O76447

HoloCentric chromosome binding Protein    //   UniProt Profile 

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Species

 C. elegans

Number of Interactions

 10 / 10

Average Interaction Score

 0.85

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Spindle (GO:0005819) 0.94 Experimental: inferred from direct assay GO PubMed 
Nucleus Condensed chromosome kinetochore (GO:0000777) 0.998 Experimental: inferred from direct assay GO PubMed 
Nucleus Kinetochore (GO:0000776) 0.998 Experimental: inferred from direct assay GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

O76447

Interaction Score
1

P32744

(UniProtKB/Swiss-Prot/P) Details

Protein CLASP-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Mitotic spindle (GO:0072686) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Spindle midzone (GO:0051233) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule (GO:0005874) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Condensed chromosome kinetochore (GO:0000777) 0.992 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Kinetochore (GO:0000776) 0.992 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O76447

Interaction Score
0.998

Q09601

(UniProtKB/Swiss-Prot/P) Details

Nucleoporin NUP35

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nuclear membrane (GO:0031965) 0.997 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nuclear envelope (GO:0005635) 0.997 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear pore (GO:0005643) 0.997 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear pore central transport channel (GO:0044613) 0.997 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nuclear pore nuclear basket (GO:0044615) 0.997 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed , PubMed 

O76447

Interaction Score
0.998

O45717

(UniProtKB/Swiss-Prot/P) Details

Protein nud-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.992 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.992 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nuclear envelope (GO:0005635) 0.94 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Kinesin complex (GO:0005871) 0.992 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Centrosome (GO:0005813) 0.992 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Kinetochore (GO:0000776) 0.94 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Synapse (GO:0045202) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

CCSB, IntAct, BioGRID

Interaction Source Publication:

PubMed , PubMed , PubMed 

O76447

Interaction Score
0.992

P34371

(UniProtKB/Swiss-Prot/P) Details

BTB and MATH domain-containing protein 42

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol SCF ubiquitin ligase complex (GO:0019005) 0.973 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.973 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.973 Predicted: inferred from biological aspect of ancestor GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

CCSB, IntAct, DIP, BioGRID

Interaction Source Publication:

PubMed , PubMed 

O76447

Interaction Score
0.979

Q22257

(UniProtKB/TrEmbl/P) Details

HoloCentric chromosome binding Protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Kinetochore (GO:0000776) 0.94 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O76447

Interaction Score
0.931

Q27365

(UniProtKB/Swiss-Prot/P) Details

Protein lin-15A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct, CCSB

Interaction Source Publication:

PubMed , PubMed 

O76447

Interaction Score
0.76

Q27395

(UniProtKB/Swiss-Prot/P) Details

Protein lin-15B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
N/A Cellular component (GO:0005575) 0.3 Unknown: no biological data available GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: non-traceable author statement GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O76447

Interaction Score
0.752

P48181

(UniProtKB/Swiss-Prot/P) Details

Acetylcholine receptor subunit beta-type unc-29

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Neuronal cell body (GO:0043025) 0.8 Experimental: inferred from direct assay GO PubMed 
Membrane Neuron projection (GO:0043005) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Cell junction (GO:0030054) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Synapse (GO:0045202) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Postsynaptic membrane (GO:0045211) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

O76447

Interaction Score
0.658

Q11189

(UniProtKB/Swiss-Prot/P) Details

28S ribosomal protein S17, mitochondrial

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrial small ribosomal subunit (GO:0005763) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

DIP, IntAct, BioGRID, CCSB

Interaction Source Publication:

PubMed , PubMed 

O76447

Interaction Score
0.433

O44782

(UniProtKB/TrEmbl/P) Details

Major sperm protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID, DIP, IntAct, CCSB

Interaction Source Publication:

PubMed , PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015