A0A286YEW8

Major facilitator superfamily domain-containing protein 8 // UniProt Profile

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Species	H. sapiens
Number of Interactions	27 / 39
Average Interaction Score	0.46

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

A0A286YEW8

Interaction Score

0.959

Q9H8X2

(UniProtKB/Swiss-Prot/P) Details

Inositol-pentakisphosphate 2-kinase

A0A286YEW8

Interaction Score

0.942

Q16849

(UniProtKB/Swiss-Prot/P) Details

Receptor-type tyrosine-protein phosphatase-like N

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.958	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Perikaryon (GO:0043204)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Secretory granule (GO:0030141)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Synaptic vesicle (GO:0008021)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Transport vesicle membrane (GO:0030658)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Nerve terminal (GO:0043679)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Vesicle (GO:0031982)	0.958	Experimental: experimental	eSLDB	PubMed
Membrane	Cell junction (GO:0030054)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Synapse (GO:0045202)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A286YEW8

Interaction Score

0.916

Q9GZM5

(UniProtKB/Swiss-Prot/P) Details

Protein YIPF3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: experimental	eSLDB	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Transport vesicle (GO:0030133)	0.998	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.853	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.853	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A286YEW8

Interaction Score

0.916

Q8IZF4

(UniProtKB/Swiss-Prot/P) Details

Adhesion G-protein coupled receptor G5

A0A286YEW8

Interaction Score

0.842

Q15125

(UniProtKB/Swiss-Prot/P) Details

3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nuclear envelope (GO:0005635)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Peroxisome (GO:0005777)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.958	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.958	Experimental: experimental	Organelle	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.958	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A286YEW8

Interaction Score

0.824

Q92633

(UniProtKB/Swiss-Prot/P) Details

Lysophosphatidic acid receptor 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endocytic vesicle (GO:0030139)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendritic shaft (GO:0043198)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A286YEW8

Interaction Score

0.788

Q9UHQ9

(UniProtKB/Swiss-Prot/P) Details

NADH-cytochrome b5 reductase 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.956	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.902	Unknown: unspecified method	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.51	Unknown: HDA	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.51	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	0.3	Unknown: unspecified method	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.956	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.956	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Platelet alpha granule membrane (GO:0031092)	0.956	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.902	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.657	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.657	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.902	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A286YEW8

Interaction Score

0.75

P01909

(UniProtKB/Swiss-Prot/P) Details

HLA class II histocompatibility antigen, DQ alpha 1 chain

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.983	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.937	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Integral to lumenal side of endoplasmic reticulum membrane (GO:0071556)	0.983	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.983	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Trans-Golgi network membrane (GO:0032588)	0.983	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.983	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	0.937	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endocytic vesicle membrane (GO:0030666)	0.983	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	ER to Golgi transport vesicle membrane (GO:0012507)	0.983	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Clathrin-coated endocytic vesicle membrane (GO:0030669)	0.983	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Transport vesicle membrane (GO:0030658)	0.983	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	0.996	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.996	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Experimental: experimental	Organelle	PubMed
Membrane	MHC class II protein complex (GO:0042613)	0.996	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.996	Unknown: non-traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A286YEW8

Interaction Score

0.728

P25090

(UniProtKB/Swiss-Prot/P) Details

N-formyl peptide receptor 2

A0A286YEW8

Interaction Score

0.688

P48960

(UniProtKB/Swiss-Prot/P) Details

CD97 antigen

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.86	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Secretory granule membrane (GO:0030667)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.988	Experimental: experimental	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.988	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	0.998	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.998	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.998	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: experimental	Organelle	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.998	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.86	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.998	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A286YEW8

Interaction Score

0.64

H9NIL4

(UniProtKB/TrEmbl/P) Details

G protein-coupled receptor 21

A0A286YEW8

Interaction Score

0.64

Q86W33

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein adipocyte-associated 1

A0A286YEW8

Interaction Score

0.64

Q96DA6

(UniProtKB/Swiss-Prot/P) Details

Mitochondrial import inner membrane translocase subunit TIM14

A0A286YEW8

Interaction Score

0.64

Q96IA0

(UniProtKB/TrEmbl/P) Details

PTPRN protein

A0A286YEW8

Interaction Score

0.64

P07307

(UniProtKB/Swiss-Prot/P) Details

Asialoglycoprotein receptor 2

A0A286YEW8

Interaction Score

0.64

P43119

(UniProtKB/Swiss-Prot/P) Details

Prostacyclin receptor

A0A286YEW8

Interaction Score

0.24

P07099

(UniProtKB/Swiss-Prot/P) Details

Epoxide hydrolase 1

A0A286YEW8

Interaction Score

Q401N2

(UniProtKB/Swiss-Prot/P) Details

Zinc-activated ligand-gated ion channel

A0A286YEW8

Interaction Score

Q99679

(UniProtKB/Swiss-Prot/P) Details

Probable G-protein coupled receptor 21

A0A286YEW8

Interaction Score

Q16581

(UniProtKB/Swiss-Prot/P) Details

C3a anaphylatoxin chemotactic receptor

A0A286YEW8

Interaction Score

Q86VW1

(UniProtKB/Swiss-Prot/P) Details

Solute carrier family 22 member 16

A0A286YEW8

Interaction Score

Q7Z4G9

(UniProtKB/TrEmbl/P) Details

HBxAg-binding protein

A0A286YEW8

Interaction Score

P32971

(UniProtKB/Swiss-Prot/P) Details

Tumor necrosis factor ligand superfamily member 8

A0A286YEW8

Interaction Score

Q5VZX0

(UniProtKB/TrEmbl/P) Details

Endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2, isoform CRA_a

A0A286YEW8

Interaction Score

R4SBI6

(UniProtKB/TrEmbl/P) Details

Epoxide hydrolase

A0A286YEW8

Interaction Score

Q9H244

(UniProtKB/Swiss-Prot/P) Details

P2Y purinoceptor 12

A0A286YEW8

Interaction Score

Q8IVM8

(UniProtKB/Swiss-Prot/P) Details

Solute carrier family 22 member 9

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A0A286YEW8

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

A0A286YEW8

Q9H8X2

Inositol-pentakisphosphate 2-kinase

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A286YEW8

Q16849

Receptor-type tyrosine-protein phosphatase-like N

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A286YEW8

Q9GZM5

Protein YIPF3

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A286YEW8

Q8IZF4

Adhesion G-protein coupled receptor G5

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A286YEW8

Q15125

3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A286YEW8

Q92633

Lysophosphatidic acid receptor 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A286YEW8

Q9UHQ9

NADH-cytochrome b5 reductase 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A286YEW8

P01909

HLA class II histocompatibility antigen, DQ alpha 1 chain

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A286YEW8

P25090

N-formyl peptide receptor 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A286YEW8

P48960

CD97 antigen

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A286YEW8

H9NIL4

G protein-coupled receptor 21

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A286YEW8

Q86W33

Transmembrane protein adipocyte-associated 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A286YEW8