Q19749

Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial    //   UniProt Profile 

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Species

 C. elegans

Number of Interactions

 27 / 37

Average Interaction Score

 0.239

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Pyruvate dehydrogenase complex (GO:0045254) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.992 Experimental: experimental eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.992 Experimental: experimental Organelle PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.992 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrial matrix (GO:0005759) 0.992 Unknown: inferred from electronic annotation GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q19749

Interaction Score
0.986

O44451

(UniProtKB/Swiss-Prot/P) Details

Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.994 Experimental: experimental eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.994 Unknown: HDA GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.994 Experimental: experimental Organelle PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.994 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrial matrix (GO:0005759) 0.994 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q19749

Interaction Score
0.694

Q19955

(UniProtKB/TrEmbl/P) Details

Activator of G protein Signalling

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q19749

Interaction Score
0.3

Q9GSX9

(UniProtKB/Swiss-Prot/P) Details

Synembryn

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cell cortex (GO:0005938) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: experimental eSLDB PubMed 
Cytosol Aster (GO:0005818) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental eSLDB PubMed 
Cytosol Spindle (GO:0005819) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Kinetochore microtubule (GO:0005828) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

CCSB, IntAct, DIP, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q19749

Interaction Score
0.3

G5ECG0

(UniProtKB/Swiss-Prot/P) Details

Transforming acid coiled-coil-containing protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Perikaryon (GO:0043204) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Spindle (GO:0005819) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Spindle pole (GO:0000922) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 0.999 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule (GO:0005874) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Condensed chromosome kinetochore (GO:0000777) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Kinetochore (GO:0000776) 0.86 Experimental: inferred from direct assay GO PubMed 
Membrane Axon (GO:0030424) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

Q19749

Interaction Score
0.299

Q9U9Y8

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine kinase NLK

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cell cortex (GO:0005938) 0.996 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID, DIP, IntAct

Interaction Source Publication:

PubMed 

Q19749

Interaction Score
0.299

Q7JP75

(UniProtKB/TrEmbl/P) Details

CYtoKinesis defect

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cleavage furrow (GO:0032154) 0.996 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Actomyosin contractile ring (GO:0005826) 0.996 Experimental: inferred from direct assay GO PubMed 
Membrane Internal side of plasma membrane (GO:0009898) 0.8 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

Q19749

Interaction Score
0.296

Q23158

(UniProtKB/TrEmbl/P) Details

AcTiniN

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Striated muscle dense body (GO:0055120) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Striated muscle thin filament (GO:0005865) 0.988 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q19749

Interaction Score
0.296

Q9NGT3

(UniProtKB/TrEmbl/P) Details

MAD (Yeast Mitosis arrest DeFicient) related

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Pronucleus (GO:0045120) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Spindle midzone (GO:0051233) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 0.988 Experimental: inferred from direct assay GO PubMed 
Nucleus Condensed nuclear chromosome kinetochore (GO:0000778) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Condensed chromosome kinetochore (GO:0000777) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID, DIP, IntAct

Interaction Source Publication:

PubMed 

Q19749

Interaction Score
0.296

O01761

(UniProtKB/Swiss-Prot/P) Details

Muscle M-line assembly protein unc-89

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol A band (GO:0031672) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol M band (GO:0031430) 0.988 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q19749

Interaction Score
0.295

P10986

(UniProtKB/Swiss-Prot/P) Details

Actin-4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Striated muscle thin filament (GO:0005865) 0.982 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.982 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Membrane raft (GO:0045121) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q19749

Interaction Score
0.273

O18246

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q19749

Interaction Score
0.273

P03949

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein kinase abl-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Extrinsic to internal side of plasma membrane (GO:0031234) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q19749

Interaction Score
0.273

Q20234

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q19749

Interaction Score
0.273

Q965V4

(UniProtKB/TrEmbl/P) Details

EXPOrtin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nuclear envelope (GO:0005635) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q19749

Interaction Score
0.237

O16519

(UniProtKB/Swiss-Prot/P) Details

Gastrulation defective protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cell (GO:0005623) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct, CCSB, BioGRID, DIP

Interaction Source Publication:

PubMed , PubMed 

Q19749

Interaction Score
0.21

Q9XVU8

(UniProtKB/TrEmbl/P) Details

AcTiniN

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

Q19749

Interaction Score
0.21

Q9N5V3

(UniProtKB/TrEmbl/P) Details

IMportin Beta family

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 0.973 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nuclear periphery (GO:0034399) 0.973 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nuclear membrane (GO:0031965) 0.973 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

Q19749

Interaction Score
0.21

Q95ZL1

(UniProtKB/TrEmbl/P) Details

Actin-4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q19749

Interaction Score
0.21

Q6A8K1

(UniProtKB/TrEmbl/P) Details

Actin-4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q19749

Interaction Score
0.21

Q09601

(UniProtKB/Swiss-Prot/P) Details

Nucleoporin NUP35

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nuclear membrane (GO:0031965) 0.997 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nuclear envelope (GO:0005635) 0.997 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear pore (GO:0005643) 0.997 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear pore central transport channel (GO:0044613) 0.997 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nuclear pore nuclear basket (GO:0044615) 0.997 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q19749

Interaction Score
0

Q21443

(UniProtKB/Swiss-Prot/P) Details

Lamin-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.999 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nuclear periphery (GO:0034399) 0.999 Experimental: inferred from direct assay GO PubMed 
Nucleus Lamin filament (GO:0005638) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nuclear inner membrane (GO:0005637) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nuclear envelope (GO:0005635) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q19749

Interaction Score
0

Q18100

(UniProtKB/TrEmbl/P) Details

Sensory AXon guidance

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q19749

Interaction Score
0

Q9N415

(UniProtKB/TrEmbl/P) Details

RIM Binding protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q19749

Interaction Score
0

Q8T870

(UniProtKB/TrEmbl/P) Details

MAD (Yeast Mitosis arrest DeFicient) related

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q19749

Interaction Score
0

P34258

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized protein B0303.7

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q19749

Interaction Score
0

O44797

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q19749

Interaction Score
0

G5EGG0

(UniProtKB/TrEmbl/P) Details

USO1 (Yeast transport protein) homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.981 Predicted: inferred from biological aspect of ancestor GO PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.981 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Golgi stack (GO:0005795) 0.981 Predicted: inferred from biological aspect of ancestor GO PubMed 
Secretory-pathway ER to Golgi transport vesicle membrane (GO:0012507) 0.981 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015