P09446

Heat shock 70 kDa protein A    //   UniProt Profile 

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Species

 C. elegans

Number of Interactions

 11 / 12

Average Interaction Score

 0.734

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.988 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: inferred from direct assay GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

P09446

Interaction Score
0.997

Q18688

(UniProtKB/Swiss-Prot/P) Details

Heat shock protein 90

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.998 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.998 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: experimental eSLDB PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane raft (GO:0045121) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P09446

Interaction Score
0.981

O16259

(UniProtKB/Swiss-Prot/P) Details

Stress-induced-phosphoprotein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P09446

Interaction Score
0.961

Q23356

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase mig-15

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.973 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.973 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.973 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct, DIP, BioGRID

Interaction Source Publication:

PubMed 

P09446

Interaction Score
0.956

Q9GZH5

(UniProtKB/TrEmbl/P) Details

26S proteasome non-ATPase regulatory subunit 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Proteasome storage granule (GO:0034515) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Proteasome regulatory particle, base subcomplex (GO:0008540) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed , PubMed 

P09446

Interaction Score
0.948

G5EG62

(UniProtKB/TrEmbl/P) Details

UNC-45

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cleavage furrow (GO:0032154) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Cell cortex (GO:0005938) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P09446

Interaction Score
0.79

G5ECY6

(UniProtKB/TrEmbl/P) Details

C-term of Hsp70-iNteracting protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.8 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P09446

Interaction Score
0.766

O45521

(UniProtKB/Swiss-Prot/P) Details

Nuclear hormone receptor family member nhr-111

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.958 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

DIP, IntAct, BioGRID

Interaction Source Publication:

PubMed 

P09446

Interaction Score
0.692

O44739

(UniProtKB/Swiss-Prot/P) Details

BAG family molecular chaperone regulator 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

DIP, IntAct, BioGRID, CCSB

Interaction Source Publication:

PubMed , PubMed 

P09446

Interaction Score
0.692

O17253

(UniProtKB/TrEmbl/P) Details

BTB (Broad/complex/Tramtrack/Bric a brac) domain protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct, CCSB

Interaction Source Publication:

PubMed 

P09446

Interaction Score
0.296

G5ED36

(UniProtKB/TrEmbl/P) Details

Endocytosis protein RME-8

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Recycling endosome (GO:0055037) 0.998 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Early endosome (GO:0005769) 0.998 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Late endosome (GO:0005770) 0.998 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.998 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

P09446

Interaction Score
0

G5EGG0

(UniProtKB/TrEmbl/P) Details

USO1 (Yeast transport protein) homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.981 Predicted: inferred from biological aspect of ancestor GO PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.981 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Golgi stack (GO:0005795) 0.981 Predicted: inferred from biological aspect of ancestor GO PubMed 
Secretory-pathway ER to Golgi transport vesicle membrane (GO:0012507) 0.981 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015