Q19207

3-hydroxy-3-methylglutaryl coenzyme A reductase    //   UniProt Profile 

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Species

C. elegans

Number of Interactions

4 / 5

Average Interaction Score

0.78

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Peroxisomal membrane (GO:0005778) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.3 Unknown: inferred from electronic annotation GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q19207

Interaction Score
0.904

P34475

(UniProtKB/Swiss-Prot/P) Details

Tubulin gamma chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.98 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 0.98 Experimental: inferred from direct assay GO PubMed 
Cytosol Gamma-tubulin complex (GO:0000930) 0.98 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Microtubule (GO:0005874) 0.98 Unknown: inferred from electronic annotation GO PubMed 
Membrane Hemidesmosome (GO:0030056) 0.51 Unknown: inferred from electronic annotation GO PubMed 
Membrane Adherens junction (GO:0005912) 0.51 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, DIP, IntAct

Interaction Source Publication:

PubMed 

Q19207

Interaction Score
0.847

Q95QC4

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase zyg-8

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Microtubule cytoskeleton (GO:0015630) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Spindle microtubule (GO:0005876) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Spindle pole (GO:0000922) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

Q19207

Interaction Score
0.698

Q22799

(UniProtKB/Swiss-Prot/P) Details

Dynein light chain 1, cytoplasmic

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.997 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.997 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.997 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nuclear envelope (GO:0005635) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasmic dynein complex (GO:0005868) 0.997 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Myosin complex (GO:0016459) 0.997 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Microtubule (GO:0005874) 0.997 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

Q19207

Interaction Score
0.671

Q95005

(UniProtKB/Swiss-Prot/P) Details

Proteasome subunit alpha type-7

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.958 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Proteasome core complex, alpha-subunit complex (GO:0019773) 0.958 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 0.86 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.86 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015