Q969G2

LIM/homeobox protein Lhx4 // UniProt Profile

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Species	H. sapiens
Number of Interactions	76 / 88
Average Interaction Score	0.675

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q969G2

Interaction Score

0.996

Q13485

(UniProtKB/Swiss-Prot/P) Details

Mothers against decapentaplegic homolog 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	SMAD protein complex (GO:0071141)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcription factor complex (GO:0005667)	1	Predicted: inferred from physical interaction	GO	PubMed
Nucleus	Activin responsive factor complex (GO:0032444)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q969G2

Interaction Score

0.996

Q9Y5N6

(UniProtKB/Swiss-Prot/P) Details

Origin recognition complex subunit 6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Origin recognition complex (GO:0000808)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear origin of replication recognition complex (GO:0005664)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

CCSB, BioGRID, IntAct

Interaction Source Publication:

PubMed

Q969G2

Interaction Score

0.996

O43679

(UniProtKB/Swiss-Prot/P) Details

LIM domain-binding protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell leading edge (GO:0031252)	0.988	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcription factor complex (GO:0005667)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.988	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID, DIP, IntAct

Interaction Source Publication:

PubMed

Q969G2

Interaction Score

0.996

Q9C086

(UniProtKB/Swiss-Prot/P) Details

INO80 complex subunit B

Q969G2

Interaction Score

0.996

P25490

(UniProtKB/Swiss-Prot/P) Details

Transcriptional repressor protein YY1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear matrix (GO:0016363)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcription factor complex (GO:0005667)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	PcG protein complex (GO:0031519)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Ino80 complex (GO:0031011)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q969G2

Interaction Score

0.996

Q86U70

(UniProtKB/Swiss-Prot/P) Details

LIM domain-binding protein 1

Q969G2

Interaction Score

0.996

P57086

(UniProtKB/Swiss-Prot/P) Details

SCAN domain-containing protein 1

Q969G2

Interaction Score

0.996

P81877

(UniProtKB/Swiss-Prot/P) Details

Single-stranded DNA-binding protein 2

Q969G2

Interaction Score

0.996

Q9HD42

(UniProtKB/Swiss-Prot/P) Details

Charged multivesicular body protein 1a

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Endomembrane system (GO:0012505)	0.998	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear matrix (GO:0016363)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.86	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	ESCRT III complex (GO:0000815)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Condensed nuclear chromosome (GO:0000794)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.998	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q969G2

Interaction Score

0.996

P09012

(UniProtKB/Swiss-Prot/P) Details

U1 small nuclear ribonucleoprotein A

Q969G2

Interaction Score

0.996

P61371

(UniProtKB/Swiss-Prot/P) Details

Insulin gene enhancer protein ISL-1

Q969G2

Interaction Score

0.996

Q16384

(UniProtKB/Swiss-Prot/P) Details

Protein SSX1

Q969G2

Interaction Score

0.995

Q9BV90

(UniProtKB/Swiss-Prot/P) Details

U11/U12 small nuclear ribonucleoprotein 25 kDa protein

Q969G2

Interaction Score

0.995

P36404

(UniProtKB/Swiss-Prot/P) Details

ADP-ribosylation factor-like protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	0.86	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrial intermembrane space (GO:0005758)	0.86	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.996	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.996	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cilium (GO:0005929)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Lateral plasma membrane (GO:0016328)	0.998	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q969G2

Interaction Score

0.994

Q68CP9

(UniProtKB/Swiss-Prot/P) Details

AT-rich interactive domain-containing protein 2

Q969G2

Interaction Score

0.994

O15169

(UniProtKB/Swiss-Prot/P) Details

Axin-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Beta-catenin destruction complex (GO:0030877)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleolus (GO:0005730)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Cell periphery (GO:0071944)	0.992	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: experimental	Organelle	PubMed
Membrane	Lateral plasma membrane (GO:0016328)	0.992	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q969G2

Interaction Score

0.994

Q00444

(UniProtKB/Swiss-Prot/P) Details

Homeobox protein Hox-C5

Q969G2

Interaction Score

0.993

Q8N6N3

(UniProtKB/Swiss-Prot/P) Details

UPF0690 protein C1orf52

Q969G2

Interaction Score

0.993

Q2TAL8

(UniProtKB/Swiss-Prot/P) Details

Glutamine-rich protein 1

Q969G2

Interaction Score

0.992

Q5QP82

(UniProtKB/Swiss-Prot/P) Details

DDB1- and CUL4-associated factor 10

Q969G2

Interaction Score

0.992

P28069

(UniProtKB/Swiss-Prot/P) Details

Pituitary-specific positive transcription factor 1

Q969G2

Interaction Score

0.991

O43422

(UniProtKB/Swiss-Prot/P) Details

52 kDa repressor of the inhibitor of the protein kinase

Q969G2

Interaction Score

0.991

Q9Y3Q8

(UniProtKB/Swiss-Prot/P) Details

TSC22 domain family protein 4

Q969G2

Interaction Score

0.99

Q8N2Z9

(UniProtKB/Swiss-Prot/P) Details

Centromere protein S

Q969G2

Interaction Score

0.988

Q8N680

(UniProtKB/Swiss-Prot/P) Details

Zinc finger and BTB domain-containing protein 2

Q969G2

Interaction Score

0.984

Q6ZN55

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 574

Q969G2

Interaction Score

0.984

Q96A47

(UniProtKB/Swiss-Prot/P) Details

Insulin gene enhancer protein ISL-2

Q969G2

Interaction Score

0.984

P36508

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 76

Q969G2

Interaction Score

0.983

Q7Z6J9

(UniProtKB/Swiss-Prot/P) Details

tRNA-splicing endonuclease subunit Sen54

Q969G2

Interaction Score

0.969

Q9BWG4

(UniProtKB/Swiss-Prot/P) Details

Single-stranded DNA-binding protein 4

Q969G2

Interaction Score

0.956

E9PFI4

(UniProtKB/TrEmbl/P) Details

LIM domain-binding protein 2

Q969G2

Interaction Score

0.956

G5E9Y7

(UniProtKB/TrEmbl/P) Details

LIM domain binding 2, isoform CRA_b

Q969G2

Interaction Score

0.954

Q9NP98

(UniProtKB/Swiss-Prot/P) Details

Myozenin-1

Q969G2

Interaction Score

0.936

Q8IW35

(UniProtKB/Swiss-Prot/P) Details

Centrosomal protein of 97 kDa

Q969G2

Interaction Score

0.936

A0A0C4DFM2

(UniProtKB/TrEmbl/P) Details

HCG1643764, isoform CRA_b

Q969G2

Interaction Score

0.936

Q9NYB9

(UniProtKB/Swiss-Prot/P) Details

Abl interactor 2

Q969G2

Interaction Score

0.933

O75604

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase 2

Q969G2

Interaction Score

0.907

Q71MF7

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein FP972

Q969G2

Interaction Score

0.797

Q9Y6H1

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

Q969G2

Interaction Score

0.797

A0A087X159

(UniProtKB/TrEmbl/P) Details

Single-stranded DNA-binding protein 2

Q969G2

Interaction Score

0.797

A0A0C4DG21

(UniProtKB/TrEmbl/P) Details

Abl interactor 2

Q969G2

Interaction Score

0.797

B7Z836

(UniProtKB/TrEmbl/P) Details

cDNA FLJ51162, highly similar to Abl interactor 2

Q969G2

Interaction Score

0.797

E9PEZ7

(UniProtKB/TrEmbl/P) Details

Abl interactor 2

Q969G2

Interaction Score

0.797

F8WAL6

(UniProtKB/TrEmbl/P) Details

Abl interactor 2

Q969G2

Interaction Score

0.797

Q9Y6W5

(UniProtKB/Swiss-Prot/P) Details

Wiskott-Aldrich syndrome protein family member 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	SCAR complex (GO:0031209)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Ruffle (GO:0001726)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	0.997	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	0.997	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell-cell junction (GO:0005911)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Synapse (GO:0045202)	0.997	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q969G2

Interaction Score

0.797

Q96LJ7

(UniProtKB/Swiss-Prot/P) Details

Dehydrogenase/reductase SDR family member 1

Q969G2

Interaction Score

0.797

Q9BR76

(UniProtKB/Swiss-Prot/P) Details

Coronin-1B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell leading edge (GO:0031252)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Actin filament (GO:0005884)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Stress fiber (GO:0001725)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell periphery (GO:0071944)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q969G2

Interaction Score

0.797

Q7Z4G4

(UniProtKB/Swiss-Prot/P) Details

tRNA (guanine(10)-N2)-methyltransferase homolog

Q969G2

Interaction Score

0.797

Q5T7W7

(UniProtKB/Swiss-Prot/P) Details

Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2

Q969G2

Interaction Score

0.787

Q8IZP0

(UniProtKB/Swiss-Prot/P) Details

Abl interactor 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	SCAR complex (GO:0031209)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.86	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.86	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Growth cone (GO:0030426)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Filopodium tip (GO:0032433)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q969G2

Interaction Score

0.787

Q96JK2

(UniProtKB/Swiss-Prot/P) Details

DDB1- and CUL4-associated factor 5

Q969G2

Interaction Score

0.697

Q17RB8

(UniProtKB/Swiss-Prot/P) Details

LON peptidase N-terminal domain and RING finger protein 1

Q969G2

Interaction Score

0.697

Q8TBB7

(UniProtKB/TrEmbl/P) Details

DDB1- and CUL4-associated factor 5

Q969G2

Interaction Score

0.697

Q9Y3C0

(UniProtKB/Swiss-Prot/P) Details

WASH complex subunit 3

Q969G2

Interaction Score

0.697

Q00526

(UniProtKB/Swiss-Prot/P) Details

Cyclin-dependent kinase 3

Q969G2

Interaction Score

0.299

Q96F07

(UniProtKB/Swiss-Prot/P) Details

Cytoplasmic FMR1-interacting protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Neuron projection (GO:0043005)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.986	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.986	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Synapse (GO:0045202)	0.986	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q969G2

Interaction Score

0.299

Q8IYS8

(UniProtKB/Swiss-Prot/P) Details

Biorientation of chromosomes in cell division protein 1-like 2

Q969G2

Interaction Score

0.299

Q2WGJ6

(UniProtKB/Swiss-Prot/P) Details

Kelch-like protein 38

Q969G2

Interaction Score

A0A0C4DGE8

(UniProtKB/TrEmbl/P) Details

LON peptidase N-terminal domain and RING finger protein 1

Q969G2

Interaction Score

Q9UG01

(UniProtKB/Swiss-Prot/P) Details

Intraflagellar transport protein 172 homolog

Q969G2

Interaction Score

O60880

(UniProtKB/Swiss-Prot/P) Details

SH2 domain-containing protein 1A

Q969G2

Interaction Score

Q8NBS9

(UniProtKB/Swiss-Prot/P) Details

Thioredoxin domain-containing protein 5

Q969G2

Interaction Score

Q6P4F2

(UniProtKB/Swiss-Prot/P) Details

Ferredoxin-2, mitochondrial

Q969G2

Interaction Score

E9PG22

(UniProtKB/TrEmbl/P) Details

Centrosomal protein of 97 kDa

Q969G2

Interaction Score

E7EVJ5

(UniProtKB/TrEmbl/P) Details

Cytoplasmic FMR1-interacting protein

Q969G2

Interaction Score

Q7L576

(UniProtKB/Swiss-Prot/P) Details

Cytoplasmic FMR1-interacting protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	SCAR complex (GO:0031209)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	MRNA cap binding complex (GO:0005845)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Dendritic growth cone (GO:0044294)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Ruffle (GO:0001726)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Filopodium tip (GO:0032433)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuron projection (GO:0043005)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axonal growth cone (GO:0044295)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Unknown: HDA	GO	PubMed
Membrane	Excitatory synapse (GO:0060076)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Terminal button (GO:0043195)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q969G2

Interaction Score

A0A0A0MRT6

(UniProtKB/TrEmbl/P) Details

Abl interactor 1

Q969G2

Interaction Score

B6VEX4

(UniProtKB/TrEmbl/P) Details

Abl interactor 1

Q969G2

Interaction Score

A2TDC0

(UniProtKB/TrEmbl/P) Details

Titin-cap (Telethonin), isoform CRA_a

Q969G2

Interaction Score

O15273

(UniProtKB/Swiss-Prot/P) Details

Telethonin

Q969G2

Interaction Score

Q12798

(UniProtKB/Swiss-Prot/P) Details

Centrin-1

Q969G2

Interaction Score

Q86UY0

(UniProtKB/TrEmbl/P) Details

TXNDC5 protein

Q969G2

Interaction Score

Q9UPY8

(UniProtKB/Swiss-Prot/P) Details

Microtubule-associated protein RP/EB family member 3

Q969G2

Interaction Score

O75865

(UniProtKB/Swiss-Prot/P) Details

Trafficking protein particle complex subunit 6A

Q969G2

Interaction Score

Q96HE7

(UniProtKB/Swiss-Prot/P) Details

ERO1-like protein alpha

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.3	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	0.999	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.902	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	0.902	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q969G2

Interaction Score

P59910

(UniProtKB/Swiss-Prot/P) Details

DnaJ homolog subfamily B member 13

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Q969G2

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q969G2

Q13485

Mothers against decapentaplegic homolog 4

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969G2

Q9Y5N6

Origin recognition complex subunit 6

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969G2

O43679

LIM domain-binding protein 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969G2

Q9C086

INO80 complex subunit B

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969G2

P25490

Transcriptional repressor protein YY1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969G2

Q86U70

LIM domain-binding protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969G2

P57086

SCAN domain-containing protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969G2

P81877

Single-stranded DNA-binding protein 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969G2

Q9HD42

Charged multivesicular body protein 1a

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969G2

P09012

U1 small nuclear ribonucleoprotein A

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969G2

P61371

Insulin gene enhancer protein ISL-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969G2

Q16384

Protein SSX1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q969G2