Interactor	Canonical Name	Naming Convention	Major Loc With Loc Score	Minor Loc	Loc Experimental System Type	Loc Source DB	Interaction Source DB	Taxonomy ID
Q8N2H9	E3 ubiquitin-protein ligase pellino homolog 3	UniProtKB/Swiss-Prot/P	Cytosol(0.958)|Nucleus(0.996)	GO:0005737|GO:0005829|GO:0043231|GO:0005634|GO:0005634|GO:0005634|GO:0005730	Predicted: SVM decision tree|Unknown: traceable author statement|Experimental: annotated protein expression (APE)|Predicted: SVM decision tree|Predicted: pTarget method|Experimental: annotated protein expression (APE)|Experimental: annotated protein expression (APE)	eSLDB|GO|The Human Protein Atlas|eSLDB|LOCATE|The Human Protein Atlas|The Human Protein Atlas		9606
Q13404	Ubiquitin-conjugating enzyme E2 variant 1	UniProtKB/Swiss-Prot/P	Cytosol(1)|Nucleus(1)|Membrane(0.94)	GO:0000151|GO:0005737|GO:0005737|GO:0005829|GO:0031371|GO:0035370|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0005654|GO:0005654|GO:0032991|GO:0016020|GO:0016021|GO:0070062	Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: experimental|Unknown: traceable author statement|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Predicted: SVM decision tree|Unknown: traceable author statement|Experimental: experimental|Predicted: PAML algorithm|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Experimental: experimental|Predicted: SVM decision tree|Unknown: HDA	GO|GO|Human Proteinpedia|GO|GO|GO|eSLDB|GO|Organelle|PA-GOSUB|GO|The Human Protein Atlas|GO|eSLDB|eSLDB|GO	BioGRID	9606
Q99558	Mitogen-activated protein kinase kinase kinase 14	UniProtKB/Swiss-Prot/P	Cytosol(1)|Nucleus(1)	GO:0005737|GO:0005737|GO:0005829|GO:0005829|GO:0043231|GO:0043231|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0001650|GO:0001650	Predicted: inferred from biological aspect of ancestor|Predicted: PAML algorithm|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Predicted: SVM decision tree|Experimental: inferred from direct assay|Predicted: pTarget method|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)	GO|PA-GOSUB|GO|The Human Protein Atlas|GO|The Human Protein Atlas|eSLDB|GO|LOCATE|The Human Protein Atlas|GO|The Human Protein Atlas	BioGRID|HPRD|IntAct	9606
P61088	Ubiquitin-conjugating enzyme E2 N	UniProtKB/Swiss-Prot/P	Cytosol(1)|Nucleus(1)	GO:0000151|GO:0005737|GO:0005737|GO:0005737|GO:0005737|GO:0005829|GO:0031372|GO:0035370|GO:0005634|GO:0005634|GO:0001650|GO:0001650|GO:0005654|GO:0032991|GO:0070062	Experimental: inferred from direct assay|Predicted: SVM decision tree|Unknown: traceable author statement|Experimental: experimental|Predicted: PAML algorithm|Unknown: traceable author statement|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Unknown: traceable author statement|Experimental: inferred from direct assay|Unknown: HDA	GO|eSLDB|GO|Human Proteinpedia|PA-GOSUB|GO|GO|GO|GO|The Human Protein Atlas|GO|The Human Protein Atlas|GO|GO|GO	BioGRID	9606
Q9UNE7	E3 ubiquitin-protein ligase CHIP	UniProtKB/Swiss-Prot/P	Cytosol(1)|Nucleus(0.998)|Secretory-pathway(0.8)	GO:0000151|GO:0005737|GO:0005737|GO:0005737|GO:0005829|GO:0005829|GO:0031371|GO:0005634|GO:0042405|GO:0005654|GO:0005654|GO:0005783|GO:0030018	Experimental: inferred from direct assay|Experimental: experimental|Predicted: inferred from sequence or structural similarity|Predicted: PAML algorithm|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Unknown: traceable author statement|Predicted: inferred from sequence or structural similarity|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Unknown: inferred from electronic annotation	GO|eSLDB|GO|PA-GOSUB|GO|The Human Protein Atlas|GO|GO|GO|GO|The Human Protein Atlas|GO|GO	BioGRID	9606
O43318	Mitogen-activated protein kinase kinase kinase 7	UniProtKB/Swiss-Prot/P	Cytosol(0.987)|Nucleus(0.997)|Secretory-pathway(0.3)|Extracellular(0.8)|Membrane(0.3)	GO:0005737|GO:0005829|GO:0005829|GO:0008385|GO:0005634|GO:0005634|GO:0005634|GO:0016607|GO:0005671|GO:0010008|GO:0005576|GO:0005886	Predicted: PAML algorithm|Unknown: traceable author statement|Experimental: annotated protein expression (APE)|Predicted: inferred from physical interaction|Predicted: SVM decision tree|Unknown: HDA|Predicted: pTarget method|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Unknown: traceable author statement|Experimental: experimental|Unknown: inferred from electronic annotation	PA-GOSUB|GO|The Human Protein Atlas|GO|eSLDB|GO|LOCATE|The Human Protein Atlas|GO|GO|MatrixDB|GO	HPRD|IntAct|BioGRID	9606
Q9Y4K3	TNF receptor-associated factor 6	UniProtKB/Swiss-Prot/P	Cytosol(0.999)|Mitochondrion(0.8)|Nucleus(0.992)|Secretory-pathway(0.3)|Extracellular(0.7)|Membrane(0.982)	GO:0005737|GO:0005737|GO:0005737|GO:0005811|GO:0005829|GO:0048471|GO:0005938|GO:0005739|GO:0005634|GO:0005730|GO:0032991|GO:0010008|GO:0005576|GO:0005886|GO:0009898|GO:0035631	Predicted: SVM decision tree|Experimental: inferred from direct assay|Predicted: PAML algorithm|Predicted: inferred from sequence or structural similarity|Unknown: traceable author statement|Experimental: inferred from direct assay|Unknown: inferred from electronic annotation|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Unknown: traceable author statement|Predicted: pTarget method|Experimental: inferred from direct assay|Predicted: inferred from sequence or structural similarity|Predicted: inferred from sequence or structural similarity	eSLDB|GO|PA-GOSUB|GO|GO|GO|GO|The Human Protein Atlas|GO|The Human Protein Atlas|GO|GO|LOCATE|GO|GO|GO	HPRD|BioGRID|IntAct	9606
P51617	Interleukin-1 receptor-associated kinase 1	UniProtKB/Swiss-Prot/P	Cytosol(0.999)|Mitochondrion(0.8)|Nucleus(0.988)|Secretory-pathway(0.3)|Membrane(0.902)	GO:0005737|GO:0005737|GO:0005811|GO:0005829|GO:0005829|GO:0005739|GO:0005634|GO:0005634|GO:0005634|GO:0010008|GO:0005886|GO:0005886|GO:0045323	Predicted: inferred from biological aspect of ancestor|Predicted: PAML algorithm|Predicted: inferred from sequence or structural similarity|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: experimental|Predicted: SVM decision tree|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Unknown: traceable author statement|Unknown: traceable author statement|Experimental: experimental|Unknown: non-traceable author statement	GO|PA-GOSUB|GO|GO|The Human Protein Atlas|Human Proteinpedia|eSLDB|GO|The Human Protein Atlas|GO|GO|Organelle|GO	IntAct|DIP|BioGRID|HPRD	9606
Q9UDY4	DnaJ homolog subfamily B member 4	UniProtKB/Swiss-Prot/P	Cytosol(0.96)|Nucleus(0.988)|Secretory-pathway(0.7)|Extracellular(0.8)|Membrane(0.96)	GO:0005829|GO:0005829|GO:0005634|GO:0005654|GO:0005654|GO:0005783|GO:0005576|GO:0005886|GO:0005886	Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Predicted: SVM decision tree|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Predicted: PAML algorithm|Experimental: experimental|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)	GO|The Human Protein Atlas|eSLDB|GO|The Human Protein Atlas|PA-GOSUB|MatrixDB|GO|The Human Protein Atlas	BioGRID	9606
P05067	Amyloid-beta A4 protein	UniProtKB/Swiss-Prot/P	Secretory-pathway(1)|Membrane(1)|Cytosol(1)|Nucleus(0.96)|Extracellular(0.98)	GO:secretory_pathway|GO:0009986|GO:0005905|GO:0045177|GO:0005737|GO:0005737|GO:0005829|GO:0048471|GO:0043231|GO:0005634|GO:0005641|GO:0005783|GO:0005791|GO:0005790|GO:0005788|GO:0005794|GO:0005794|GO:0005794|GO:0005796|GO:0032588|GO:0005768|GO:0005768|GO:0031904|GO:0005764|GO:0031093|GO:0030134|GO:0051233|GO:0097449|GO:0043198|GO:0043197|GO:0030424|GO:0044304|GO:0035253|GO:0005576|GO:0005576|GO:0005576|GO:0005615|GO:0016020|GO:0016021|GO:0016021|GO:0045121|GO:0005886|GO:0005886|GO:0005886|GO:0005887|GO:0043235|GO:0031982|GO:0070062|GO:0005911|GO:0045202|GO:0031594|GO:0048786	Experimental: experimental|Experimental: inferred from direct assay|Unknown: inferred from electronic annotation|Unknown: inferred from electronic annotation|Experimental: experimental|Predicted: inferred from sequence or structural similarity|Unknown: traceable author statement|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: experimental|Experimental: inferred from direct assay|Experimental: experimental|Unknown: inferred from electronic annotation|Unknown: inferred from electronic annotation|Unknown: traceable author statement|Experimental: experimental|Predicted: inferred from sequence or structural similarity|Experimental: annotated protein expression (APE)|Unknown: traceable author statement|Unknown: traceable author statement|Experimental: experimental|Experimental: inferred from direct assay|Unknown: traceable author statement|Experimental: experimental|Unknown: traceable author statement|Unknown: inferred from electronic annotation|Unknown: inferred from electronic annotation|Unknown: inferred from electronic annotation|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Predicted: inferred from sequence or structural similarity|Unknown: inferred from electronic annotation|Unknown: inferred from electronic annotation|Experimental: experimental|Unknown: traceable author statement|Experimental: experimental|Unknown: HDA|Experimental: experimental|Predicted: SVM decision tree|Predicted: inferred from sequence or structural similarity|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Predicted: pTarget method|Experimental: experimental|Unknown: traceable author statement|Experimental: inferred from direct assay|Experimental: experimental|Unknown: HDA|Unknown: inferred from electronic annotation|Experimental: inferred from direct assay|Unknown: inferred from electronic annotation|Unknown: inferred from electronic annotation	eSLDB|GO|GO|GO|eSLDB|GO|GO|GO|The Human Protein Atlas|eSLDB|GO|eSLDB|GO|GO|GO|eSLDB|GO|The Human Protein Atlas|GO|GO|eSLDB|GO|GO|eSLDB|GO|GO|GO|GO|GO|GO|GO|GO|GO|eSLDB|GO|MatrixDB|GO|MatrixDB|eSLDB|GO|GO|GO|LOCATE|Organelle|GO|GO|eSLDB|GO|GO|GO|GO|GO	BioGRID	9606
Q92569	Phosphatidylinositol 3-kinase regulatory subunit gamma	UniProtKB/Swiss-Prot/P	Cytosol(0.999)|Nucleus(0.94)	GO:0005737|GO:0005737|GO:0005737|GO:0005829|GO:0005942|GO:0043231|GO:0005634|GO:0005654	Predicted: SVM decision tree|Predicted: pTarget method|Predicted: PAML algorithm|Unknown: traceable author statement|Predicted: inferred from biological aspect of ancestor|Experimental: annotated protein expression (APE)|Predicted: SVM decision tree|Experimental: annotated protein expression (APE)	eSLDB|LOCATE|PA-GOSUB|GO|GO|The Human Protein Atlas|eSLDB|The Human Protein Atlas	IntAct|BioGRID	9606
Q9NWZ3	Interleukin-1 receptor-associated kinase 4	UniProtKB/Swiss-Prot/P	Cytosol(0.997)|Mitochondrion(0.7)|Nucleus(0.94)|Secretory-pathway(0.3)|Extracellular(0.3)|Membrane(0.86)	GO:0005737|GO:0005737|GO:0005829|GO:0005829|GO:0005739|GO:0005634|GO:0005730|GO:0010008|GO:0015630|GO:0005615|GO:0016020|GO:0005886	Predicted: inferred from biological aspect of ancestor|Predicted: PAML algorithm|Unknown: traceable author statement|Experimental: annotated protein expression (APE)|Predicted: SVM decision tree|Predicted: inferred from biological aspect of ancestor|Experimental: annotated protein expression (APE)|Unknown: traceable author statement|Experimental: annotated protein expression (APE)|Unknown: inferred from electronic annotation|Experimental: experimental|Unknown: traceable author statement	GO|PA-GOSUB|GO|The Human Protein Atlas|eSLDB|GO|The Human Protein Atlas|GO|The Human Protein Atlas|GO|MatrixDB|GO	BioGRID|HPRD	9606
O43187	Interleukin-1 receptor-associated kinase-like 2	UniProtKB/Swiss-Prot/P	Cytosol(0.987)|Nucleus(0.91)|Secretory-pathway(0.3)|Membrane(0.3)	GO:0005737|GO:0005737|GO:0005829|GO:0043231|GO:0005634|GO:0005634|GO:0010008|GO:0005886	Predicted: inferred from biological aspect of ancestor|Predicted: PAML algorithm|Unknown: traceable author statement|Experimental: annotated protein expression (APE)|Predicted: SVM decision tree|Predicted: inferred from biological aspect of ancestor|Unknown: traceable author statement|Unknown: traceable author statement	GO|PA-GOSUB|GO|The Human Protein Atlas|eSLDB|GO|GO|GO	HPRD|BioGRID	9606
O43353	Receptor-interacting serine/threonine-protein kinase 2	UniProtKB/Swiss-Prot/P	Cytosol(1)|Nucleus(0.8)	GO:0005737|GO:0005737|GO:0005737|GO:0005737|GO:0005829|GO:0005829|GO:0032991|GO:0005856|GO:0031982	Experimental: experimental|Experimental: inferred from direct assay|Predicted: pTarget method|Predicted: PAML algorithm|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: inferred from mutant phenotype|Experimental: inferred from direct assay|Experimental: inferred from direct assay	eSLDB|GO|LOCATE|PA-GOSUB|GO|The Human Protein Atlas|GO|GO|GO	BioGRID	9606
D3YTB5	Interleukin-1 receptor-associated kinase 1	UniProtKB/TrEmbl/P	Cytosol(0.8)|Nucleus(0.8)	GO:0005829|GO:0005634	Experimental: annotated protein expression (APE)|Experimental: annotated protein expression (APE)	The Human Protein Atlas|The Human Protein Atlas	BioGRID	9606
Q63ZY3	KN motif and ankyrin repeat domain-containing protein 2	UniProtKB/Swiss-Prot/P	Cytosol(0.982)|Mitochondrion(0.8)	GO:0005737|GO:0005737|GO:0005737|GO:0005739	Predicted: SVM decision tree|Experimental: inferred from direct assay|Predicted: PAML algorithm|Experimental: inferred from direct assay	eSLDB|GO|PA-GOSUB|GO	BioGRID	9606
Q8N381	Phosphoinositide-3-kinase, regulatory subunit 3	UniProtKB/TrEmbl/P	Cytosol(0.7)|Nucleus(0.7)	GO:0005737|GO:0005634	Predicted: pTarget method|Predicted: SVM decision tree	LOCATE|eSLDB	BioGRID	9606
Q7Z3W2	Uncharacterized protein DKFZp686F1293	UniProtKB/TrEmbl/P	Cytosol(0.7)|Nucleus(0.7)	GO:0005737|GO:0005634	Predicted: pTarget method|Predicted: SVM decision tree	LOCATE|eSLDB	BioGRID	9606
Q68CY7	Uncharacterized protein DKFZp686P05226	UniProtKB/TrEmbl/P	Cytosol(0.7)|Nucleus(0.7)	GO:0005737|GO:0005634	Predicted: pTarget method|Predicted: SVM decision tree	LOCATE|eSLDB	BioGRID	9606
G3V2F7	Ubiquitin-conjugating enzyme E2 variant 1	UniProtKB/TrEmbl/P	Nucleus(0.8)	GO:0005654	Experimental: annotated protein expression (APE)	The Human Protein Atlas	BioGRID	9606
E9PG40	Amyloid-beta A4 protein	UniProtKB/TrEmbl/P	Cytosol(0.8)|Secretory-pathway(0.8)	GO:0043231|GO:0005794	Experimental: annotated protein expression (APE)|Experimental: annotated protein expression (APE)	The Human Protein Atlas|The Human Protein Atlas	BioGRID	9606
P47985	Cytochrome b-c1 complex subunit Rieske, mitochondrial	UniProtKB/Swiss-Prot/P	Mitochondrion(1)|Extracellular(0.8)|Membrane(0.86)|Cytosol(0.8)	GO:0005739|GO:0005739|GO:0005739|GO:0005739|GO:0005739|GO:0005743|GO:0005750|GO:0005751|GO:0005576|GO:0045275|GO:0016021|GO:0019866	Predicted: SVM decision tree|Experimental: inferred from direct assay|Experimental: experimental|Predicted: PAML algorithm|Experimental: annotated protein expression (APE)|Unknown: traceable author statement|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: experimental|Experimental: experimental|Unknown: inferred from electronic annotation|Experimental: experimental	eSLDB|GO|Organelle|PA-GOSUB|The Human Protein Atlas|GO|GO|GO|MatrixDB|Organelle|GO|Organelle	BioGRID	9606
A0A0A0MRG2	Amyloid-beta A4 protein	UniProtKB/TrEmbl/P	Cytosol(0.8)|Secretory-pathway(0.8)|Membrane(0.7)	GO:0043231|GO:0005794|GO:0016021	Experimental: annotated protein expression (APE)|Experimental: annotated protein expression (APE)|Predicted: SVM decision tree	The Human Protein Atlas|The Human Protein Atlas|eSLDB	BioGRID	9606
Q68D39	Uncharacterized protein DKFZp686J04131	UniProtKB/TrEmbl/P	Secretory-pathway(0.7)|Cytosol(0.7)	GO:secretory_pathway|GO:0005737	Predicted: SVM decision tree|Predicted: PAML algorithm	eSLDB|PA-GOSUB	BioGRID	9606
Q69FE3	Interleukin-1 receptor-associated kinase 4 variant	UniProtKB/TrEmbl/P	Mitochondrion(0.7)	GO:0005739	Predicted: SVM decision tree	eSLDB	BioGRID	9606