Q09417

Guanine nucleotide exchange factor subunit R06F6.8    //   UniProt Profile 

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Species

 C. elegans

Number of Interactions

 13 / 16

Average Interaction Score

 0.736

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.7 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.7 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Ric1p-Rgp1p complex (GO:0034066) 0.91 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Membrane (GO:0016020) 0.937 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.937 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.937 Unknown: inferred from electronic annotation GO PubMed 

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Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q09417

Interaction Score
0.992

Q9XX47

(UniProtKB/Swiss-Prot/P) Details

Protein fam-161

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Axoneme (GO:0005930) 0.8 Experimental: inferred from direct assay GO PubMed 
Membrane Ciliary base (GO:0097546) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Ciliary transition zone (GO:0035869) 0.96 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct, DIP, BioGRID

Interaction Source Publication:

PubMed 

Q09417

Interaction Score
0.971

Q22227

(UniProtKB/Swiss-Prot/P) Details

Segment polarity protein dishevelled homolog mig-5

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.996 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cell cortex (GO:0005938) 0.996 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Membrane Cell junction (GO:0030054) 0.51 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

DIP, IntAct, BioGRID

Interaction Source Publication:

PubMed 

Q09417

Interaction Score
0.878

Q8ITY3

(UniProtKB/TrEmbl/P) Details

Gamma-tubulin complex component

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.76 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Spindle pole (GO:0000922) 0.76 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Microtubule organizing center (GO:0005815) 0.76 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Microtubule (GO:0005874) 0.76 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q09417

Interaction Score
0.837

P34334

(UniProtKB/Swiss-Prot/P) Details

60S ribosomal protein L21

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.973 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.973 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosolic large ribosomal subunit (GO:0022625) 0.973 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID, DIP, IntAct

Interaction Source Publication:

PubMed 

Q09417

Interaction Score
0.815

P91505

(UniProtKB/TrEmbl/P) Details

Glutathione S-Transferase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID, IntAct, DIP

Interaction Source Publication:

PubMed 

Q09417

Interaction Score
0.815

Q22664

(UniProtKB/TrEmbl/P) Details

Chromosome Transmission Fidelity factor homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Ctf18 RFC-like complex (GO:0031390) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID, IntAct, DIP

Interaction Source Publication:

PubMed 

Q09417

Interaction Score
0.776

Q27365

(UniProtKB/Swiss-Prot/P) Details

Protein lin-15A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct, CCSB

Interaction Source Publication:

PubMed , PubMed 

Q09417

Interaction Score
0.772

P37165

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-like protein 1-40S ribosomal protein S27a

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
N/A Cellular component (GO:0005575) 0.3 Unknown: no biological data available GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Ribosome (GO:0005840) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct, DIP, BioGRID

Interaction Source Publication:

PubMed 

Q09417

Interaction Score
0.74

O45691

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

DIP, BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q09417

Interaction Score
0.7

Q95QC4

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase zyg-8

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Spindle microtubule (GO:0005876) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Spindle pole (GO:0000922) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

DIP, BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q09417

Interaction Score
0.681

Q95XM4

(UniProtKB/TrEmbl/P) Details

Cyclin-dependent kinases regulatory subunit

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol SCF ubiquitin ligase complex (GO:0019005) 0.973 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.973 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cyclin-dependent protein kinase holoenzyme complex (GO:0000307) 0.973 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

DIP, BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q09417

Interaction Score
0.597

Q27395

(UniProtKB/Swiss-Prot/P) Details

Protein lin-15B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
N/A Cellular component (GO:0005575) 0.3 Unknown: no biological data available GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: non-traceable author statement GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q09417

Interaction Score
0

O61208

(UniProtKB/TrEmbl/P) Details

Gamma-tubulin complex component

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

DIP, BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015