Interactor	Canonical Name	Naming Convention	Major Loc With Loc Score	Minor Loc	Loc Experimental System Type	Loc Source DB	Interaction Source DB	Taxonomy ID
Q99466	Neurogenic locus notch homolog protein 4	UniProtKB/Swiss-Prot/P	Membrane(0.999)|Cytosol(0.3)|Nucleus(0.902)|Secretory-pathway(0.51)|Extracellular(0.86)	GO:0009986|GO:0005829|GO:0005634|GO:0005634|GO:0005654|GO:0005789|GO:0000139|GO:0005576|GO:0005576|GO:0016020|GO:0016021|GO:0005886|GO:0005886|GO:0005887	Experimental: inferred from direct assay|Unknown: traceable author statement|Unknown: traceable author statement|Experimental: experimental|Unknown: traceable author statement|Unknown: traceable author statement|Unknown: traceable author statement|Unknown: traceable author statement|Experimental: experimental|Experimental: experimental|Predicted: SVM decision tree|Unknown: traceable author statement|Experimental: experimental|Unknown: traceable author statement	GO|GO|GO|Organelle|GO|GO|GO|GO|MatrixDB|MatrixDB|eSLDB|GO|Organelle|GO		9606
P49768	Presenilin-1	UniProtKB/Swiss-Prot/P	Membrane(1)|Cytosol(1)|Mitochondrion(0.988)|Nucleus(1)|Secretory-pathway(1)|Extracellular(0.8)	GO:0009986|GO:0012505|GO:0043025|GO:0016235|GO:0048471|GO:0005938|GO:0005739|GO:0005739|GO:0005743|GO:0005634|GO:0005634|GO:0005634|GO:0031965|GO:0005640|GO:0005639|GO:0032991|GO:0005783|GO:0005783|GO:0005783|GO:0005791|GO:0005790|GO:0005789|GO:0005794|GO:0005794|GO:0005794|GO:0005794|GO:0000139|GO:0005765|GO:0030018|GO:0005813|GO:0005694|GO:0000776|GO:0030426|GO:0043198|GO:0030424|GO:0035253|GO:0005576|GO:0016020|GO:0016021|GO:0016021|GO:0045121|GO:0005886|GO:0005886|GO:0070765|GO:0005887|GO:0019866|GO:0031982|GO:0030054|GO:0030054|GO:0031594	Predicted: inferred from biological aspect of ancestor|Experimental: experimental|Predicted: inferred from biological aspect of ancestor|Experimental: inferred from direct assay|Predicted: inferred from biological aspect of ancestor|Predicted: inferred from biological aspect of ancestor|Experimental: inferred from direct assay|Experimental: experimental|Predicted: inferred from biological aspect of ancestor|Experimental: inferred from direct assay|Experimental: experimental|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: experimental|Experimental: inferred from mutant phenotype|Experimental: experimental|Experimental: inferred from direct assay|Experimental: experimental|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Unknown: inferred from electronic annotation|Experimental: experimental|Experimental: inferred from direct assay|Predicted: PAML algorithm|Experimental: annotated protein expression (APE)|Unknown: inferred from electronic annotation|Predicted: inferred from biological aspect of ancestor|Predicted: inferred from biological aspect of ancestor|Experimental: inferred from direct assay|Experimental: experimental|Experimental: inferred from direct assay|Predicted: inferred from biological aspect of ancestor|Predicted: inferred from biological aspect of ancestor|Predicted: inferred from biological aspect of ancestor|Predicted: inferred from biological aspect of ancestor|Experimental: experimental|Experimental: inferred from direct assay|Experimental: experimental|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: experimental|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: experimental|Experimental: experimental|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Predicted: inferred from biological aspect of ancestor	GO|Organelle|GO|GO|GO|GO|GO|Organelle|GO|GO|Organelle|The Human Protein Atlas|GO|GO|Organelle|GO|eSLDB|GO|Organelle|GO|GO|GO|eSLDB|GO|PA-GOSUB|The Human Protein Atlas|GO|GO|GO|GO|Organelle|GO|GO|GO|GO|GO|MatrixDB|GO|eSLDB|GO|GO|GO|Organelle|GO|GO|Organelle|eSLDB|GO|The Human Protein Atlas|GO	HPRD	9606
P49810	Presenilin-2	UniProtKB/Swiss-Prot/P	Membrane(1)|Cytosol(1)|Mitochondrion(0.7)|Nucleus(1)|Secretory-pathway(1)|Extracellular(0.8)	GO:0009986|GO:0012505|GO:0043025|GO:0048471|GO:0005938|GO:0005743|GO:0005634|GO:0005634|GO:0005637|GO:0005639|GO:0032991|GO:0005783|GO:0005783|GO:0005783|GO:0005789|GO:0005794|GO:0005794|GO:0005794|GO:0000139|GO:0005765|GO:0030018|GO:0005813|GO:0005694|GO:0000776|GO:0030426|GO:0043198|GO:0030424|GO:0035253|GO:0005576|GO:0016020|GO:0016021|GO:0045121|GO:0005886|GO:0005886|GO:0005887|GO:0019866|GO:0031594	Predicted: inferred from biological aspect of ancestor|Experimental: experimental|Predicted: inferred from biological aspect of ancestor|Predicted: inferred from biological aspect of ancestor|Predicted: inferred from biological aspect of ancestor|Predicted: inferred from biological aspect of ancestor|Experimental: experimental|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Experimental: experimental|Experimental: inferred from direct assay|Experimental: experimental|Experimental: inferred from direct assay|Experimental: experimental|Unknown: inferred from electronic annotation|Experimental: experimental|Experimental: inferred from direct assay|Predicted: PAML algorithm|Unknown: inferred from electronic annotation|Predicted: inferred from biological aspect of ancestor|Predicted: inferred from biological aspect of ancestor|Experimental: inferred from direct assay|Experimental: experimental|Experimental: inferred from direct assay|Predicted: inferred from biological aspect of ancestor|Predicted: inferred from biological aspect of ancestor|Predicted: inferred from biological aspect of ancestor|Predicted: inferred from biological aspect of ancestor|Experimental: experimental|Unknown: HDA|Experimental: experimental|Predicted: inferred from biological aspect of ancestor|Unknown: traceable author statement|Experimental: experimental|Experimental: inferred from direct assay|Experimental: experimental|Predicted: inferred from biological aspect of ancestor	GO|Organelle|GO|GO|GO|GO|Organelle|The Human Protein Atlas|GO|Organelle|GO|eSLDB|GO|Organelle|GO|eSLDB|GO|PA-GOSUB|GO|GO|GO|GO|Organelle|GO|GO|GO|GO|GO|MatrixDB|GO|eSLDB|GO|GO|Organelle|GO|Organelle|GO	HPRD	9606
P84022	Mothers against decapentaplegic homolog 3	UniProtKB/Swiss-Prot/P	Cytosol(1)|Nucleus(1)|Membrane(0.86)	GO:0005737|GO:0005737|GO:0005829|GO:0005829|GO:0071141|GO:0005634|GO:0005634|GO:0005634|GO:0005637|GO:0005654|GO:0005654|GO:0005667|GO:0000790|GO:0005886|GO:0043235	Experimental: experimental|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Experimental: experimental|Experimental: inferred from direct assay|Predicted: PAML algorithm|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Unknown: inferred from electronic annotation|Experimental: inferred from mutant phenotype	eSLDB|GO|GO|The Human Protein Atlas|GO|eSLDB|GO|PA-GOSUB|GO|GO|The Human Protein Atlas|GO|GO|GO|GO	BioGRID|HPRD	9606
Q9UHF1	Epidermal growth factor-like protein 7	UniProtKB/Swiss-Prot/P	Secretory-pathway(0.8)|Extracellular(0.991)|Membrane(0.8)	GO:secretory_pathway|GO:0005576|GO:0005576|GO:0005615|GO:0031012|GO:0031012|GO:0016020	Experimental: experimental|Predicted: inferred from sequence or structural similarity|Predicted: PAML algorithm|Unknown: inferred from electronic annotation|Unknown: HDA|Experimental: experimental|Experimental: experimental	eSLDB|GO|PA-GOSUB|GO|GO|MatrixDB|MatrixDB	BioGRID	9606
Q15369	Elongin-C	UniProtKB/Swiss-Prot/P	Cytosol(0.3)|Nucleus(0.996)|Membrane(0.8)	GO:0005829|GO:0005634|GO:0005634|GO:0005634|GO:0005654|GO:0070449|GO:0030054	Unknown: traceable author statement|Experimental: experimental|Predicted: pTarget method|Predicted: PAML algorithm|Unknown: traceable author statement|Predicted: inferred from biological aspect of ancestor|Experimental: annotated protein expression (APE)	GO|eSLDB|LOCATE|PA-GOSUB|GO|GO|The Human Protein Atlas	BioGRID	9606
Q9NR61	Delta-like protein 4	UniProtKB/Swiss-Prot/P	Extracellular(0.94)|Membrane(0.902)	GO:0005576|GO:0005576|GO:0016021|GO:0016021|GO:0005886	Experimental: experimental|Predicted: PAML algorithm|Experimental: experimental|Unknown: inferred from electronic annotation|Unknown: traceable author statement	MatrixDB|PA-GOSUB|eSLDB|GO|GO	HPRD	9606
Q00987	E3 ubiquitin-protein ligase Mdm2	UniProtKB/Swiss-Prot/P	Cytosol(0.972)|Nucleus(1)|Secretory-pathway(0.3)|Membrane(0.51)	GO:0005737|GO:0005737|GO:0005829|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0005730|GO:0005654|GO:0016604|GO:0032991|GO:0030666|GO:0005886|GO:0045202	Experimental: experimental|Experimental: inferred from mutant phenotype|Unknown: traceable author statement|Experimental: experimental|Experimental: inferred from direct assay|Predicted: pTarget method|Experimental: experimental|Predicted: PAML algorithm|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: inferred from mutant phenotype|Unknown: traceable author statement|Unknown: traceable author statement|Unknown: inferred from electronic annotation	eSLDB|GO|GO|eSLDB|GO|LOCATE|Organelle|PA-GOSUB|The Human Protein Atlas|GO|GO|GO|GO|GO|GO|GO	BioGRID	9606
B7Z5N5	Mothers against decapentaplegic homolog	UniProtKB/TrEmbl/P	Cytosol(0.8)|Nucleus(0.96)|Extracellular(0.8)	GO:0005829|GO:0005634|GO:0005730|GO:0005576	Experimental: annotated protein expression (APE)|Experimental: annotated protein expression (APE)|Experimental: annotated protein expression (APE)|Experimental: experimental	The Human Protein Atlas|The Human Protein Atlas|The Human Protein Atlas|MatrixDB	BioGRID	9606
Q969H0	F-box/WD repeat-containing protein 7	UniProtKB/Swiss-Prot/P	Secretory-pathway(0.7)|Cytosol(0.994)|Nucleus(0.991)	GO:secretory_pathway|GO:0019005|GO:0005737|GO:0005829|GO:0043231|GO:0005634|GO:0005634|GO:0005730|GO:0005654|GO:0005654	Predicted: SVM decision tree|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Unknown: traceable author statement|Experimental: annotated protein expression (APE)|Predicted: SVM decision tree|Predicted: PAML algorithm|Unknown: inferred from electronic annotation|Unknown: traceable author statement|Experimental: annotated protein expression (APE)	eSLDB|GO|GO|GO|The Human Protein Atlas|eSLDB|PA-GOSUB|GO|GO|The Human Protein Atlas	HPRD	9606
P04637	Cellular tumor antigen p53	UniProtKB/Swiss-Prot/P	Cytosol(0.998)|Mitochondrion(0.972)|Nucleus(1)|Secretory-pathway(0.3)	GO:0005622|GO:0005737|GO:0005737|GO:0005829|GO:0005739|GO:0005739|GO:0005759|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0005730|GO:0016363|GO:0005654|GO:0005654|GO:0016604|GO:0016605|GO:0005669|GO:0032991|GO:0005783|GO:0000790|GO:0005657	Experimental: inferred from direct assay|Experimental: experimental|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: experimental|Unknown: inferred from electronic annotation|Predicted: SVM decision tree|Experimental: inferred from direct assay|Predicted: pTarget method|Experimental: experimental|Predicted: PAML algorithm|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: inferred from mutant phenotype|Unknown: inferred from electronic annotation|Experimental: inferred from direct assay|Predicted: inferred from biological aspect of ancestor	GO|eSLDB|GO|GO|GO|Organelle|GO|eSLDB|GO|LOCATE|Organelle|PA-GOSUB|GO|GO|GO|The Human Protein Atlas|GO|GO|GO|GO|GO|GO|GO	BioGRID	9606
Q13485	Mothers against decapentaplegic homolog 4	UniProtKB/Swiss-Prot/P	Cytosol(1)|Nucleus(1)	GO:0005737|GO:0005737|GO:0005829|GO:0005829|GO:0071141|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0005654|GO:0005654|GO:0005667|GO:0032444|GO:0005813|GO:0005813|GO:0000790	Experimental: experimental|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: inferred from mutant phenotype|Experimental: experimental|Experimental: inferred from direct assay|Experimental: experimental|Predicted: PAML algorithm|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Predicted: inferred from physical interaction|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay	eSLDB|GO|GO|The Human Protein Atlas|GO|eSLDB|GO|Organelle|PA-GOSUB|GO|The Human Protein Atlas|GO|GO|GO|The Human Protein Atlas|GO	HPRD|BioGRID	9606
Q15796	Mothers against decapentaplegic homolog 2	UniProtKB/Swiss-Prot/P	Cytosol(0.998)|Nucleus(1)	GO:0005737|GO:0005737|GO:0005829|GO:0005829|GO:0071141|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0005730|GO:0005654|GO:0005667|GO:0032444|GO:0032991|GO:0000790	Predicted: SVM decision tree|Experimental: inferred from direct assay|Unknown: traceable author statement|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Experimental: experimental|Experimental: inferred from direct assay|Experimental: experimental|Predicted: PAML algorithm|Experimental: annotated protein expression (APE)|Experimental: annotated protein expression (APE)|Unknown: traceable author statement|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: inferred from mutant phenotype|Experimental: inferred from direct assay	eSLDB|GO|GO|The Human Protein Atlas|GO|eSLDB|GO|Organelle|PA-GOSUB|The Human Protein Atlas|The Human Protein Atlas|GO|GO|GO|GO|GO	HPRD|BioGRID	9606
Q06330	Recombining binding protein suppressor of hairless	UniProtKB/Swiss-Prot/P	Nucleus(1)|Cytosol(0.8)	GO:0002193|GO:0005737|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0005730|GO:0005654|GO:0005654|GO:0017053|GO:0005667	Experimental: inferred from direct assay|Experimental: inferred from direct assay|Predicted: SVM decision tree|Experimental: inferred from direct assay|Predicted: pTarget method|Experimental: experimental|Predicted: PAML algorithm|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Unknown: inferred from electronic annotation	GO|GO|eSLDB|GO|LOCATE|Organelle|PA-GOSUB|GO|GO|The Human Protein Atlas|GO|GO	HPRD	9606
Q92585	Mastermind-like protein 1	UniProtKB/Swiss-Prot/P	Nucleus(1)|Cytosol(0.8)	GO:0002193|GO:0043231|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0005654|GO:0005654|GO:0016607	Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: experimental|Experimental: inferred from direct assay|Experimental: experimental|Predicted: PAML algorithm|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Unknown: inferred from electronic annotation	GO|GO|eSLDB|GO|Human Proteinpedia|PA-GOSUB|GO|The Human Protein Atlas|GO	HPRD|BioGRID	9606
Q8IZL2	Mastermind-like protein 2	UniProtKB/Swiss-Prot/P	Cytosol(0.8)|Nucleus(1)	GO:0005829|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0005654|GO:0005654|GO:0016604|GO:0016607	Experimental: annotated protein expression (APE)|Predicted: SVM decision tree|Experimental: inferred from direct assay|Experimental: experimental|Predicted: pTarget method|Predicted: PAML algorithm|Unknown: traceable author statement|Experimental: annotated protein expression (APE)|Experimental: annotated protein expression (APE)|Unknown: inferred from electronic annotation	The Human Protein Atlas|eSLDB|GO|Human Proteinpedia|LOCATE|PA-GOSUB|GO|The Human Protein Atlas|The Human Protein Atlas|GO	HPRD	9606
Q96JK9	Mastermind-like protein 3	UniProtKB/Swiss-Prot/P	Nucleus(0.998)	GO:0005634|GO:0005634|GO:0005654|GO:0016607|GO:0016607	Predicted: SVM decision tree|Experimental: inferred from direct assay|Unknown: traceable author statement|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)	eSLDB|GO|GO|GO|The Human Protein Atlas	HPRD	9606
Q53GA5	Cellular tumor antigen p53	UniProtKB/TrEmbl/P	Cytosol(0.8)|Nucleus(0.94)	GO:0005737|GO:0005634|GO:0005634	Experimental: experimental|Experimental: experimental|Predicted: pTarget method	eSLDB|eSLDB|LOCATE	BioGRID	9606
G3XA89	E3 ubiquitin-protein ligase Mdm2	UniProtKB/TrEmbl/P	Cytosol(0.7)|Nucleus(0.94)	GO:0005737|GO:0005634|GO:0005634	Predicted: SVM decision tree|Predicted: pTarget method|Experimental: annotated protein expression (APE)	eSLDB|LOCATE|The Human Protein Atlas	BioGRID	9606
Q53XR6	Mothers against decapentaplegic homolog	UniProtKB/TrEmbl/P	Cytosol(0.8)|Nucleus(0.8)	GO:0005737|GO:0005634	Experimental: experimental|Experimental: experimental	eSLDB|eSLDB	BioGRID	9606
A7UKX8	E3 ubiquitin-protein ligase Mdm2	UniProtKB/TrEmbl/P	Nucleus(0.8)	GO:0005634	Experimental: annotated protein expression (APE)	The Human Protein Atlas	BioGRID	9606
A0A087X1Q1	Cellular tumor antigen p53	UniProtKB/TrEmbl/P	Nucleus(0.8)	GO:0005654	Experimental: annotated protein expression (APE)	The Human Protein Atlas	BioGRID	9606
A0A087WXZ1	Cellular tumor antigen p53	UniProtKB/TrEmbl/P	Nucleus(0.8)	GO:0005654	Experimental: annotated protein expression (APE)	The Human Protein Atlas	BioGRID	9606
A0A087WT22	Cellular tumor antigen p53	UniProtKB/TrEmbl/P	Nucleus(0.8)	GO:0005654	Experimental: annotated protein expression (APE)	The Human Protein Atlas	BioGRID	9606
Q96DS0	MDM2 variant FB55	UniProtKB/TrEmbl/P	Nucleus(0.7)	GO:0005634	Predicted: PAML algorithm	PA-GOSUB	BioGRID	9606
