G5EDL3

Aurora/Ipl1 Related kinase    //   UniProt Profile 

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Species

 C. elegans

Number of Interactions

 20 / 24

Average Interaction Score

 0.73

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Astral microtubule (GO:0000235) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Spindle midzone (GO:0051233) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Kinetochore microtubule (GO:0005828) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Spindle pole centrosome (GO:0031616) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Chromosome passenger complex (GO:0032133) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Condensed nuclear chromosome (GO:0000794) 0.94 Experimental: inferred from direct assay GO PubMed 
Nucleus Condensed nuclear chromosome, centromeric region (GO:0000780) 0.94 Predicted: inferred from biological aspect of ancestor GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

G5EDL3

Interaction Score
1

P91349

(UniProtKB/Swiss-Prot/P) Details

Spindle-defective protein 5

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.998 Experimental: experimental eSLDB PubMed 
Cytosol Centrosome (GO:0005813) 0.998 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed , PubMed 

G5EDL3

Interaction Score
1

G5EDE7

(UniProtKB/TrEmbl/P) Details

TPX2 (Targeting Protein for Xenopus Klp2)-Like

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Astral microtubule (GO:0000235) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Meiotic spindle (GO:0072687) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Spindle pole centrosome (GO:0031616) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule (GO:0005874) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

G5EDL3

Interaction Score
0.999

Q9NGT3

(UniProtKB/TrEmbl/P) Details

MAD (Yeast Mitosis arrest DeFicient) related

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Pronucleus (GO:0045120) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Spindle midzone (GO:0051233) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 0.988 Experimental: inferred from direct assay GO PubMed 
Nucleus Condensed nuclear chromosome kinetochore (GO:0000778) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Condensed chromosome kinetochore (GO:0000777) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

G5EDL3

Interaction Score
0.995

Q22053

(UniProtKB/Swiss-Prot/P) Details

rRNA 2'-O-methyltransferase fibrillarin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Box C/D snoRNP complex (GO:0031428) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Small-subunit processome (GO:0032040) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleolus (GO:0005730) 0.999 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.999 Experimental: inferred from direct assay GO PubMed 
Nucleus Cajal body (GO:0015030) 0.999 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

G5EDL3

Interaction Score
0.992

B2D6K9

(UniProtKB/TrEmbl/P) Details

SAPS (Phosphatase associated) domain protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Cell cortex (GO:0005938) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Astral microtubule (GO:0000235) 0.992 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

G5EDL3

Interaction Score
0.98

P34766

(UniProtKB/Swiss-Prot/P) Details

Homeobox protein pal-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Condensed nuclear chromosome (GO:0000794) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Condensed chromosome kinetochore (GO:0000777) 0.992 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

G5EDL3

Interaction Score
0.96

G5ED84

(UniProtKB/Swiss-Prot/P) Details

Kelch-like protein 8

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cul3-RING ubiquitin ligase complex (GO:0031463) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Neuronal cell body (GO:0043025) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Neuron projection (GO:0043005) 0.972 Experimental: inferred from direct assay GO PubMed 
Membrane Postsynaptic density (GO:0014069) 0.972 Experimental: inferred from direct assay GO PubMed 
Membrane Cell junction (GO:0030054) 0.972 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

G5EDL3

Interaction Score
0.932

G5EE37

(UniProtKB/TrEmbl/P) Details

InCenP homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Chromosome (GO:0005694) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Kinetochore (GO:0000776) 0.992 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

G5EDL3

Interaction Score
0.7

Q21747

(UniProtKB/TrEmbl/P) Details

BTB/POZ Domain-containing protein homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

G5EDL3

Interaction Score
0.7

Q8WSN6

(UniProtKB/TrEmbl/P) Details

TPX2 (Targeting Protein for Xenopus Klp2)-Like

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

G5EDL3

Interaction Score
0.7

O61900

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

G5EDL3

Interaction Score
0.7

Q21748

(UniProtKB/TrEmbl/P) Details

BTB/POZ Domain-containing protein homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

G5EDL3

Interaction Score
0.658

O45335

(UniProtKB/TrEmbl/P) Details

F-box A protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

G5EDL3

Interaction Score
0.658

Q18696

(UniProtKB/TrEmbl/P) Details

SAPS (Phosphatase associated) domain protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

G5EDL3

Interaction Score
0.658

P41886

(UniProtKB/Swiss-Prot/P) Details

BTB and MATH domain-containing protein 41

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

G5EDL3

Interaction Score
0.658

Q8T870

(UniProtKB/TrEmbl/P) Details

MAD (Yeast Mitosis arrest DeFicient) related

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

G5EDL3

Interaction Score
0.658

Q86NF2

(UniProtKB/TrEmbl/P) Details

BTB/POZ Domain-containing protein homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

G5EDL3

Interaction Score
0.658

Q7JP41

(UniProtKB/TrEmbl/P) Details

BTB/POZ Domain-containing protein homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

G5EDL3

Interaction Score
0

O76665

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

G5EDL3

Interaction Score
0

L8E7Y1

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Integral to membrane (GO:0016021) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015