Q94261

COP9/Signalosome and eIF3 complex-shared subunit 1    //   UniProt Profile 

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Species

C. elegans

Number of Interactions

15 / 18

Average Interaction Score

0.839

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.971 Experimental: experimental eSLDB PubMed 
Cytosol Eukaryotic 48S preinitiation complex (GO:0033290) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Eukaryotic 43S preinitiation complex (GO:0016282) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Eukaryotic translation initiation factor 3 complex (GO:0005852) 0.971 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Signalosome (GO:0008180) 0.958 Unknown: inferred from electronic annotation GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q94261

Interaction Score
0.998

P91001

(UniProtKB/Swiss-Prot/P) Details

COP9 signalosome complex subunit 5

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.992 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Signalosome (GO:0008180) 0.996 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol A band (GO:0031672) 0.992 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q94261

Interaction Score
0.997

Q9N359

(UniProtKB/Swiss-Prot/P) Details

COP9 signalosome complex subunit 4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.982 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.982 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Signalosome (GO:0008180) 0.982 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID, IntAct, CCSB, DIP

Interaction Source Publication:

PubMed , PubMed 

Q94261

Interaction Score
0.996

O01422

(UniProtKB/Swiss-Prot/P) Details

COP9 signalosome complex subunit 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.958 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Signalosome (GO:0008180) 0.982 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q94261

Interaction Score
0.996

Q9GS00

(UniProtKB/Swiss-Prot/P) Details

COP9 signalosome complex subunit 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.958 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Signalosome (GO:0008180) 0.982 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q94261

Interaction Score
0.977

O17754

(UniProtKB/Swiss-Prot/P) Details

Carboxypeptidase E

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.995 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Neuronal cell body (GO:0043025) 0.958 Experimental: inferred from direct assay GO PubMed 
Cytosol Perikaryon (GO:0043204) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.995 Predicted: inferred from biological aspect of ancestor GO PubMed 
Secretory-pathway Cytoplasmic vesicle (GO:0031410) 0.995 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Secretory granule (GO:0030141) 0.995 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Axon (GO:0030424) 0.94 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular space (GO:0005615) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Synaptic membrane (GO:0097060) 0.94 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID, DIP, IntAct, CCSB

Interaction Source Publication:

PubMed , PubMed 

Q94261

Interaction Score
0.96

Q17391

(UniProtKB/Swiss-Prot/P) Details

Cullin-3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cul3-RING ubiquitin ligase complex (GO:0031463) 0.86 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q94261

Interaction Score
0.883

Q965W3

(UniProtKB/TrEmbl/P) Details

Catechol-O-MethylTransferase family

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct, CCSB

Interaction Source Publication:

PubMed 

Q94261

Interaction Score
0.883

P43509

(UniProtKB/Swiss-Prot/P) Details

Cathepsin B-like cysteine proteinase 5

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Lysosome (GO:0005764) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Lysosome (GO:0005764) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

DIP, IntAct, BioGRID, CCSB

Interaction Source Publication:

PubMed , PubMed 

Q94261

Interaction Score
0.883

P42170

(UniProtKB/Swiss-Prot/P) Details

Ribonucleoside-diphosphate reductase small chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Ribonucleoside-diphosphate reductase complex (GO:0005971) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

DIP, IntAct, CCSB, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q94261

Interaction Score
0.872

Q9XWK3

(UniProtKB/TrEmbl/P) Details

Nuclear Pore complex Protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nuclear pore central transport channel (GO:0044613) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID, IntAct, CCSB, DIP

Interaction Source Publication:

PubMed , PubMed 

Q94261

Interaction Score
0.828

Q18967

(UniProtKB/Swiss-Prot/P) Details

Eukaryotic translation initiation factor 3 subunit F

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.853 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Eukaryotic 48S preinitiation complex (GO:0033290) 0.853 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Eukaryotic 43S preinitiation complex (GO:0016282) 0.853 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q94261

Interaction Score
0.679

Q9GRZ9

(UniProtKB/TrEmbl/P) Details

Transmembrane and Coiled-Coil protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.8 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct, CCSB, DIP

Interaction Source Publication:

PubMed , PubMed 

Q94261

Interaction Score
0.671

Q20676

(UniProtKB/TrEmbl/P) Details

Propionyl Coenzyme A Carboxylase Beta subunit

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

DIP, BioGRID, IntAct, CCSB

Interaction Source Publication:

PubMed , PubMed 

Q94261

Interaction Score
0.671

Q8WQF1

(UniProtKB/TrEmbl/P) Details

Propionyl Coenzyme A Carboxylase Beta subunit

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID, CCSB

Interaction Source Publication:

PubMed , PubMed 

Q94261

Interaction Score
0.291

Q19202

(UniProtKB/Swiss-Prot/P) Details

Apyrase apy-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Endomembrane system (GO:0012505) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Membrane Membrane (GO:0016020) 0.958 Experimental: inferred from mutant phenotype GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, DIP, IntAct

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015