O15444

C-C motif chemokine 25 // UniProt Profile

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Species	H. sapiens
Number of Interactions	13 / 13
Average Interaction Score	0.959

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.937	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.937	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

O15444

Interaction Score

0.995

P04217

(UniProtKB/Swiss-Prot/P) Details

Alpha-1B-glycoprotein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.981	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.987	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.987	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Lysosome (GO:0005764)	0.981	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Peroxisome (GO:0005777)	0.981	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.987	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Platelet alpha granule lumen (GO:0031093)	0.987	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.994	Unknown: HDA	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.994	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.994	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.994	Unknown: HDA	GO	PubMed
Extracellular	Blood microparticle (GO:0072562)	0.994	Unknown: HDA	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.994	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.94	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.94	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.981	Unknown: HDA	GO	PubMed

Interaction Source Database:

DIP

Interaction Source Publication:

PubMed

O15444

Interaction Score

0.99

P02776

(UniProtKB/Swiss-Prot/P) Details

Platelet factor 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.86	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Platelet alpha granule lumen (GO:0031093)	0.86	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.992	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.996	Unknown: non-traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.996	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Symbiont-containing vacuole membrane (GO:0020005)	0.996	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular space (GO:0005615)	0.996	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O15444

Interaction Score

0.987

O14625

(UniProtKB/Swiss-Prot/P) Details

C-X-C motif chemokine 11

O15444

Interaction Score

0.986

Q92583

(UniProtKB/Swiss-Prot/P) Details

C-C motif chemokine 17

O15444

Interaction Score

0.986

P10720

(UniProtKB/Swiss-Prot/P) Details

Platelet factor 4 variant

O15444

Interaction Score

0.985

P48061

(UniProtKB/Swiss-Prot/P) Details

Stromal cell-derived factor 1

O15444

Interaction Score

0.983

P46092

(UniProtKB/Swiss-Prot/P) Details

C-C chemokine receptor type 10

O15444

Interaction Score

0.981

P13501

(UniProtKB/Swiss-Prot/P) Details

C-C motif chemokine 5

O15444

Interaction Score

0.968

O00590

(UniProtKB/Swiss-Prot/P) Details

Atypical chemokine receptor 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Recycling endosome (GO:0055037)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin filament (GO:0005884)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.998	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.998	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

O15444

Interaction Score

0.967

Q9NPB9

(UniProtKB/Swiss-Prot/P) Details

Atypical chemokine receptor 4

O15444

Interaction Score

0.954

Q6UXB2

(UniProtKB/Swiss-Prot/P) Details

C-X-C motif chemokine 17

O15444

Interaction Score

0.95

P51686

(UniProtKB/Swiss-Prot/P) Details

C-C chemokine receptor type 9

O15444

Interaction Score

0.741

Q8TB22

(UniProtKB/Swiss-Prot/P) Details

Spermatogenesis-associated protein 20

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O15444

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

O15444

P04217

Alpha-1B-glycoprotein

Localizations:

Interaction Source Database:

Interaction Source Publication:

O15444

P02776

Platelet factor 4

Localizations:

Interaction Source Database:

Interaction Source Publication:

O15444

O14625

C-X-C motif chemokine 11

Localizations:

Interaction Source Database:

Interaction Source Publication:

O15444

Q92583

C-C motif chemokine 17

Localizations:

Interaction Source Database:

Interaction Source Publication:

O15444

P10720

Platelet factor 4 variant

Localizations:

Interaction Source Database:

Interaction Source Publication:

O15444

P48061

Stromal cell-derived factor 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O15444

P46092

C-C chemokine receptor type 10

Localizations:

Interaction Source Database:

Interaction Source Publication:

O15444

P13501

C-C motif chemokine 5

Localizations:

Interaction Source Database:

Interaction Source Publication:

O15444

O00590

Atypical chemokine receptor 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

O15444

Q9NPB9

Atypical chemokine receptor 4

Localizations:

Interaction Source Database:

Interaction Source Publication:

O15444

Q6UXB2

C-X-C motif chemokine 17

Localizations:

Interaction Source Database:

Interaction Source Publication:

O15444

P51686

C-C chemokine receptor type 9

Localizations:

Interaction Source Database:

Interaction Source Publication:

O15444