A0A1W2PPJ9

STE20-related kinase adapter protein alpha // UniProt Profile

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Species	H. sapiens
Number of Interactions	15 / 26
Average Interaction Score	0.802

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

A0A1W2PPJ9

Interaction Score

0.96

O14980

(UniProtKB/Swiss-Prot/P) Details

Exportin-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear envelope (GO:0005635)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Cajal body (GO:0015030)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Kinetochore (GO:0000776)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Extracellular	Host cell (GO:0043657)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed
Secretory-pathway	Annulate lamellae (GO:0005642)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A1W2PPJ9

Interaction Score

0.959

Q15831

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase STK11

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	TCR signalosome (GO:0036398)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A1W2PPJ9

Interaction Score

0.958

P34897

(UniProtKB/Swiss-Prot/P) Details

Serine hydroxymethyltransferase, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial nucleoid (GO:0042645)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial intermembrane space (GO:0005758)	1	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	BRISC complex (GO:0070552)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.998	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A1W2PPJ9

Interaction Score

0.958

P07900

(UniProtKB/Swiss-Prot/P) Details

Heat shock protein HSP 90-alpha

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.987	Unknown: traceable author statement	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.987	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosomal lumen (GO:0043202)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endocytic vesicle lumen (GO:0071682)	0.657	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Melanosome (GO:0042470)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.657	Unknown: traceable author statement	GO	PubMed
Membrane	Dendritic growth cone (GO:0044294)	0.996	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Ruffle membrane (GO:0032587)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axonal growth cone (GO:0044295)	0.996	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.996	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.996	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A1W2PPJ9

Interaction Score

0.947

Q9BQE6

(UniProtKB/Swiss-Prot/P) Details

LBH domain-containing protein 1

A0A1W2PPJ9

Interaction Score

0.945

Q6PCT2

(UniProtKB/Swiss-Prot/P) Details

F-box/LRR-repeat protein 19

A0A1W2PPJ9

Interaction Score

0.928

Q9Y376

(UniProtKB/Swiss-Prot/P) Details

Calcium-binding protein 39

A0A1W2PPJ9

Interaction Score

0.926

P48426

(UniProtKB/Swiss-Prot/P) Details

Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.79	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Autophagic vacuole (GO:0005776)	0.998	Experimental: inferred from mutant phenotype	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A1W2PPJ9

Interaction Score

0.896

Q14568

(UniProtKB/Swiss-Prot/P) Details

Heat shock protein HSP 90-alpha A2

A0A1W2PPJ9

Interaction Score

0.806

Q86SX1

(UniProtKB/TrEmbl/P) Details

Full-length cDNA 5-PRIME end of clone CS0DN005YI08 of Adult brain of Homo sapiens

A0A1W2PPJ9

Interaction Score

0.786

Q7Z6I8

(UniProtKB/Swiss-Prot/P) Details

UPF0461 protein C5orf24

A0A1W2PPJ9

Interaction Score

0.766

Q9H9S4

(UniProtKB/Swiss-Prot/P) Details

Calcium-binding protein 39-like

A0A1W2PPJ9

Interaction Score

0.64

H3BVB1

(UniProtKB/TrEmbl/P) Details

F-box/LRR-repeat protein 19

A0A1W2PPJ9

Interaction Score

0.56

Q5BJF5

(UniProtKB/TrEmbl/P) Details

Serine hydroxymethyltransferase

A0A1W2PPJ9

Interaction Score

Q5HYG8

(UniProtKB/TrEmbl/P) Details

Serine hydroxymethyltransferase

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A0A1W2PPJ9

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

A0A1W2PPJ9

O14980

Exportin-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A1W2PPJ9

Q15831

Serine/threonine-protein kinase STK11

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A1W2PPJ9

P34897

Serine hydroxymethyltransferase, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A1W2PPJ9

P07900

Heat shock protein HSP 90-alpha

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A1W2PPJ9

Q9BQE6

LBH domain-containing protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A1W2PPJ9

Q6PCT2

F-box/LRR-repeat protein 19

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A1W2PPJ9

Q9Y376

Calcium-binding protein 39

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A1W2PPJ9

P48426

Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A1W2PPJ9

Q14568

Heat shock protein HSP 90-alpha A2

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A1W2PPJ9

Q86SX1

Full-length cDNA 5-PRIME end of clone CS0DN005YI08 of Adult brain of Homo sapiens

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A1W2PPJ9

Q7Z6I8

UPF0461 protein C5orf24

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A1W2PPJ9

Q9H9S4

Calcium-binding protein 39-like

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A1W2PPJ9