Q9GYJ9

Sorting NeXin    //   UniProt Profile 

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Species

C. elegans

Number of Interactions

25 / 35

Average Interaction Score

0.788

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.86 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Early endosome (GO:0005769) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.999 Predicted: inferred from biological aspect of ancestor GO PubMed 
Secretory-pathway Phagocytic vesicle (GO:0045335) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Early phagosome (GO:0032009) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Extrinsic to membrane (GO:0019898) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q9GYJ9

Interaction Score
1

P91857

(UniProtKB/TrEmbl/P) Details

RAB family

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cell cortex (GO:0005938) 0.94 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endosome (GO:0005768) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Early endosome (GO:0005769) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Early endosome membrane (GO:0031901) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Phagocytic vesicle (GO:0045335) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Periciliary membrane compartment (GO:1990075) 0.94 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q9GYJ9

Interaction Score
1

Q93561

(UniProtKB/Swiss-Prot/P) Details

Derlin-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Signal recognition particle (GO:0048500) 0.988 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Perinuclear endoplasmic reticulum (GO:0097038) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular organelle (GO:0043229) 0.988 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Signal recognition particle receptor complex (GO:0005785) 0.999 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Endosome (GO:0005768) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Early endosome (GO:0005769) 0.999 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

CCSB, IntAct, DIP, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q9GYJ9

Interaction Score
0.998

G5ED36

(UniProtKB/TrEmbl/P) Details

Endocytosis protein RME-8

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Recycling endosome (GO:0055037) 0.998 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Early endosome (GO:0005769) 0.998 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Late endosome (GO:0005770) 0.998 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.998 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

Q9GYJ9

Interaction Score
0.994

D9PTP5

(UniProtKB/TrEmbl/P) Details

Sorting NeXin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endosome (GO:0005768) 0.988 Predicted: inferred from biological aspect of ancestor GO PubMed 
Secretory-pathway Phagocytic vesicle (GO:0045335) 0.988 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Early phagosome (GO:0032009) 0.988 Experimental: inferred from direct assay GO PubMed 
Membrane Extrinsic to membrane (GO:0019898) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q9GYJ9

Interaction Score
0.981

Q21053

(UniProtKB/TrEmbl/P) Details

Vacuolar protein sorting-associated protein 35

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Retromer complex (GO:0030904) 0.997 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Retromer complex, inner shell (GO:0030906) 0.997 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Neuronal cell body (GO:0043025) 0.997 Experimental: inferred from mutant phenotype GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.997 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.997 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.997 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Late endosome (GO:0005770) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Dendrite (GO:0030425) 0.8 Experimental: inferred from mutant phenotype GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9GYJ9

Interaction Score
0.97

O01258

(UniProtKB/Swiss-Prot/P) Details

Vacuolar protein sorting-associated protein 26

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Retromer complex (GO:0030904) 0.937 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.937 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.937 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endosome (GO:0005768) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9GYJ9

Interaction Score
0.953

Q86D99

(UniProtKB/TrEmbl/P) Details

Vacuolar protein sorting-associated protein 29

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Retromer complex (GO:0030904) 0.981 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.981 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.981 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.981 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endosome (GO:0005768) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9GYJ9

Interaction Score
0.94

Q9XWD6

(UniProtKB/Swiss-Prot/P) Details

Cell death abnormality protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Phagocytic vesicle membrane (GO:0030670) 0.8 Experimental: inferred from direct assay GO PubMed 
Membrane Pseudopodium membrane (GO:0031260) 1 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Phagocytic cup (GO:0001891) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9GYJ9

Interaction Score
0.906

G5EDI2

(UniProtKB/TrEmbl/P) Details

Reticulon-like protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Endomembrane system (GO:0012505) 0.8 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Integral to endoplasmic reticulum membrane (GO:0030176) 0.7 Predicted: inferred from sequence or structural similarity GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9GYJ9

Interaction Score
0.857

Q18503

(UniProtKB/TrEmbl/P) Details

Major sperm protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct, DIP, BioGRID

Interaction Source Publication:

PubMed 

Q9GYJ9

Interaction Score
0.847

Q7JLB1

(UniProtKB/TrEmbl/P) Details

Reticulon-like protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

CCSB, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q9GYJ9

Interaction Score
0.847

Q23187

(UniProtKB/TrEmbl/P) Details

Reticulon-like protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

CCSB, DIP, BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

Q9GYJ9

Interaction Score
0.847

Q7JLB0

(UniProtKB/TrEmbl/P) Details

Reticulon-like protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID, CCSB

Interaction Source Publication:

PubMed , PubMed 

Q9GYJ9

Interaction Score
0.824

Q23237

(UniProtKB/Swiss-Prot/P) Details

Proteasome subunit beta type-3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.958 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Proteasome core complex, beta-subunit complex (GO:0019774) 0.958 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID, CCSB, IntAct

Interaction Source Publication:

PubMed , PubMed , PubMed 

Q9GYJ9

Interaction Score
0.783

Q21648

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct, BioGRID, DIP

Interaction Source Publication:

PubMed 

Q9GYJ9

Interaction Score
0.783

Q9XVX5

(UniProtKB/TrEmbl/P) Details

Vacuolar protein sorting-associated protein 29

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9GYJ9

Interaction Score
0.699

Q23188

(UniProtKB/TrEmbl/P) Details

Reticulon-like protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID, CCSB

Interaction Source Publication:

PubMed , PubMed 

Q9GYJ9

Interaction Score
0.637

O02268

(UniProtKB/TrEmbl/P) Details

Dietary Restriction Response

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Integral to membrane (GO:0016021) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

DIP, CCSB, IntAct, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q9GYJ9

Interaction Score
0.602

Q18964

(UniProtKB/Swiss-Prot/P) Details

WD repeat and FYVE domain-containing protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct, DIP, BioGRID, CCSB

Interaction Source Publication:

PubMed , PubMed 

Q9GYJ9

Interaction Score
0.602

Q9U1S5

(UniProtKB/TrEmbl/P) Details

BZIP transcription factor family

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID, IntAct, DIP

Interaction Source Publication:

PubMed 

Q9GYJ9

Interaction Score
0.553

Q18089

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Integral to membrane (GO:0016021) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct, DIP, BioGRID

Interaction Source Publication:

PubMed 

Q9GYJ9

Interaction Score
0.553

Q9N431

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Integral to membrane (GO:0016021) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

CCSB, IntAct, DIP, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q9GYJ9

Interaction Score
0.553

O61521

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Integral to membrane (GO:0016021) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct, CCSB, DIP, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q9GYJ9

Interaction Score
0.49

P34296

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized protein C06E1.1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

CCSB, IntAct

Interaction Source Publication:

PubMed 

Q9GYJ9

Interaction Score
0.49

O62178

(UniProtKB/TrEmbl/P) Details

Receptor Mediated Endocytosis

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015