Interactor	Canonical Name	Naming Convention	Major Loc With Loc Score	Minor Loc	Loc Experimental System Type	Loc Source DB	Interaction Source DB	Taxonomy ID
Q9ULT6	E3 ubiquitin-protein ligase ZNRF3	UniProtKB/Swiss-Prot/P	Secretory-pathway(0.86)|Extracellular(0.8)|Membrane(0.958)	GO:0005783|GO:0005794|GO:0005576|GO:0016021|GO:0005886|GO:0005887	Experimental: experimental|Unknown: unspecified method|Experimental: experimental|Predicted: SVM decision tree|Unknown: traceable author statement|Experimental: inferred from direct assay	Human Proteinpedia|The Human Protein Atlas|MatrixDB|eSLDB|GO|GO		9606
O75581	Low-density lipoprotein receptor-related protein 6	UniProtKB/Swiss-Prot/P	Secretory-pathway(0.999)|Membrane(1)|Cytosol(0.7)|Extracellular(0.958)	GO:secretory_pathway|GO:0009986|GO:0043025|GO:0005783|GO:0005794|GO:0005769|GO:0031901|GO:0031410|GO:0005576|GO:0005576|GO:0005576|GO:0016020|GO:0016021|GO:0005886|GO:0005886|GO:0005901|GO:0043235|GO:0045202	Predicted: SVM decision tree|Experimental: inferred from direct assay|Predicted: inferred from biological aspect of ancestor|Unknown: inferred from electronic annotation|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Unknown: traceable author statement|Experimental: inferred from direct assay|Unknown: traceable author statement|Experimental: experimental|Predicted: PAML algorithm|Experimental: experimental|Unknown: inferred from electronic annotation|Experimental: inferred from direct assay|Experimental: experimental|Experimental: inferred from direct assay|Predicted: inferred from biological aspect of ancestor|Predicted: inferred from biological aspect of ancestor	eSLDB|GO|GO|GO|GO|GO|GO|GO|GO|MatrixDB|PA-GOSUB|MatrixDB|GO|GO|Organelle|GO|GO|GO	IntAct|DIP|BioGRID	9606
O75084	Frizzled-7	UniProtKB/Swiss-Prot/P	Nucleus(0.8)|Secretory-pathway(0.8)|Extracellular(0.8)|Membrane(1)	GO:0005654|GO:0055038|GO:0005576|GO:0016021|GO:0016021|GO:0005886|GO:0005886|GO:0005886|GO:0005886|GO:0005886	Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Experimental: experimental|Experimental: experimental|Unknown: traceable author statement|Experimental: inferred from direct assay|Experimental: experimental|Predicted: pTarget method|Experimental: experimental|Predicted: PAML algorithm	The Human Protein Atlas|GO|MatrixDB|eSLDB|GO|GO|Human Proteinpedia|LOCATE|Organelle|PA-GOSUB	BioGRID	9606
O75473	Leucine-rich repeat-containing G-protein coupled receptor 5	UniProtKB/Swiss-Prot/P	Secretory-pathway(0.8)|Extracellular(0.8)|Membrane(0.998)	GO:0032588|GO:0005576|GO:0016021|GO:0005886|GO:0005886|GO:0005886|GO:0005887	Experimental: inferred from direct assay|Experimental: experimental|Experimental: experimental|Unknown: traceable author statement|Experimental: experimental|Predicted: PAML algorithm|Experimental: inferred from direct assay	GO|MatrixDB|eSLDB|GO|Organelle|PA-GOSUB|GO	BioGRID	9606
Q9ULV1	Frizzled-4	UniProtKB/Swiss-Prot/P	Membrane(1)|Cytosol(0.8)|Nucleus(0.8)|Secretory-pathway(0.51)|Extracellular(0.8)	GO:0009986|GO:0005829|GO:0005654|GO:0030665|GO:0030669|GO:0030425|GO:0005576|GO:0016021|GO:0016021|GO:0005886|GO:0005886|GO:0005886|GO:0005886|GO:0005887|GO:0005911	Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: annotated protein expression (APE)|Unknown: traceable author statement|Unknown: traceable author statement|Predicted: inferred from sequence or structural similarity|Experimental: experimental|Experimental: experimental|Predicted: inferred from biological aspect of ancestor|Experimental: inferred from direct assay|Predicted: pTarget method|Predicted: PAML algorithm|Experimental: annotated protein expression (APE)|Unknown: inferred by curator|Unknown: inferred from electronic annotation	GO|The Human Protein Atlas|The Human Protein Atlas|GO|GO|GO|MatrixDB|eSLDB|GO|GO|LOCATE|PA-GOSUB|The Human Protein Atlas|GO|GO	BioGRID	9606
O60353	Frizzled-6	UniProtKB/Swiss-Prot/P	Membrane(1)|Secretory-pathway(0.3)|Extracellular(0.8)	GO:0009986|GO:0030659|GO:0005576|GO:0016021|GO:0016021|GO:0005886|GO:0005886|GO:0005886|GO:0005886|GO:0005886|GO:0016327|GO:0005887|GO:0016324	Unknown: inferred from electronic annotation|Unknown: inferred from electronic annotation|Experimental: experimental|Predicted: SVM decision tree|Predicted: inferred from biological aspect of ancestor|Experimental: inferred from direct assay|Predicted: pTarget method|Experimental: experimental|Predicted: PAML algorithm|Experimental: annotated protein expression (APE)|Unknown: inferred from electronic annotation|Predicted: inferred from sequence or structural similarity|Unknown: inferred from electronic annotation	GO|GO|MatrixDB|eSLDB|GO|GO|LOCATE|Organelle|PA-GOSUB|The Human Protein Atlas|GO|GO|GO	IntAct|DIP	9606
Q9BXY4	R-spondin-3	UniProtKB/Swiss-Prot/P	Secretory-pathway(0.91)|Extracellular(0.958)|Membrane(0.8)	GO:secretory_pathway|GO:0005794|GO:0005576|GO:0005576|GO:0031012|GO:0016020	Predicted: SVM decision tree|Predicted: PAML algorithm|Unknown: non-traceable author statement|Predicted: PAML algorithm|Experimental: experimental|Experimental: experimental	eSLDB|PA-GOSUB|GO|PA-GOSUB|MatrixDB|MatrixDB	BioGRID	9606
Q6UXX9	R-spondin-2	UniProtKB/Swiss-Prot/P	Secretory-pathway(0.7)|Membrane(0.86)|Extracellular(0.987)	GO:secretory_pathway|GO:0009986|GO:0005576|GO:0005576|GO:0005576|GO:0031012|GO:0016020	Predicted: SVM decision tree|Unknown: inferred from electronic annotation|Unknown: non-traceable author statement|Predicted: pTarget method|Predicted: PAML algorithm|Experimental: experimental|Experimental: experimental	eSLDB|GO|GO|LOCATE|PA-GOSUB|MatrixDB|MatrixDB	BioGRID	9606
P04792	Heat shock protein beta-1	UniProtKB/Swiss-Prot/P	Cytosol(1)|Nucleus(0.96)|Extracellular(0.86)|Membrane(0.98)	GO:0005737|GO:0005737|GO:0005737|GO:0005737|GO:0005829|GO:0005829|GO:0000502|GO:0005634|GO:0005634|GO:0030018|GO:0005856|GO:0005856|GO:0005819|GO:0005615|GO:0031012|GO:0016020|GO:0005886|GO:0005886|GO:0070062|GO:0005925	Experimental: experimental|Unknown: traceable author statement|Experimental: experimental|Predicted: PAML algorithm|Unknown: traceable author statement|Experimental: annotated protein expression (APE)|Predicted: inferred from sequence or structural similarity|Experimental: experimental|Experimental: inferred from direct assay|Unknown: inferred from electronic annotation|Unknown: traceable author statement|Experimental: experimental|Unknown: inferred from electronic annotation|Unknown: HDA|Experimental: experimental|Experimental: experimental|Unknown: inferred from electronic annotation|Experimental: annotated protein expression (APE)|Unknown: HDA|Unknown: HDA	eSLDB|GO|Human Proteinpedia|PA-GOSUB|GO|The Human Protein Atlas|GO|eSLDB|GO|GO|GO|Organelle|GO|GO|MatrixDB|MatrixDB|GO|The Human Protein Atlas|GO|GO	BioGRID|IntAct	9606
Q9BXB1	Leucine-rich repeat-containing G-protein coupled receptor 4	UniProtKB/Swiss-Prot/P	Cytosol(0.8)|Extracellular(0.8)|Membrane(0.987)	GO:0005815|GO:0005576|GO:0016021|GO:0005886|GO:0005886|GO:0005887	Experimental: annotated protein expression (APE)|Experimental: experimental|Predicted: SVM decision tree|Unknown: traceable author statement|Predicted: PAML algorithm|Experimental: inferred from direct assay	The Human Protein Atlas|MatrixDB|eSLDB|GO|PA-GOSUB|GO	IntAct|DIP|BioGRID	9606
Q2MKA7	R-spondin-1	UniProtKB/Swiss-Prot/P	Nucleus(0.79)|Secretory-pathway(0.7)|Extracellular(0.958)|Membrane(0.8)	GO:0005634|GO:0005634|GO:0005794|GO:0005576|GO:0005576|GO:0031012|GO:0016020	Predicted: SVM decision tree|Unknown: inferred from electronic annotation|Predicted: PAML algorithm|Unknown: non-traceable author statement|Predicted: PAML algorithm|Experimental: experimental|Experimental: experimental	eSLDB|GO|PA-GOSUB|GO|PA-GOSUB|MatrixDB|MatrixDB	IntAct|DIP|BioGRID	9606
O14641	Segment polarity protein dishevelled homolog DVL-2	UniProtKB/Swiss-Prot/P	Cytosol(0.999)|Nucleus(1)|Secretory-pathway(0.86)|Extracellular(0.8)|Membrane(0.3)	GO:0045177|GO:0016235|GO:0005737|GO:0005737|GO:0005737|GO:0005829|GO:0005634|GO:0005654|GO:0005654|GO:0016604|GO:0016604|GO:0031410|GO:0045334|GO:0005576|GO:0016328	Unknown: inferred from electronic annotation|Experimental: inferred from direct assay|Experimental: experimental|Experimental: inferred from direct assay|Predicted: PAML algorithm|Predicted: inferred from biological aspect of ancestor|Predicted: inferred from sequence or structural similarity|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Unknown: traceable author statement|Experimental: experimental|Unknown: inferred from electronic annotation	GO|GO|eSLDB|GO|PA-GOSUB|GO|GO|GO|The Human Protein Atlas|GO|The Human Protein Atlas|GO|GO|MatrixDB|GO	BioGRID	9606
Q59ER8	Leucine-rich repeat-containing G protein-coupled receptor 4 variant	UniProtKB/TrEmbl/P	Membrane(0.7)	GO:0016021	Predicted: SVM decision tree	eSLDB	BioGRID	9606
Q5VTD9	Zinc finger protein Gfi-1b	UniProtKB/Swiss-Prot/P	Nucleus(0.999)	GO:0005634|GO:0005634|GO:0005634|GO:0016363|GO:0005667	Predicted: SVM decision tree|Experimental: inferred from direct assay|Predicted: PAML algorithm|Experimental: inferred from direct assay|Experimental: inferred from direct assay	eSLDB|GO|PA-GOSUB|GO|GO	BioGRID|IntAct|HPRD	9606
P61088	Ubiquitin-conjugating enzyme E2 N	UniProtKB/Swiss-Prot/P	Cytosol(1)|Nucleus(1)	GO:0000151|GO:0005737|GO:0005737|GO:0005737|GO:0005737|GO:0005829|GO:0031372|GO:0035370|GO:0005634|GO:0005634|GO:0001650|GO:0001650|GO:0005654|GO:0032991|GO:0070062	Experimental: inferred from direct assay|Predicted: SVM decision tree|Unknown: traceable author statement|Experimental: experimental|Predicted: PAML algorithm|Unknown: traceable author statement|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Unknown: traceable author statement|Experimental: inferred from direct assay|Unknown: HDA	GO|eSLDB|GO|Human Proteinpedia|PA-GOSUB|GO|GO|GO|GO|The Human Protein Atlas|GO|The Human Protein Atlas|GO|GO|GO	IntAct|BioGRID	9606