Interactor	Canonical Name	Naming Convention	Major Loc With Loc Score	Minor Loc	Loc Experimental System Type	Loc Source DB	Interaction Source DB	Taxonomy ID
Q9ULV1	Frizzled-4	UniProtKB/Swiss-Prot/P	Membrane(1)|Cytosol(0.8)|Nucleus(0.8)|Secretory-pathway(0.51)|Extracellular(0.8)	GO:0009986|GO:0005829|GO:0005654|GO:0030665|GO:0030669|GO:0030425|GO:0005576|GO:0016021|GO:0016021|GO:0005886|GO:0005886|GO:0005886|GO:0005886|GO:0005887|GO:0005911	Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: annotated protein expression (APE)|Unknown: traceable author statement|Unknown: traceable author statement|Predicted: inferred from sequence or structural similarity|Experimental: experimental|Experimental: experimental|Predicted: inferred from biological aspect of ancestor|Experimental: inferred from direct assay|Predicted: pTarget method|Predicted: PAML algorithm|Experimental: annotated protein expression (APE)|Unknown: inferred by curator|Unknown: inferred from electronic annotation	GO|The Human Protein Atlas|The Human Protein Atlas|GO|GO|GO|MatrixDB|eSLDB|GO|GO|LOCATE|PA-GOSUB|The Human Protein Atlas|GO|GO		9606
Q12959	Disks large homolog 1	UniProtKB/Swiss-Prot/P	Membrane(1)|Cytosol(1)|Nucleus(0.8)|Secretory-pathway(0.972)|Extracellular(0.96)	GO:0043219|GO:0035748|GO:0005737|GO:0005737|GO:0005737|GO:0005829|GO:0048471|GO:0043231|GO:0005634|GO:0005783|GO:0005789|GO:0005794|GO:0005874|GO:0031253|GO:0014069|GO:0033268|GO:0005576|GO:0031012|GO:0045121|GO:0005886|GO:0005886|GO:0005886|GO:0042383|GO:0001772|GO:0009898|GO:0016328|GO:0097025|GO:0008328|GO:0016324|GO:0016323|GO:0070062|GO:0030054|GO:0005911|GO:0014704|GO:0005923|GO:0031594|GO:0045211	Unknown: inferred from electronic annotation|Unknown: inferred from electronic annotation|Predicted: SVM decision tree|Experimental: inferred from direct assay|Predicted: PAML algorithm|Unknown: traceable author statement|Experimental: inferred from direct assay|Unknown: unspecified method|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Unknown: inferred from electronic annotation|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Unknown: inferred from electronic annotation|Predicted: inferred from biological aspect of ancestor|Unknown: inferred from electronic annotation|Experimental: experimental|Experimental: experimental|Unknown: inferred from electronic annotation|Unknown: traceable author statement|Experimental: experimental|Unknown: unspecified method|Unknown: inferred from electronic annotation|Unknown: traceable author statement|Experimental: inferred from direct assay|Unknown: inferred from electronic annotation|Experimental: inferred from direct assay|Predicted: inferred from biological aspect of ancestor|Unknown: inferred from electronic annotation|Experimental: inferred from direct assay|Unknown: HDA|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Unknown: traceable author statement|Experimental: inferred from direct assay|Unknown: inferred from electronic annotation|Predicted: inferred from biological aspect of ancestor	GO|GO|eSLDB|GO|PA-GOSUB|GO|GO|The Human Protein Atlas|GO|GO|GO|GO|GO|GO|GO|GO|MatrixDB|MatrixDB|GO|GO|Organelle|The Human Protein Atlas|GO|GO|GO|GO|GO|GO|GO|GO|GO|GO|GO|GO|GO|GO|GO	HPRD	9606
O14745	Na(+)/H(+) exchange regulatory cofactor NHE-RF1	UniProtKB/Swiss-Prot/P	Cytosol(1)|Nucleus(0.94)|Membrane(1)|Extracellular(0.8)	GO:0012505|GO:0005737|GO:0005737|GO:0005737|GO:0048471|GO:0043231|GO:0005634|GO:0005634|GO:0032426|GO:0005856|GO:0005815|GO:0015629|GO:0071944|GO:0001726|GO:0005902|GO:0031528|GO:0031526|GO:0030175|GO:0097225|GO:0005576|GO:0016020|GO:0045121|GO:0005886|GO:0016324|GO:0031982|GO:0070062	Unknown: inferred from electronic annotation|Experimental: inferred from direct assay|Experimental: experimental|Predicted: PAML algorithm|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Predicted: SVM decision tree|Experimental: inferred from direct assay|Unknown: inferred from electronic annotation|Experimental: experimental|Experimental: annotated protein expression (APE)|Unknown: traceable author statement|Experimental: inferred from direct assay|Unknown: inferred from electronic annotation|Experimental: inferred from direct assay|Predicted: inferred from sequence or structural similarity|Unknown: inferred from electronic annotation|Unknown: inferred from electronic annotation|Predicted: inferred from sequence or structural similarity|Experimental: experimental|Experimental: inferred from direct assay|Unknown: inferred from electronic annotation|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Unknown: HDA|Unknown: HDA	GO|GO|Human Proteinpedia|PA-GOSUB|GO|The Human Protein Atlas|eSLDB|GO|GO|Organelle|The Human Protein Atlas|GO|GO|GO|GO|GO|GO|GO|GO|MatrixDB|GO|GO|The Human Protein Atlas|GO|GO|GO	IntAct	9606
P78352	Disks large homolog 4	UniProtKB/Swiss-Prot/P	Cytosol(1)|Secretory-pathway(0.937)|Membrane(1)|Extracellular(0.8)	GO:0005737|GO:0005737|GO:0005737|GO:0005829|GO:0043231|GO:0005783|GO:0030666|GO:0008021|GO:0005856|GO:0030863|GO:0032839|GO:0043197|GO:0014069|GO:0044306|GO:0044309|GO:0044300|GO:0044224|GO:0005576|GO:0008076|GO:0005886|GO:0031234|GO:0008328|GO:0032281|GO:0016323|GO:0030054|GO:0045202|GO:0060076|GO:0045211	Predicted: SVM decision tree|Predicted: inferred from sequence or structural similarity|Predicted: PAML algorithm|Unknown: traceable author statement|Experimental: annotated protein expression (APE)|Predicted: inferred from sequence or structural similarity|Unknown: traceable author statement|Predicted: inferred from sequence or structural similarity|Experimental: experimental|Experimental: inferred from direct assay|Predicted: inferred from sequence or structural similarity|Predicted: inferred from sequence or structural similarity|Predicted: inferred from sequence or structural similarity|Predicted: inferred from sequence or structural similarity|Predicted: inferred from sequence or structural similarity|Unknown: inferred from electronic annotation|Predicted: inferred from sequence or structural similarity|Experimental: experimental|Predicted: inferred from sequence or structural similarity|Unknown: traceable author statement|Predicted: inferred from sequence or structural similarity|Predicted: inferred from sequence or structural similarity|Predicted: inferred from sequence or structural similarity|Predicted: inferred from biological aspect of ancestor|Predicted: inferred from sequence or structural similarity|Experimental: inferred from direct assay|Predicted: inferred from sequence or structural similarity|Experimental: inferred from direct assay	eSLDB|GO|PA-GOSUB|GO|The Human Protein Atlas|GO|GO|GO|Organelle|GO|GO|GO|GO|GO|GO|GO|GO|MatrixDB|GO|GO|GO|GO|GO|GO|GO|GO|GO|GO	BioGRID|HPRD	9606
Q15700	Disks large homolog 2	UniProtKB/Swiss-Prot/P	Cytosol(0.987)|Nucleus(0.7)|Membrane(1)|Extracellular(0.8)	GO:0005737|GO:0005737|GO:0005829|GO:0043231|GO:0005634|GO:0014069|GO:0044224|GO:0005576|GO:0016020|GO:0008076|GO:0005886|GO:0005886|GO:0005886|GO:0008328|GO:0016323|GO:0030054|GO:0045211	Predicted: SVM decision tree|Predicted: PAML algorithm|Unknown: traceable author statement|Experimental: annotated protein expression (APE)|Predicted: pTarget method|Predicted: inferred from sequence or structural similarity|Predicted: inferred from sequence or structural similarity|Experimental: experimental|Predicted: inferred from sequence or structural similarity|Predicted: inferred from sequence or structural similarity|Unknown: traceable author statement|Experimental: experimental|Experimental: annotated protein expression (APE)|Predicted: inferred from biological aspect of ancestor|Predicted: inferred from biological aspect of ancestor|Unknown: inferred from electronic annotation|Predicted: inferred from biological aspect of ancestor	eSLDB|PA-GOSUB|GO|The Human Protein Atlas|LOCATE|GO|GO|MatrixDB|GO|GO|GO|Organelle|The Human Protein Atlas|GO|GO|GO|GO	HPRD	9606
P20339	Ras-related protein Rab-5A	UniProtKB/Swiss-Prot/P	Cytosol(1)|Secretory-pathway(1)|Membrane(1)|Extracellular(0.8)	GO:0043025|GO:0005737|GO:0005737|GO:0005737|GO:0005829|GO:0005794|GO:0005768|GO:0005768|GO:0005769|GO:0031901|GO:0010008|GO:0030139|GO:0030670|GO:0042470|GO:0030665|GO:0008021|GO:0015629|GO:0001726|GO:0030425|GO:0043679|GO:0030424|GO:0005576|GO:0016020|GO:0045121|GO:0005886|GO:0005886|GO:0070062|GO:0043195	Predicted: inferred from sequence or structural similarity|Experimental: experimental|Experimental: inferred from direct assay|Predicted: PAML algorithm|Experimental: inferred from direct assay|Predicted: PAML algorithm|Experimental: experimental|Predicted: inferred from sequence or structural similarity|Experimental: inferred from direct assay|Unknown: traceable author statement|Experimental: inferred from direct assay|Predicted: inferred from biological aspect of ancestor|Unknown: inferred from electronic annotation|Unknown: inferred from electronic annotation|Unknown: traceable author statement|Predicted: inferred from sequence or structural similarity|Unknown: inferred from electronic annotation|Unknown: inferred from electronic annotation|Predicted: inferred from sequence or structural similarity|Predicted: inferred from sequence or structural similarity|Predicted: inferred from sequence or structural similarity|Experimental: experimental|Experimental: experimental|Unknown: inferred from electronic annotation|Predicted: inferred from biological aspect of ancestor|Predicted: PAML algorithm|Unknown: HDA|Experimental: inferred from direct assay	GO|eSLDB|GO|PA-GOSUB|GO|PA-GOSUB|eSLDB|GO|GO|GO|GO|GO|GO|GO|GO|GO|GO|GO|GO|GO|GO|MatrixDB|eSLDB|GO|GO|PA-GOSUB|GO|GO	BioGRID	9606
P32121	Beta-arrestin-2	UniProtKB/Swiss-Prot/P	Cytosol(0.999)|Nucleus(0.988)|Secretory-pathway(0.972)|Membrane(0.99)|Extracellular(0.8)	GO:0005905|GO:0005737|GO:0005737|GO:0005829|GO:0043231|GO:0043231|GO:0005634|GO:0005634|GO:0005634|GO:0005768|GO:0031410|GO:0030139|GO:0043197|GO:0014069|GO:0005576|GO:0005886|GO:0005886|GO:0016323|GO:0045211	Unknown: inferred from electronic annotation|Experimental: experimental|Experimental: inferred from direct assay|Unknown: traceable author statement|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: experimental|Experimental: inferred from direct assay|Predicted: PAML algorithm|Unknown: inferred from electronic annotation|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Unknown: inferred from electronic annotation|Unknown: inferred from electronic annotation|Experimental: experimental|Experimental: inferred from direct assay|Experimental: experimental|Unknown: inferred from electronic annotation|Unknown: inferred from electronic annotation	GO|eSLDB|GO|GO|GO|The Human Protein Atlas|eSLDB|GO|PA-GOSUB|GO|GO|GO|GO|GO|MatrixDB|GO|Organelle|GO|GO	HPRD	9606
Q00604	Norrin	UniProtKB/Swiss-Prot/P	Secretory-pathway(0.8)|Membrane(0.96)|Cytosol(0.8)|Nucleus(0.992)|Extracellular(0.988)	GO:secretory_pathway|GO:0009986|GO:0043231|GO:0005634|GO:0005634|GO:0005730|GO:0005576|GO:0005615|GO:0031012|GO:0016020	Experimental: experimental|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: experimental|Experimental: annotated protein expression (APE)|Experimental: annotated protein expression (APE)|Predicted: PAML algorithm|Experimental: inferred from direct assay|Experimental: experimental|Experimental: experimental	eSLDB|GO|The Human Protein Atlas|Human Proteinpedia|The Human Protein Atlas|The Human Protein Atlas|PA-GOSUB|GO|MatrixDB|MatrixDB	IntAct|BioGRID	9606
Q5TCQ9	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3	UniProtKB/Swiss-Prot/P	Cytosol(0.91)|Nucleus(0.79)|Extracellular(0.8)|Membrane(0.986)	GO:0005737|GO:0005737|GO:0005634|GO:0005634|GO:0005576|GO:0016020|GO:0005886|GO:0030054|GO:0030054|GO:0005923	Predicted: SVM decision tree|Predicted: pTarget method|Predicted: SVM decision tree|Unknown: inferred from electronic annotation|Experimental: experimental|Unknown: non-traceable author statement|Unknown: inferred from electronic annotation|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Unknown: inferred from electronic annotation	eSLDB|LOCATE|eSLDB|GO|MatrixDB|GO|GO|GO|The Human Protein Atlas|GO	HPRD	9606
P46379	Large proline-rich protein BAG6	UniProtKB/Swiss-Prot/P	Cytosol(1)|Nucleus(0.992)|Extracellular(0.8)|Membrane(0.958)	GO:0005737|GO:0005829|GO:0005829|GO:0071818|GO:0043231|GO:0005634|GO:0005654|GO:0005654|GO:0005576|GO:0016020|GO:0016020|GO:0016021|GO:0070062	Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: experimental|Unknown: HDA|Experimental: experimental|Predicted: SVM decision tree|Experimental: inferred from direct assay	GO|GO|The Human Protein Atlas|GO|GO|GO|GO|The Human Protein Atlas|MatrixDB|GO|MatrixDB|eSLDB|GO	BioGRID	9606
O95859	Tetraspanin-12	UniProtKB/Swiss-Prot/P	Cytosol(0.96)|Extracellular(0.8)|Membrane(0.971)	GO:0043231|GO:0015630|GO:0005576|GO:0016020|GO:0016021|GO:0016021|GO:0005887	Experimental: annotated protein expression (APE)|Experimental: annotated protein expression (APE)|Experimental: experimental|Unknown: traceable author statement|Experimental: experimental|Unknown: traceable author statement|Predicted: inferred from sequence or structural similarity	The Human Protein Atlas|The Human Protein Atlas|MatrixDB|GO|eSLDB|GO|GO	IntAct	9606
O14641	Segment polarity protein dishevelled homolog DVL-2	UniProtKB/Swiss-Prot/P	Cytosol(0.999)|Nucleus(1)|Secretory-pathway(0.86)|Extracellular(0.8)|Membrane(0.3)	GO:0045177|GO:0016235|GO:0005737|GO:0005737|GO:0005737|GO:0005829|GO:0005634|GO:0005654|GO:0005654|GO:0016604|GO:0016604|GO:0031410|GO:0045334|GO:0005576|GO:0016328	Unknown: inferred from electronic annotation|Experimental: inferred from direct assay|Experimental: experimental|Experimental: inferred from direct assay|Predicted: PAML algorithm|Predicted: inferred from biological aspect of ancestor|Predicted: inferred from sequence or structural similarity|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Unknown: traceable author statement|Experimental: experimental|Unknown: inferred from electronic annotation	GO|GO|eSLDB|GO|PA-GOSUB|GO|GO|GO|The Human Protein Atlas|GO|The Human Protein Atlas|GO|GO|MatrixDB|GO	HPRD	9606
Q9UPQ7	E3 ubiquitin-protein ligase PDZRN3	UniProtKB/Swiss-Prot/P	Cytosol(0.999)|Nucleus(0.999)|Membrane(0.79)	GO:0005737|GO:0005737|GO:0005737|GO:0005829|GO:0005829|GO:0005634|GO:0005634|GO:0005634|GO:0005634|GO:0005654|GO:0030054|GO:0031594	Experimental: experimental|Predicted: pTarget method|Predicted: PAML algorithm|Experimental: inferred from direct assay|Experimental: annotated protein expression (APE)|Predicted: SVM decision tree|Experimental: inferred from direct assay|Predicted: pTarget method|Experimental: annotated protein expression (APE)|Experimental: inferred from direct assay|Unknown: inferred from electronic annotation|Predicted: inferred from biological aspect of ancestor	Human Proteinpedia|LOCATE|PA-GOSUB|GO|The Human Protein Atlas|eSLDB|GO|LOCATE|The Human Protein Atlas|GO|GO|GO	BioGRID	9606
Q9ULT6	E3 ubiquitin-protein ligase ZNRF3	UniProtKB/Swiss-Prot/P	Secretory-pathway(0.86)|Extracellular(0.8)|Membrane(0.958)	GO:0005783|GO:0005794|GO:0005576|GO:0016021|GO:0005886|GO:0005887	Experimental: experimental|Unknown: unspecified method|Experimental: experimental|Predicted: SVM decision tree|Unknown: traceable author statement|Experimental: inferred from direct assay	Human Proteinpedia|The Human Protein Atlas|MatrixDB|eSLDB|GO|GO	BioGRID	9606
Q6UXH1	Cysteine-rich with EGF-like domain protein 2	UniProtKB/Swiss-Prot/P	Secretory-pathway(0.853)|Extracellular(0.958)|Membrane(0.8)	GO:secretory_pathway|GO:0005783|GO:0005794|GO:0005576|GO:0005615|GO:0031012|GO:0016020	Predicted: SVM decision tree|Unknown: inferred from electronic annotation|Unknown: inferred from electronic annotation|Predicted: PAML algorithm|Unknown: inferred from electronic annotation|Experimental: experimental|Experimental: experimental	eSLDB|GO|GO|PA-GOSUB|GO|MatrixDB|MatrixDB	IntAct	9606
B7ZAG0	E3 ubiquitin-protein ligase PDZRN3	UniProtKB/TrEmbl/P	Cytosol(0.8)|Nucleus(0.8)	GO:0005829|GO:0005634	Experimental: annotated protein expression (APE)|Experimental: annotated protein expression (APE)	The Human Protein Atlas|The Human Protein Atlas	BioGRID	9606
E7ENB6	E3 ubiquitin-protein ligase PDZRN3	UniProtKB/TrEmbl/P	Cytosol(0.8)|Nucleus(0.8)	GO:0005829|GO:0005634	Experimental: annotated protein expression (APE)|Experimental: annotated protein expression (APE)	The Human Protein Atlas|The Human Protein Atlas	BioGRID	9606