Q96DZ1

Endoplasmic reticulum lectin 1 // UniProt Profile

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Species	H. sapiens
Number of Interactions	45 / 63
Average Interaction Score	0.744

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.992	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.992	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	0.992	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum quality control compartment (GO:0044322)	0.992	Unknown: traceable author statement	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q96DZ1

Interaction Score

0.997

P11021

(UniProtKB/Swiss-Prot/P) Details

Endoplasmic reticulum chaperone BiP

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.966	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell surface (GO:0009986)	0.966	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Myelin sheath (GO:0043209)	0.966	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Endomembrane system (GO:0012505)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from mutant phenotype	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	Organelle	PubMed
Nucleus	Signalosome (GO:0008180)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Smooth endoplasmic reticulum (GO:0005790)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum chaperone complex (GO:0034663)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment (GO:0005793)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Melanosome (GO:0042470)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.96	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.966	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.966	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.966	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96DZ1

Interaction Score

0.997

P14625

(UniProtKB/Swiss-Prot/P) Details

Endoplasmin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.986	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Endomembrane system (GO:0012505)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Unknown: HDA	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.86	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum chaperone complex (GO:0034663)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endocytic vesicle lumen (GO:0071682)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Melanosome (GO:0042470)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.98	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.98	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.98	Unknown: HDA	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.98	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.986	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.986	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.986	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96DZ1

Interaction Score

0.997

P18850

(UniProtKB/Swiss-Prot/P) Details

Cyclic AMP-dependent transcription factor ATF-6 alpha

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.994	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.994	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear envelope (GO:0005635)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	1	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.96	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96DZ1

Interaction Score

0.997

P01009

(UniProtKB/Swiss-Prot/P) Details

Alpha-1-antitrypsin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.994	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	0.999	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment membrane (GO:0033116)	0.999	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Platelet alpha granule lumen (GO:0031093)	0.999	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	ER to Golgi transport vesicle (GO:0030134)	0.999	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.992	Unknown: non-traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.992	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.992	Experimental: inferred from mutant phenotype	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.992	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.994	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96DZ1

Interaction Score

0.997

P14314

(UniProtKB/Swiss-Prot/P) Details

Glucosidase 2 subunit beta

Q96DZ1

Interaction Score

0.996

Q9GZP9

(UniProtKB/Swiss-Prot/P) Details

Derlin-2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Signal recognition particle (GO:0048500)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Signal recognition particle receptor complex (GO:0005785)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum quality control compartment (GO:0044322)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.86	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96DZ1

Interaction Score

0.996

Q86TM6

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase synoviolin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.7	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Smooth endoplasmic reticulum (GO:0005790)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Hrd1p ubiquitin ligase complex (GO:0000836)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Hrd1p ubiquitin ligase ERAD-L complex (GO:0000839)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	1	Unknown: non-traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum quality control compartment (GO:0044322)	1	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.992	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: experimental	Human Proteinpedia	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96DZ1

Interaction Score

0.996

Q13438

(UniProtKB/Swiss-Prot/P) Details

Protein OS-9

Q96DZ1

Interaction Score

0.995

Q9BZQ6

(UniProtKB/Swiss-Prot/P) Details

ER degradation-enhancing alpha-mannosidase-like protein 3

Q96DZ1

Interaction Score

0.991

Q99941

(UniProtKB/Swiss-Prot/P) Details

Cyclic AMP-dependent transcription factor ATF-6 beta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	RNA polymerase II transcription factor complex (GO:0090575)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Protein-DNA complex (GO:0032993)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.98	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.98	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	0.98	Unknown: non-traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.98	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.8	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96DZ1

Interaction Score

0.99

Q5K4L6

(UniProtKB/Swiss-Prot/P) Details

Long-chain fatty acid transport protein 3

Q96DZ1

Interaction Score

0.987

Q969N2

(UniProtKB/Swiss-Prot/P) Details

GPI transamidase component PIG-T

Q96DZ1

Interaction Score

0.986

O75503

(UniProtKB/Swiss-Prot/P) Details

Ceroid-lipofuscinosis neuronal protein 5

Q96DZ1

Interaction Score

0.979

P07307

(UniProtKB/Swiss-Prot/P) Details

Asialoglycoprotein receptor 2

Q96DZ1

Interaction Score

0.978

Q9UBV2

(UniProtKB/Swiss-Prot/P) Details

Protein sel-1 homolog 1

Q96DZ1

Interaction Score

0.974

Q9Y385

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-conjugating enzyme E2 J1

Q96DZ1

Interaction Score

0.974

Q8IWF2

(UniProtKB/Swiss-Prot/P) Details

FAD-dependent oxidoreductase domain-containing protein 2

Q96DZ1

Interaction Score

0.97

Q9H3G5

(UniProtKB/Swiss-Prot/P) Details

Probable serine carboxypeptidase CPVL

Q96DZ1

Interaction Score

0.952

P19438

(UniProtKB/Swiss-Prot/P) Details

Tumor necrosis factor receptor superfamily member 1A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.96	Experimental: experimental	eSLDB	PubMed
Membrane	Cell surface (GO:0009986)	1	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.96	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.992	Unknown: non-traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.992	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.992	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane raft (GO:0045121)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q96DZ1

Interaction Score

0.932

O95390

(UniProtKB/Swiss-Prot/P) Details

Growth/differentiation factor 11

Q96DZ1

Interaction Score

0.925

P60604

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-conjugating enzyme E2 G2

Q96DZ1

Interaction Score

0.909

Q6AZW6

(UniProtKB/TrEmbl/P) Details

Activating transcription factor 6 beta

Q96DZ1

Interaction Score

0.863

Q29983

(UniProtKB/Swiss-Prot/P) Details

MHC class I polypeptide-related sequence A

Q96DZ1

Interaction Score

0.853

P01241

(UniProtKB/Swiss-Prot/P) Details

Somatotropin

Q96DZ1

Interaction Score

0.837

Q9NT22

(UniProtKB/Swiss-Prot/P) Details

EMILIN-3

Q96DZ1

Interaction Score

0.801

Q13488

(UniProtKB/Swiss-Prot/P) Details

V-type proton ATPase 116 kDa subunit a isoform 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.51	Unknown: traceable author statement	GO	PubMed
Cytosol	Vacuolar proton-transporting V-type ATPase complex (GO:0016471)	0.853	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Vacuolar proton-transporting V-type ATPase, V0 domain (GO:0000220)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	0.853	Unknown: HDA	GO	PubMed
Secretory-pathway	Phagocytic vesicle membrane (GO:0030670)	0.51	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.998	Unknown: traceable author statement	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	0.998	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96DZ1

Interaction Score

0.793

X6R3N0

(UniProtKB/TrEmbl/P) Details

Long-chain fatty acid transport protein 3

Q96DZ1

Interaction Score

0.793

I3L3R8

(UniProtKB/TrEmbl/P) Details

Derlin-2

Q96DZ1

Interaction Score

0.793

Q9UBU6

(UniProtKB/Swiss-Prot/P) Details

Protein FAM8A1

Q96DZ1

Interaction Score

0.793

K7ELL7

(UniProtKB/TrEmbl/P) Details

Glucosidase 2 subunit beta

Q96DZ1

Interaction Score

0.788

Q9NRD1

(UniProtKB/Swiss-Prot/P) Details

F-box only protein 6

Q96DZ1

Interaction Score

0.699

Q15831

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase STK11

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	TCR signalosome (GO:0036398)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed

Q96DZ1

Interaction Score

0.694

Q96QC4

(UniProtKB/TrEmbl/P) Details

MHC class I polypeptide-related sequence A, isoform CRA_c

Q96DZ1

Interaction Score

0.694

Q86TS9

(UniProtKB/Swiss-Prot/P) Details

39S ribosomal protein L52, mitochondrial

Q96DZ1

Interaction Score

0.679

Q9UKA2

(UniProtKB/Swiss-Prot/P) Details

F-box/LRR-repeat protein 4

Q96DZ1

Interaction Score

0.631

Q2MV58

(UniProtKB/Swiss-Prot/P) Details

Tectonic-1

Q96DZ1

Interaction Score

0.56

B4DIB9

(UniProtKB/TrEmbl/P) Details

cDNA FLJ55161, highly similar to Tectonic-1

Q96DZ1

Interaction Score

0.49

Q96A35

(UniProtKB/Swiss-Prot/P) Details

39S ribosomal protein L24, mitochondrial

Q96DZ1

Interaction Score

0.21

Q16827

(UniProtKB/Swiss-Prot/P) Details

Receptor-type tyrosine-protein phosphatase O

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Growth cone (GO:0030426)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Neuron projection (GO:0043005)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Axon (GO:0030424)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Lateral plasma membrane (GO:0016328)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q96DZ1

Interaction Score

Q3ZCU6

(UniProtKB/TrEmbl/P) Details

SEL1L protein

Q96DZ1

Interaction Score

A0A024R931

(UniProtKB/TrEmbl/P) Details

alpha-1,2-Mannosidase

Q96DZ1

Interaction Score

G5E9P5

(UniProtKB/TrEmbl/P) Details

39S ribosomal protein L52, mitochondrial

Q96DZ1

Interaction Score

Q7Z4G9

(UniProtKB/TrEmbl/P) Details

HBxAg-binding protein

Q96DZ1

Interaction Score

A0A024R5E5

(UniProtKB/TrEmbl/P) Details

V-type proton ATPase subunit a

Q96DZ1

Interaction Score

Q9BZ76

(UniProtKB/Swiss-Prot/P) Details

Contactin-associated protein-like 3

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Q96DZ1

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q96DZ1

P11021

Endoplasmic reticulum chaperone BiP

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DZ1

P14625

Endoplasmin

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DZ1

P18850

Cyclic AMP-dependent transcription factor ATF-6 alpha

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DZ1

P01009

Alpha-1-antitrypsin

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DZ1

P14314

Glucosidase 2 subunit beta

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DZ1

Q9GZP9

Derlin-2

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DZ1

Q86TM6

E3 ubiquitin-protein ligase synoviolin

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DZ1

Q13438

Protein OS-9

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DZ1

Q9BZQ6

ER degradation-enhancing alpha-mannosidase-like protein 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DZ1

Q99941

Cyclic AMP-dependent transcription factor ATF-6 beta

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DZ1

Q5K4L6

Long-chain fatty acid transport protein 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DZ1

Q969N2

GPI transamidase component PIG-T

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q96DZ1