sequence or structural similarity|Unknown: inferred from electronic annotation|Predicted: SVM decision tree|Unknown: HDA|Experimental: experimental|Predicted: PAML algorithm|Experimental: inferred from direct assay|Unknown: traceable author statement|Experimental: experimental|Predicted: inferred from sequence or structural similarity|Predicted: pTarget method|Experimental: experimental|Experimental: experimental|Experimental: experimental	GO|GO|eSLDB|GO|Organelle|PA-GOSUB|GO|GO|eSLDB|GO|LOCATE|Organelle|MatrixDB|eSLDB	IntAct	9606
Q8IWL3	Iron-sulfur cluster co-chaperone protein HscB, mitochondrial	UniProtKB/Swiss-Prot/P	Cytosol(0.992)|Mitochondrion(0.998)|Nucleus(0.96)	GO:0005737|GO:0005829|GO:0005829|GO:0005739|GO:0005739|GO:0005739|GO:0005739|GO:0005634|GO:0005634	Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: experimental|Experimental: inferred from direct assay|Predicted: PAML algorithm|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)	GO|GO|The Human Protein Atlas|eSLDB|GO|PA-GOSUB|The Human Protein Atlas|GO|The Human Protein Atlas	IntAct	9606
P04637	Cellular tumor antigen p53	UniProtKB/Swiss-Prot/P	Cytosol(0.998)|Mitochondrion(0.972)|Nucleus(1)|Secretory-pathway(0.3)	GO:0005622|GO:0005737|GO:0005737|GO:0005829|GO:0005739|GO:0005739|GO:0005759|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0005730|GO:0016363|GO:0005654|GO:0005654|GO:0016604|GO:0016605|GO:0005669|GO:0032991|GO:0005783|GO:0000790|GO:0005657	Experimental: inferred from direct assay|Experimental: experimental|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: experimental|Unknown: inferred from electronic annotation|Predicted: SVM decision tree|Experimental: inferred from direct assay|Predicted: pTarget method|Experimental: experimental|Predicted: PAML algorithm|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: inferred from mutant phenotype|Unknown: inferred from electronic annotation|Experimental: inferred from direct assay|Predicted: inferred from biological aspect of ancestor	GO|eSLDB|GO|GO|GO|Organelle|GO|eSLDB|GO|LOCATE|Organelle|PA-GOSUB|GO|GO|GO|The Human Protein Atlas|GO|GO|GO|GO|GO|GO|GO	BioGRID	9606
Q15388	Mitochondrial import receptor subunit TOM20 homolog	UniProtKB/Swiss-Prot/P	Mitochondrion(1)|Extracellular(0.96)|Membrane(0.8)	GO:0005739|GO:0005739|GO:0005739|GO:0005739|GO:0005739|GO:0005739|GO:0005739|GO:0005741|GO:0005742|GO:0031307|GO:0005576|GO:0031012|GO:0016021	Experimental: experimental|Experimental: inferred from direct assay|Experimental: experimental|Predicted: pTarget method|Experimental: experimental|Predicted: PAML algorithm|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Unknown: traceable author statement|Predicted: inferred from biological aspect of ancestor|Experimental: experimental|Experimental: experimental|Experimental: experimental	eSLDB|GO|Human Proteinpedia|LOCATE|Organelle|PA-GOSUB|The Human Protein Atlas|GO|GO|GO|MatrixDB|MatrixDB|eSLDB	HPRD	9606
Q99853	Forkhead box protein B1	UniProtKB/Swiss-Prot/P	Mitochondrion(0.8)|Nucleus(0.998)	GO:0005739|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0005654	Experimental: annotated protein expression (APE)|Predicted: SVM decision tree|Predicted: inferred from sequence or structural similarity|Predicted: pTarget method|Predicted: PAML algorithm|Experimental: annotated protein expression (APE)	The Human Protein Atlas|eSLDB|GO|LOCATE|PA-GOSUB|The Human Protein Atlas	IntAct|BioGRID	9606
P0CG48	Polyubiquitin-C	UniProtKB/Swiss-Prot/P	Membrane(0.902)|Cytosol(0.969)|Mitochondrion(0.3)|Nucleus(0.956)|Secretory-pathway(0.657)|Extracellular(0.902)	GO:0043209|GO:0005737|GO:0005737|GO:0005829|GO:0005741|GO:0005634|GO:0005634|GO:0005634|GO:0005654|GO:0005789|GO:0010008|GO:0030666|GO:0005576|GO:0043657|GO:0005615|GO:0016020|GO:0005886|GO:0031982|GO:0070062	Unknown: inferred from electronic annotation|Predicted: SVM decision tree|Predicted: pTarget method|Unknown: traceable author statement|Unknown: traceable author statement|Predicted: SVM decision tree|Unknown: HDA|Predicted: PAML algorithm|Unknown: traceable author statement|Unknown: traceable author statement|Unknown: traceable author statement|Unknown: traceable author statement|Experimental: experimental|Unknown: inferred from electronic annotation|Unknown: HDA|Experimental: experimental|Unknown: traceable author statement|Unknown: HDA|Unknown: HDA	GO|eSLDB|LOCATE|GO|GO|eSLDB|GO|PA-GOSUB|GO|GO|GO|GO|MatrixDB|GO|GO|MatrixDB|GO|GO|GO	BioGRID	9606
Q14258	E3 ubiquitin/ISG15 ligase TRIM25	UniProtKB/Swiss-Prot/P	Cytosol(0.988)|Nucleus(1)	GO:0005737|GO:0005829|GO:0005829|GO:0005634|GO:0005634|GO:0005654|GO:0005654|GO:0016604|GO:0016604	Predicted: PAML algorithm|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Predicted: SVM decision tree|Predicted: PAML algorithm|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)	PA-GOSUB|GO|The Human Protein Atlas|eSLDB|PA-GOSUB|GO|The Human Protein Atlas|GO|The Human Protein Atlas	BioGRID	9606
Q00987	E3 ubiquitin-protein ligase Mdm2	UniProtKB/Swiss-Prot/P	Cytosol(0.972)|Nucleus(1)|Secretory-pathway(0.3)|Membrane(0.51)	GO:0005737|GO:0005737|GO:0005829|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0005730|GO:0005654|GO:0016604|GO:0032991|GO:0030666|GO:0005886|GO:0045202	Experimental: experimental|Experimental: inferred from mutant phenotype|Unknown: traceable author statement|Experimental: experimental|Experimental: inferred from direct assay|Predicted: pTarget method|Experimental: experimental|Predicted: PAML algorithm|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: inferred from mutant phenotype|Unknown: traceable author statement|Unknown: traceable author statement|Unknown: inferred from electronic annotation	eSLDB|GO|GO|eSLDB|GO|LOCATE|Organelle|PA-GOSUB|The Human Protein Atlas|GO|GO|GO|GO|GO|GO|GO	BioGRID|HPRD	9606
P00533	Epidermal growth factor receptor	UniProtKB/Swiss-Prot/P	Secretory-pathway(0.999)|Membrane(1)|Cytosol(0.972)|Nucleus(0.994)|Extracellular(0.86)	GO:secretory_pathway|GO:0009986|GO:0012505|GO:0005737|GO:0048471|GO:0005634|GO:0005634|GO:0031965|GO:0032991|GO:0005789|GO:0000139|GO:0005768|GO:0031901|GO:0010008|GO:0030665|GO:0005576|GO:0005615|GO:0016020|GO:0016020|GO:0016021|GO:0016021|GO:0045121|GO:0030122|GO:0005886|GO:0005886|GO:0005886|GO:0005886|GO:0070435|GO:0043235|GO:0016324|GO:0016323|GO:0005925|GO:0045202	Predicted: SVM decision tree|Experimental: inferred from direct assay|Experimental: experimental|Experimental: inferred from direct assay|Unknown: inferred from electronic annotation|Experimental: inferred from direct assay|Experimental: experimental|Unknown: inferred from electronic annotation|Experimental: inferred from direct assay|Unknown: inferred from electronic annotation|Unknown: inferred from electronic annotation|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Unknown: traceable author statement|Experimental: experimental|Unknown: non-traceable author statement|Experimental: inferred from direct assay|Experimental: experimental|Experimental: experimental|Unknown: inferred from electronic annotation|Experimental: inferred from direct assay|Unknown: traceable author statement|Experimental: inferred from direct assay|Predicted: pTarget method|Experimental: experimental|Experimental: annotated protein expression (APE)|Predicted: inferred from sequence or structural similarity|Experimental: inferred from direct assay|Unknown: inferred from electronic annotation|Experimental: inferred from direct assay|Unknown: HDA|Unknown: inferred from electronic annotation	eSLDB|GO|Organelle|GO|GO|GO|Organelle|GO|GO|GO|GO|GO|GO|GO|GO|MatrixDB|GO|GO|MatrixDB|eSLDB|GO|GO|GO|GO|LOCATE|Organelle|The Human Protein Atlas|GO|GO|GO|GO|GO|GO	BioGRID	9606
Q5VSY0	G kinase-anchoring protein 1	UniProtKB/Swiss-Prot/P	Cytosol(0.988)|Mitochondrion(0.7)|Secretory-pathway(0.91)	GO:0005737|GO:0005829|GO:0005739|GO:0005794|GO:0005794|GO:0005815	Predicted: PAML algorithm|Experimental: annotated protein expression (APE)|Predicted: SVM decision tree|Predicted: inferred from sequence or structural similarity|Predicted: PAML algorithm|Experimental: annotated protein expression (APE)	PA-GOSUB|The Human Protein Atlas|eSLDB|GO|PA-GOSUB|The Human Protein Atlas	BioGRID	9606
Q53GA5	Cellular tumor antigen p53	UniProtKB/TrEmbl/P	Cytosol(0.8)|Nucleus(0.94)	GO:0005737|GO:0005634|GO:0005634	Experimental: experimental|Experimental: experimental|Predicted: pTarget method	eSLDB|eSLDB|LOCATE	HPRD|BioGRID	9606
G3XA89	E3 ubiquitin-protein ligase Mdm2	UniProtKB/TrEmbl/P	Cytosol(0.7)|Nucleus(0.94)	GO:0005737|GO:0005634|GO:0005634	Predicted: SVM decision tree|Predicted: pTarget method|Experimental: annotated protein expression (APE)	eSLDB|LOCATE|The Human Protein Atlas	BioGRID	9606
Q9UKV5	E3 ubiquitin-protein ligase AMFR	UniProtKB/Swiss-Prot/P	Cytosol(0.992)|Nucleus(0.86)|Secretory-pathway(1)|Membrane(0.952)|Extracellular(0.8)	GO:0012505|GO:0043025|GO:0005737|GO:0048471|GO:0005634|GO:0032991|GO:0005783|GO:0005783|GO:0005783|GO:0005783|GO:0005783|GO:0005789|GO:0030176|GO:0030176|GO:0044322|GO:0005794|GO:0005794|GO:0030426|GO:0030425|GO:0005576|GO:0016020|GO:0016021|GO:0016021	Experimental: experimental|Unknown: inferred from electronic annotation|Predicted: SVM decision tree|Experimental: inferred from direct assay|Unknown: inferred from electronic annotation|Experimental: inferred from direct assay|Experimental: experimental|Experimental: inferred from direct assay|Experimental: experimental|Predicted: PAML algorithm|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: experimental|Unknown: inferred from electronic annotation|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Unknown: inferred from electronic annotation|Unknown: inferred from electronic annotation|Experimental: experimental|Unknown: HDA|Experimental: experimental|Unknown: non-traceable author statement	Organelle|GO|eSLDB|GO|GO|GO|eSLDB|GO|Organelle|PA-GOSUB|The Human Protein Atlas|GO|GO|Organelle|GO|GO|The Human Protein Atlas|GO|GO|MatrixDB|GO|eSLDB|GO	BioGRID	9606
Q12952	Forkhead box protein L1	UniProtKB/Swiss-Prot/P	Nucleus(0.996)	GO:0005634|GO:0005634|GO:0005634|GO:0005634	Experimental: experimental|Predicted: inferred from biological aspect of ancestor|Experimental: experimental|Predicted: PAML algorithm	eSLDB|GO|Organelle|PA-GOSUB	BioGRID|IntAct	9606
P07996	Thrombospondin-1	UniProtKB/Swiss-Prot/P	Secretory-pathway(0.998)|Membrane(0.998)|Cytosol(0.992)|Nucleus(0.8)|Extracellular(0.996)	GO:secretory_pathway|GO:0009986|GO:0005737|GO:0016529|GO:0005634|GO:0005783|GO:0005788|GO:0030141|GO:0031091|GO:0031093|GO:0005856|GO:0005576|GO:0005576|GO:0005615|GO:0005577|GO:0031012|GO:0031012|GO:0016020|GO:0005886|GO:0009897|GO:0070062	Predicted: SVM decision tree|Experimental: inferred from direct assay|Experimental: experimental|Predicted: inferred from sequence or structural similarity|Experimental: experimental|Predicted: inferred from sequence or structural similarity|Unknown: traceable author statement|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Unknown: traceable author statement|Experimental: experimental|Unknown: HDA|Predicted: PAML algorithm|Unknown: HDA|Experimental: inferred from direct assay|Unknown: HDA|Experimental: experimental|Experimental: experimental|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Unknown: HDA	eSLDB|GO|Human Proteinpedia|GO|Human Proteinpedia|GO|GO|GO|GO|GO|Human Proteinpedia|GO|PA-GOSUB|GO|GO|GO|MatrixDB|MatrixDB|The Human Protein Atlas|GO|GO	HPRD	9606
Q498Y4	Forkhead box L1	UniProtKB/TrEmbl/P	Nucleus(0.8)	GO:0005634	Experimental: experimental	eSLDB	BioGRID	9606
A0A087X1Q1	Cellular tumor antigen p53	UniProtKB/TrEmbl/P	Nucleus(0.8)	GO:0005654	Experimental: annotated protein expression (APE)	The Human Protein Atlas	BioGRID	9606
A0A087WXZ1	Cellular tumor antigen p53	UniProtKB/TrEmbl/P	Nucleus(0.8)	GO:0005654	Experimental: annotated protein expression (APE)	The Human Protein Atlas	BioGRID	9606
A0A087WT22	Cellular tumor antigen p53	UniProtKB/TrEmbl/P	Nucleus(0.8)	GO:0005654	Experimental: annotated protein expression (APE)	The Human Protein Atlas	BioGRID	9606
A7UKX8	E3 ubiquitin-protein ligase Mdm2	UniProtKB/TrEmbl/P	Nucleus(0.8)	GO:0005634	Experimental: annotated protein expression (APE)	The Human Protein Atlas	BioGRID	9606
Q96DS0	MDM2 variant FB55	UniProtKB/TrEmbl/P	Nucleus(0.7)	GO:0005634	Predicted: PAML algorithm	PA-GOSUB	BioGRID	9606
P62942	Peptidyl-prolyl cis-trans isomerase FKBP1A	UniProtKB/Swiss-Prot/P	Cytosol(1)|Secretory-pathway(0.7)|Membrane(0.86)|Extracellular(0.8)	GO:0005737|GO:0005737|GO:0005737|GO:0016529|GO:0005829|GO:0014802|GO:0030018|GO:0043679|GO:0005576|GO:0016020	Predicted: SVM decision tree|Experimental: inferred from direct assay|Predicted: PAML algorithm|Predicted: inferred from sequence or structural similarity|Experimental: inferred from direct assay|Predicted: inferred from sequence or structural similarity|Experimental: inferred from direct assay|Unknown: inferred from electronic annotation|Experimental: experimental|Experimental: inferred from direct assay	eSLDB|GO|PA-GOSUB|GO|GO|GO|GO|GO|MatrixDB|GO	HPRD|BioGRID	9606
Q0VDC6	Peptidylprolyl isomerase	UniProtKB/TrEmbl/P	Cytosol(0.7)	GO:0005737	Predicted: SVM decision tree	eSLDB	BioGRID	9606
F2YGG7	Receptor protein-tyrosine kinase	UniProtKB/TrEmbl/P	Extracellular(0.8)	GO:0005576	Experimental: experimental	MatrixDB	BioGRID	9606
Q504U8	Receptor protein-tyrosine kinase	UniProtKB/TrEmbl/P	Extracellular(0.8)|Membrane(0.8)	GO:0005576|GO:0005886	Experimental: experimental|Experimental: annotated protein expression (APE)	MatrixDB|The Human Protein Atlas	BioGRID	9606
Q6FGQ5	ASGR1 protein	UniProtKB/TrEmbl/P	Membrane(0.7)	GO:0016021	Predicted: SVM decision tree	eSLDB	HPRD	9606
E9PFD7	Receptor protein-tyrosine kinase	UniProtKB/TrEmbl/P	Extracellular(0.8)|Membrane(0.8)	GO:0005576|GO:0005886	Experimental: experimental|Experimental: annotated protein expression (APE)	MatrixDB|The Human Protein Atlas	BioGRID	9606
E7BSV0	Receptor protein-tyrosine kinase	UniProtKB/TrEmbl/P	Extracellular(0.8)	GO:0005576	Experimental: experimental	MatrixDB	BioGRID	9606
B7Z2I3	Receptor protein-tyrosine kinase	UniProtKB/TrEmbl/P	Extracellular(0.8)	GO:0005576	Experimental: experimental	MatrixDB	BioGRID	9606