Q45FX5

Protein vav-1    //   UniProt Profile 

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Species

 C. elegans

Number of Interactions

 28 / 34

Average Interaction Score

 0.429

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular (GO:0005622) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q45FX5

Interaction Score
0.79

P39055

(UniProtKB/Swiss-Prot/P) Details

Dynamin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Midbody (GO:0030496) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cleavage furrow (GO:0032154) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Apical part of cell (GO:0045177) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrial membrane (GO:0031966) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 
Secretory-pathway Cytoplasmic vesicle (GO:0031410) 0.972 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Phagocytic vesicle (GO:0045335) 0.972 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Phagocytic vesicle membrane (GO:0030670) 0.972 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental eSLDB PubMed 
Cytosol Spindle microtubule (GO:0005876) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Pseudopodium (GO:0031143) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Periciliary membrane compartment (GO:1990075) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Axon (GO:0030424) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Phagocytic cup (GO:0001891) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Synapse (GO:0045202) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Presynaptic active zone (GO:0048786) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0.781

O01761

(UniProtKB/Swiss-Prot/P) Details

Muscle M-line assembly protein unc-89

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol A band (GO:0031672) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol M band (GO:0031430) 0.988 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0.781

P55956

(UniProtKB/Swiss-Prot/P) Details

Aspartic protease 3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.8 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Lysosome (GO:0005764) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Lysosome (GO:0005764) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular region (GO:0005576) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0.78

P53013

(UniProtKB/Swiss-Prot/P) Details

Elongation factor 1-alpha

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular (GO:0005622) 0.987 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.987 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.987 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct, BioGRID, DIP

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0.776

Q19905

(UniProtKB/Swiss-Prot/P) Details

UDP-glucose 6-dehydrogenase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.982 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.982 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0.743

Q9U1W1

(UniProtKB/TrEmbl/P) Details

TFG related

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.94 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.8 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum exit site (GO:0070971) 0.86 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0.719

Q22847

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

CCSB, IntAct, BioGRID, DIP

Interaction Source Publication:

PubMed , PubMed 

Q45FX5

Interaction Score
0.632

P34708

(UniProtKB/Swiss-Prot/P) Details

Sex-determining transformer protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.8 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0.632

A0A1C3NSL9

(UniProtKB/Swiss-Prot/P) Details

Apical junction molecule

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cilium basal body (GO:0036064) 0.8 Experimental: inferred from direct assay GO PubMed 
Membrane Dendrite terminus (GO:0044292) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Apicolateral plasma membrane (GO:0016327) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Apical junction complex (GO:0043296) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Apical plasma membrane (GO:0016324) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Cell-cell junction (GO:0005911) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Cell-cell adherens junction (GO:0005913) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0.624

A0A0K3AV08

(UniProtKB/Swiss-Prot/P) Details

Mitogen-activated protein kinase kinase kinase mlk-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular (GO:0005622) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0.553

Q9U9C3

(UniProtKB/TrEmbl/P) Details

Homeodomain protein PHP-3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID, CCSB

Interaction Source Publication:

PubMed , PubMed 

Q45FX5

Interaction Score
0.553

O17286

(UniProtKB/TrEmbl/P) Details

Nuclear transcription Factor Y, B (Beta) subunit

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0.553

Q6A573

(UniProtKB/TrEmbl/P) Details

CD2AP homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0.553

Q19275

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Plasma membrane (GO:0005886) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0.553

Q9XW88

(UniProtKB/TrEmbl/P) Details

Posterior Hox gene Paralog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

CCSB, IntAct, DIP, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q45FX5

Interaction Score
0.553

P34766

(UniProtKB/Swiss-Prot/P) Details

Homeobox protein pal-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Condensed nuclear chromosome (GO:0000794) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Condensed chromosome kinetochore (GO:0000777) 0.992 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

CCSB, BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

Q45FX5

Interaction Score
0.553

G5ECL3

(UniProtKB/TrEmbl/P) Details

Pre-RNA processing 21

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol U2 snRNP (GO:0005686) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus U2-type prespliceosome (GO:0071004) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Catalytic step 2 spliceosome (GO:0071013) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0.403

G5EE04

(UniProtKB/TrEmbl/P) Details

Hsp-70 Interacting Protein homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.3 Unknown: HDA GO PubMed 
Cytosol Striated muscle dense body (GO:0055120) 0.51 Unknown: HDA GO PubMed 
Cytosol Sarcomere (GO:0030017) 0.51 Unknown: HDA GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0.237

G5ECK4

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular (GO:0005622) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0.237

Q9N5D3

(UniProtKB/Swiss-Prot/P) Details

Son of sevenless homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular (GO:0005622) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0

G5EDG6

(UniProtKB/TrEmbl/P) Details

COLlagen

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Collagen (GO:0005581) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0

Q9UB01

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0

G5ECL2

(UniProtKB/Swiss-Prot/P) Details

Synaptojanin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Synaptic vesicle (GO:0008021) 0.7 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Cell junction (GO:0030054) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Membrane Synapse (GO:0045202) 0.86 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0

O01634

(UniProtKB/Swiss-Prot/P) Details

Innexin-12

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Integral to membrane (GO:0016021) 0.987 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.987 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.987 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Gap junction (GO:0005921) 0.987 Predicted: inferred from sequence or structural similarity GO PubMed 

Interaction Source Database:

IntAct, DIP, BioGRID

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0

Q22505

(UniProtKB/Swiss-Prot/P) Details

MICOS complex subunit MIC60-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrial inner membrane (GO:0005743) 0.988 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrial proton-transporting ATP synthase complex (GO:0005753) 0.988 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0

O76337

(UniProtKB/Swiss-Prot/P) Details

Cell death protein 6

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Phagocytic vesicle (GO:0045335) 0.8 Experimental: inferred from direct assay GO PubMed 
Membrane Internal side of plasma membrane (GO:0009898) 0.8 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0

O76840

(UniProtKB/Swiss-Prot/P) Details

Papilin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Basement membrane (GO:0005604) 0.94 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q45FX5

Interaction Score
0

Q09967

(UniProtKB/Swiss-Prot/P) Details

LDL receptor repeat-containing protein egg-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endosome membrane (GO:0010008) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.958 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct, DIP, BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015