O60595

Interleukin-12 subunit alpha // UniProt Profile

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Species	H. sapiens
Number of Interactions	7 / 7
Average Interaction Score	0.843

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

O60595

Interaction Score

0.967

P29460

(UniProtKB/Swiss-Prot/P) Details

Interleukin-12 subunit beta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.86	Experimental: experimental	eSLDB	PubMed
Membrane	Cell surface (GO:0009986)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.3	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.999	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.999	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.999	Unknown: traceable author statement	GO	PubMed
Extracellular	Interleukin-12 complex (GO:0043514)	0.999	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Interleukin-23 complex (GO:0070743)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane (GO:0016020)	0.902	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O60595

Interaction Score

0.963

P20337

(UniProtKB/Swiss-Prot/P) Details

Ras-related protein Rab-3B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.853	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Secretory granule (GO:0030141)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.992	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Vesicle (GO:0031982)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O60595

Interaction Score

0.951

Q05707

(UniProtKB/Swiss-Prot/P) Details

Collagen alpha-1(XIV) chain

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	0.79	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.96	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.99	Unknown: HDA	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.99	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.99	Unknown: HDA	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.99	Unknown: non-traceable author statement	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.99	Experimental: experimental	MatrixDB	PubMed
Extracellular	Collagen (GO:0005581)	0.99	Unknown: non-traceable author statement	GO	PubMed
Extracellular	Collagen type XIV (GO:0005596)	0.99	Unknown: non-traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O60595

Interaction Score

0.946

Q9Y624

(UniProtKB/Swiss-Prot/P) Details

Junctional adhesion molecule A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.994	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.994	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.994	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell-cell junction (GO:0005911)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Slit diaphragm (GO:0036057)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Tight junction (GO:0005923)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O60595

Interaction Score

0.942

Q12841

(UniProtKB/Swiss-Prot/P) Details

Follistatin-related protein 1

O60595

Interaction Score

0.64

Q6FIB4

(UniProtKB/TrEmbl/P) Details

F11 receptor

O60595

Interaction Score

0.49

Q96EA4

(UniProtKB/Swiss-Prot/P) Details

Protein Spindly

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O60595

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

O60595

P29460

Interleukin-12 subunit beta

Localizations:

Interaction Source Database:

Interaction Source Publication:

O60595

P20337

Ras-related protein Rab-3B

Localizations:

Interaction Source Database:

Interaction Source Publication:

O60595

Q05707

Collagen alpha-1(XIV) chain

Localizations:

Interaction Source Database:

Interaction Source Publication:

O60595

Q9Y624

Junctional adhesion molecule A

Localizations:

Interaction Source Database:

Interaction Source Publication:

O60595

Q12841

Follistatin-related protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O60595

Q6FIB4

F11 receptor

Localizations:

Interaction Source Database:

Interaction Source Publication:

O60595

Q96EA4

Protein Spindly

Localizations:

Interaction Source Database:

Interaction Source Publication: