Q59GJ0

Eukaryotic translation initiation factor 4 gamma, 3 variant // UniProt Profile

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Species	H. sapiens
Number of Interactions	55 / 78
Average Interaction Score	0.406

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: SVM decision tree	eSLDB	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q59GJ0

Interaction Score

0.7

P03372

(UniProtKB/Swiss-Prot/P) Details

Estrogen receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	Transcriptional preinitiation complex (GO:0097550)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Unknown: traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Transcriptionally active chromatin (GO:0035327)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.902	Unknown: non-traceable author statement	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.902	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q59GJ0

Interaction Score

0.7

P49917

(UniProtKB/Swiss-Prot/P) Details

DNA ligase 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Nonhomologous end joining complex (GO:0070419)	0.94	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	DNA ligase IV complex (GO:0032807)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Nucleus	DNA-dependent protein kinase-DNA ligase 4 complex (GO:0005958)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Unknown: inferred by curator	GO	PubMed
Nucleus	Condensed chromosome (GO:0000793)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q59GJ0

Interaction Score

0.7

Q13148

(UniProtKB/Swiss-Prot/P) Details

TAR DNA-binding protein 43

Q59GJ0

Interaction Score

0.7

Q15428

(UniProtKB/Swiss-Prot/P) Details

Splicing factor 3A subunit 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ribonucleoprotein complex (GO:0030529)	0.958	Experimental: experimental	Organelle	PubMed
Cytosol	Small nuclear ribonucleoprotein complex (GO:0030532)	0.958	Unknown: traceable author statement	GO	PubMed
Cytosol	U2 snRNP (GO:0005686)	0.958	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Spliceosomal complex (GO:0005681)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	U2-type prespliceosome (GO:0071004)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Catalytic step 2 spliceosome (GO:0071013)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q59GJ0

Interaction Score

0.7

P14866

(UniProtKB/Swiss-Prot/P) Details

Heterogeneous nuclear ribonucleoprotein L

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Ribonucleoprotein granule (GO:0035770)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q59GJ0

Interaction Score

0.7

Q6PD62

(UniProtKB/Swiss-Prot/P) Details

RNA polymerase-associated protein CTR9 homolog

Q59GJ0

Interaction Score

0.7

Q14694

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase 10

Q59GJ0

Interaction Score

0.7

P17980

(UniProtKB/Swiss-Prot/P) Details

26S proteasome regulatory subunit 6A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytoplasmic mRNA processing body (GO:0000932)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Proteasome complex (GO:0000502)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosolic proteasome complex (GO:0031597)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Proteasome accessory complex (GO:0022624)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Proteasome regulatory particle, base subcomplex (GO:0008540)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear proteasome complex (GO:0031595)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.3	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q59GJ0

Interaction Score

0.7

O43251

(UniProtKB/Swiss-Prot/P) Details

RNA binding protein fox-1 homolog 2

Q59GJ0

Interaction Score

0.7

Q9NRC8

(UniProtKB/Swiss-Prot/P) Details

NAD-dependent protein deacetylase sirtuin-7

Q59GJ0

Interaction Score

0.699

Q04637

(UniProtKB/Swiss-Prot/P) Details

Eukaryotic translation initiation factor 4 gamma 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Polysome (GO:0005844)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytosolic small ribosomal subunit (GO:0022627)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Eukaryotic translation initiation factor 4F complex (GO:0016281)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: inferred from mutant phenotype	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleolus (GO:0005730)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q59GJ0

Interaction Score

0.698

Q9BUB5

(UniProtKB/Swiss-Prot/P) Details

MAP kinase-interacting serine/threonine-protein kinase 1

Q59GJ0

Interaction Score

0.694

P11940

(UniProtKB/Swiss-Prot/P) Details

Polyadenylate-binding protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytoplasmic stress granule (GO:0010494)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Catalytic step 2 spliceosome (GO:0071013)	0.992	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.51	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.51	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q59GJ0

Interaction Score

0.672

Q9Y664

(UniProtKB/Swiss-Prot/P) Details

KICSTOR complex protein kaptin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Stereocilium (GO:0032420)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Filamentous actin (GO:0031941)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	0.96	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q59GJ0

Interaction Score

0.672

P04792

(UniProtKB/Swiss-Prot/P) Details

Heat shock protein beta-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Proteasome complex (GO:0000502)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Z disc (GO:0030018)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Spindle (GO:0005819)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular space (GO:0005615)	0.86	Unknown: HDA	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.98	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.98	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.98	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.98	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q59GJ0

Interaction Score

0.658

Q9UBT1

(UniProtKB/TrEmbl/P) Details

Estrogen receptor

Q59GJ0

Interaction Score

0.658

Q96PZ0

(UniProtKB/Swiss-Prot/P) Details

Pseudouridylate synthase 7 homolog

Q59GJ0

Interaction Score

0.658

P60842

(UniProtKB/Swiss-Prot/P) Details

Eukaryotic initiation factor 4A-I

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Eukaryotic translation initiation factor 4F complex (GO:0016281)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.96	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q59GJ0

Interaction Score

0.658

Q8NCF5

(UniProtKB/Swiss-Prot/P) Details

NFATC2-interacting protein

Q59GJ0

Interaction Score

0.658

Q96HA8

(UniProtKB/Swiss-Prot/P) Details

Protein N-terminal glutamine amidohydrolase

Q59GJ0

Interaction Score

0.658

Q7Z319

(UniProtKB/TrEmbl/P) Details

MAP kinase-interacting serine/threonine-protein kinase 1

Q59GJ0

Interaction Score

0.637

Q96I65

(UniProtKB/TrEmbl/P) Details

Eukaryotic translation initiation factor 4 gamma, 1

Q59GJ0

Interaction Score

0.637

Q14240

(UniProtKB/Swiss-Prot/P) Details

Eukaryotic initiation factor 4A-II

Q59GJ0

Interaction Score

0.602

Q8N490

(UniProtKB/Swiss-Prot/P) Details

Probable hydrolase PNKD

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.998	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.988	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.988	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: experimental	Human Proteinpedia	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q59GJ0

Interaction Score

0.56

Q05DF2

(UniProtKB/TrEmbl/P) Details

SF3A2 protein

Q59GJ0

Interaction Score

0.56

A0A0C4DGV9

(UniProtKB/TrEmbl/P) Details

DNA ligase

Q59GJ0

Interaction Score

0.56

E5RHC2

(UniProtKB/TrEmbl/P) Details

Protein N-terminal glutamine amidohydrolase

Q59GJ0

Interaction Score

0.56

Q96IP4

(UniProtKB/Swiss-Prot/P) Details

Terminal nucleotidyltransferase 5A

Q59GJ0

Interaction Score

0.56

H0Y4W6

(UniProtKB/TrEmbl/P) Details

Estrogen receptor

Q59GJ0

Interaction Score

0.56

P55884

(UniProtKB/Swiss-Prot/P) Details

Eukaryotic translation initiation factor 3 subunit B

Q59GJ0

Interaction Score

0.56

Q13310

(UniProtKB/Swiss-Prot/P) Details

Polyadenylate-binding protein 4

Q59GJ0

Interaction Score

0.49

Q13144

(UniProtKB/Swiss-Prot/P) Details

Translation initiation factor eIF-2B subunit epsilon

Q59GJ0

Interaction Score

0.49

P04629

(UniProtKB/Swiss-Prot/P) Details

High affinity nerve growth factor receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.897	Unknown: unspecified method	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.897	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.994	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.994	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Late endosome membrane (GO:0031902)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.897	Predicted: pTarget method	LOCATE	PubMed
Membrane	Dendrite (GO:0030425)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q59GJ0

Interaction Score

0.49

Q6NTA2

(UniProtKB/TrEmbl/P) Details

HNRNPL protein

Q59GJ0

Interaction Score

0.49

Q15274

(UniProtKB/Swiss-Prot/P) Details

Nicotinate-nucleotide pyrophosphorylase [carboxylating]

Q59GJ0

Interaction Score

0.21

O00303

(UniProtKB/Swiss-Prot/P) Details

Eukaryotic translation initiation factor 3 subunit F

Q59GJ0

Interaction Score

Q6IB98

(UniProtKB/TrEmbl/P) Details

Eukaryotic translation initiation factor 3 subunit H

Q59GJ0

Interaction Score

O95065

(UniProtKB/TrEmbl/P) Details

Eucaryotic translation initiation factor 4G isoform 1

Q59GJ0

Interaction Score

P78344

(UniProtKB/Swiss-Prot/P) Details

Eukaryotic translation initiation factor 4 gamma 2

Q59GJ0

Interaction Score

Q2TU89

(UniProtKB/TrEmbl/P) Details

Aging-associated protein 1

Q59GJ0

Interaction Score

X5DR71

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase receptor

Q59GJ0

Interaction Score

A4D210

(UniProtKB/TrEmbl/P) Details

Eukaryotic translation initiation factor 3 subunit B

Q59GJ0

Interaction Score

P51648

(UniProtKB/Swiss-Prot/P) Details

Fatty aldehyde dehydrogenase

Q59GJ0

Interaction Score

P52735

(UniProtKB/Swiss-Prot/P) Details

Guanine nucleotide exchange factor VAV2

Q59GJ0

Interaction Score

P21709

(UniProtKB/Swiss-Prot/P) Details

Ephrin type-A receptor 1

Q59GJ0

Interaction Score

D6RBW1

(UniProtKB/TrEmbl/P) Details

Eukaryotic translation initiation factor 4E

Q59GJ0

Interaction Score

Q8N7X8

(UniProtKB/Swiss-Prot/P) Details

SIGLEC family-like protein 1

Q59GJ0

Interaction Score

P06730

(UniProtKB/Swiss-Prot/P) Details

Eukaryotic translation initiation factor 4E

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	RNA-induced silencing complex (GO:0016442)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasmic stress granule (GO:0010494)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Chromatoid body (GO:0033391)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasmic mRNA processing body (GO:0000932)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Eukaryotic translation initiation factor 4F complex (GO:0016281)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	MRNA cap binding complex (GO:0005845)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q59GJ0

Interaction Score

Q9NYQ3

(UniProtKB/Swiss-Prot/P) Details

Hydroxyacid oxidase 2

Q59GJ0

Interaction Score

Q32Q75

(UniProtKB/TrEmbl/P) Details

Eukaryotic translation initiation factor 4E

Q59GJ0

Interaction Score

Q59ER8

(UniProtKB/TrEmbl/P) Details

Leucine-rich repeat-containing G protein-coupled receptor 4 variant

Q59GJ0

Interaction Score

O15372

(UniProtKB/Swiss-Prot/P) Details

Eukaryotic translation initiation factor 3 subunit H

Q59GJ0

Interaction Score

P54687

(UniProtKB/Swiss-Prot/P) Details

Branched-chain-amino-acid aminotransferase, cytosolic

Q59GJ0

Interaction Score

Q86VU5

(UniProtKB/Swiss-Prot/P) Details

Catechol O-methyltransferase domain-containing protein 1

Q59GJ0

Interaction Score

Q9BXB1

(UniProtKB/Swiss-Prot/P) Details

Leucine-rich repeat-containing G-protein coupled receptor 4

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Q59GJ0

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q59GJ0

P03372

Estrogen receptor

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q59GJ0

P49917

DNA ligase 4

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q59GJ0

Q13148

TAR DNA-binding protein 43

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q59GJ0

Q15428

Splicing factor 3A subunit 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q59GJ0

P14866

Heterogeneous nuclear ribonucleoprotein L

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q59GJ0

Q6PD62

RNA polymerase-associated protein CTR9 homolog

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q59GJ0

Q14694

Ubiquitin carboxyl-terminal hydrolase 10

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q59GJ0

P17980

26S proteasome regulatory subunit 6A

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q59GJ0

O43251

RNA binding protein fox-1 homolog 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q59GJ0

Q9NRC8

NAD-dependent protein deacetylase sirtuin-7

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q59GJ0

Q04637

Eukaryotic translation initiation factor 4 gamma 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q59GJ0

Q9BUB5

MAP kinase-interacting serine/threonine-protein kinase 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q59GJ0