O75783

Rhomboid-related protein 1 // UniProt Profile

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Species	H. sapiens
Number of Interactions	15 / 18
Average Interaction Score	0.815

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.971	Unknown: traceable author statement	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.971	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.971	Experimental: experimental	Organelle	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.971	Unknown: traceable author statement	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

O75783

Interaction Score

0.997

Q86UL8

(UniProtKB/Swiss-Prot/P) Details

Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.982	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.982	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.982	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.94	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendrite (GO:0030425)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Slit diaphragm (GO:0036057)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Tight junction (GO:0005923)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Synapse (GO:0045202)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O75783

Interaction Score

0.996

Q9H0Q3

(UniProtKB/Swiss-Prot/P) Details

FXYD domain-containing ion transport regulator 6

O75783

Interaction Score

0.995

Q92796

(UniProtKB/Swiss-Prot/P) Details

Disks large homolog 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	0.956	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.956	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.956	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.956	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Growth cone (GO:0030426)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic shaft (GO:0043198)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular space (GO:0005615)	0.3	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Ionotropic glutamate receptor complex (GO:0008328)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex (GO:0032281)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Basolateral plasma membrane (GO:0016323)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Tight junction (GO:0005923)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O75783

Interaction Score

0.994

Q5TCQ9

(UniProtKB/Swiss-Prot/P) Details

Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3

O75783

Interaction Score

0.993

P26012

(UniProtKB/Swiss-Prot/P) Details

Integrin beta-8

O75783

Interaction Score

0.988

P21964

(UniProtKB/Swiss-Prot/P) Details

Catechol O-methyltransferase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cell body (GO:0044297)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Lysosome (GO:0005764)	0.999	Predicted: pTarget method	LOCATE	PubMed
Membrane	Dendritic spine (GO:0043197)	0.976	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	0.976	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	eSLDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.976	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.976	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.976	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.976	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	0.976	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O75783

Interaction Score

0.987

P05090

(UniProtKB/Swiss-Prot/P) Details

Apolipoprotein D

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.94	Experimental: experimental	eSLDB	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.987	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosolic ribosome (GO:0022626)	0.987	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.987	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.94	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.988	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.853	Unknown: non-traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.853	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.853	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.988	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.987	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O75783

Interaction Score

0.92

Q9BUG9

(UniProtKB/TrEmbl/P) Details

Integrin beta

O75783

Interaction Score

0.916

Q969W0

(UniProtKB/Swiss-Prot/P) Details

Serine palmitoyltransferase small subunit A

O75783

Interaction Score

0.916

O95870

(UniProtKB/Swiss-Prot/P) Details

Protein ABHD16A

O75783

Interaction Score

0.842

Q08AM6

(UniProtKB/Swiss-Prot/P) Details

Protein VAC14 homolog

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.992	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.952	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.952	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Late endosome membrane (GO:0031902)	0.952	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.952	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.952	Experimental: inferred from direct assay	GO	PubMed
Cytosol	PAS complex (GO:0070772)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O75783

Interaction Score

0.56

P0C7H8

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 2-3

O75783

Interaction Score

0.56

P60410

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 10-8

O75783

Interaction Score

0.56

Q15034

(UniProtKB/Swiss-Prot/P) Details

Probable E3 ubiquitin-protein ligase HERC3

O75783

Interaction Score

Q59FY1

(UniProtKB/TrEmbl/P) Details

Synapse-associated protein 102 variant

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O75783

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

O75783

Q86UL8

Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75783

Q9H0Q3

FXYD domain-containing ion transport regulator 6

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75783

Q92796

Disks large homolog 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75783

Q5TCQ9

Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75783

P26012

Integrin beta-8

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75783

P21964

Catechol O-methyltransferase

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75783

P05090

Apolipoprotein D

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75783

Q9BUG9

Integrin beta

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75783

Q969W0

Serine palmitoyltransferase small subunit A

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75783

O95870

Protein ABHD16A

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75783

Q08AM6

Protein VAC14 homolog

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75783

P0C7H8

Keratin-associated protein 2-3

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75783