Q17390

Cullin-2    //   UniProt Profile 

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Species

 C. elegans

Number of Interactions

 10 / 10

Average Interaction Score

 0.891

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cullin-RING ubiquitin ligase complex (GO:0031461) 0.982 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.982 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 

First-Neighbour Network Visualization

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Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q17390

Interaction Score
0.998

Q23457

(UniProtKB/Swiss-Prot/P) Details

RING-box protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cul7-RING ubiquitin ligase complex (GO:0031467) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cul3-RING ubiquitin ligase complex (GO:0031463) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cul2-RING ubiquitin ligase complex (GO:0031462) 1 Predicted: inferred from physical interaction GO PubMed 
Cytosol CUL4 RING ubiquitin ligase complex (GO:0080008) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Nuclear SCF ubiquitin ligase complex (GO:0043224) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q17390

Interaction Score
0.992

P17221

(UniProtKB/Swiss-Prot/P) Details

Sex-determining protein fem-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cul2-RING ubiquitin ligase complex (GO:0031462) 0.987 Predicted: inferred from physical interaction GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.987 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.987 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.8 Experimental: inferred from mutant phenotype GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q17390

Interaction Score
0.985

Q9BKS1

(UniProtKB/TrEmbl/P) Details

ELongin C

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cul2-RING ubiquitin ligase complex (GO:0031462) 0.91 Predicted: inferred from physical interaction GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Elongin complex (GO:0070449) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q17390

Interaction Score
0.975

P34708

(UniProtKB/Swiss-Prot/P) Details

Sex-determining transformer protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.8 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q17390

Interaction Score
0.974

Q19988

(UniProtKB/TrEmbl/P) Details

Leucine-Rich Repeat protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cul2-RING ubiquitin ligase complex (GO:0031462) 0.79 Unknown: inferred by curator GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q17390

Interaction Score
0.964

G5ECR7

(UniProtKB/TrEmbl/P) Details

ELongin B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol VCB complex (GO:0030891) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cul2-RING ubiquitin ligase complex (GO:0031462) 0.91 Predicted: inferred from physical interaction GO PubMed 
Nucleus Elongin complex (GO:0070449) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q17390

Interaction Score
0.894

Q19213

(UniProtKB/Swiss-Prot/P) Details

von Hippel-Lindau tumor suppressor homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cul2-RING ubiquitin ligase complex (GO:0031462) 0.91 Predicted: inferred from physical interaction GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q17390

Interaction Score
0.752

G5ED41

(UniProtKB/Swiss-Prot/P) Details

Cullin-associated NEDD8-dissociated protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.8 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q17390

Interaction Score
0.687

P21541

(UniProtKB/Swiss-Prot/P) Details

Early embryogenesis protein zyg-11

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cul2-RING ubiquitin ligase complex (GO:0031462) 0.7 Predicted: inferred from physical interaction GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q17390

Interaction Score
0.687

Q2WF59

(UniProtKB/Swiss-Prot/P) Details

Zyg eleven-related protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cul2-RING ubiquitin ligase complex (GO:0031462) 0.7 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015