Q9Y520

Protein PRRC2C // UniProt Profile

Custom Settings: Use these controls to filter the data displayed on this page. The parameters apply to both the query protein and its interactors. Details

The (filtered) results are available for download, see the help for details. Download The Results

Species	H. sapiens
Number of Interactions	66 / 84
Average Interaction Score	0.845

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

First-Neighbour Network Visualization

Toggle Display

The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

Q9Y520

Interaction Score

P11142

(UniProtKB/Swiss-Prot/P) Details

Heat shock cognate 71 kDa protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Prp19 complex (GO:0000974)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Ubiquitin ligase complex (GO:0000151)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular (GO:0005622)	1	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Spliceosomal complex (GO:0005681)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosomal lumen (GO:0043202)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Melanosome (GO:0042470)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.657	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Clathrin sculpted gamma-aminobutyric acid transport vesicle membrane (GO:0061202)	0.657	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.986	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.986	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.986	Unknown: HDA	GO	PubMed
Extracellular	Blood microparticle (GO:0072562)	0.986	Unknown: HDA	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.986	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.931	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.931	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.931	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.931	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.999

Q13283

(UniProtKB/Swiss-Prot/P) Details

Ras GTPase-activating protein-binding protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Perikaryon (GO:0043204)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasmic stress granule (GO:0010494)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	eSLDB	PubMed
Cytosol	Vesicle (GO:0031982)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Focal adhesion (GO:0005925)	0.86	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.999

Q15717

(UniProtKB/Swiss-Prot/P) Details

ELAV-like protein 1

Q9Y520

Interaction Score

0.999

Q9H0R8

(UniProtKB/Swiss-Prot/P) Details

Gamma-aminobutyric acid receptor-associated protein-like 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cell body (GO:0044297)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular (GO:0005622)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: inferred from genetic interaction	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.897	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Autophagic vacuole (GO:0005776)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Autophagic vacuole membrane (GO:0000421)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite cytoplasm (GO:0032839)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite membrane (GO:0032590)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.999

P27635

(UniProtKB/Swiss-Prot/P) Details

60S ribosomal protein L10

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytosolic large ribosomal subunit (GO:0022625)	0.999	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.988	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Smooth endoplasmic reticulum (GO:0005790)	0.998	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.999

Q9NQC7

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase CYLD

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Spindle (GO:0005819)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cilium basal body (GO:0036064)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasmic microtubule (GO:0005881)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Extrinsic to internal side of plasma membrane (GO:0031234)	0.96	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.999

O60260

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase parkin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ubiquitin ligase complex (GO:0000151)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	LUBAC complex (GO:0071797)	1	Predicted: inferred from physical interaction	GO	PubMed
Cytosol	SCF ubiquitin ligase complex (GO:0019005)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Aggresome (GO:0016235)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: inferred from mutant phenotype	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.8	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.7	Predicted: pTarget method	LOCATE	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.999

P49841

(UniProtKB/Swiss-Prot/P) Details

Glycogen synthase kinase-3 beta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.994	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.994	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Beta-catenin destruction complex (GO:0030877)	0.994	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.994	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Unknown: traceable author statement	GO	PubMed
Cytosol	Centrosome (GO:0005813)	0.994	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.982	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Axon (GO:0030424)	0.982	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.982	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.998

P19320

(UniProtKB/Swiss-Prot/P) Details

Vascular cell adhesion protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Apical part of cell (GO:0045177)	0.972	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Podosome (GO:0002102)	0.972	Experimental: inferred from direct assay	GO	PubMed
Membrane	Microvillus (GO:0005902)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Filopodium (GO:0030175)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.988	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.988	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Sarcolemma (GO:0042383)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	External side of plasma membrane (GO:0009897)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex (GO:0071065)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.972	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.998

P13569

(UniProtKB/Swiss-Prot/P) Details

Cystic fibrosis transmembrane conductance regulator

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.972	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.94	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum Sec complex (GO:0031205)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi-associated vesicle membrane (GO:0030660)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Recycling endosome (GO:0055037)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Recycling endosome membrane (GO:0055038)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	0.972	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Clathrin coated vesicle membrane (GO:0030665)	1	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Chloride channel complex (GO:0034707)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.997

Q96GD4

(UniProtKB/Swiss-Prot/P) Details

Aurora kinase B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Midbody (GO:0030496)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Spindle (GO:0005819)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Spindle midzone (GO:0051233)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Mitotic spindle midzone (GO:1990023)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Spindle microtubule (GO:0005876)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Spindle pole centrosome (GO:0031616)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Chromosome passenger complex (GO:0032133)	1	Predicted: inferred from physical interaction	GO	PubMed
Nucleus	Condensed nuclear chromosome, centromeric region (GO:0000780)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromocenter (GO:0010369)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Condensed chromosome, centromeric region (GO:0000779)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Kinetochore (GO:0000776)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.997

O14965

(UniProtKB/Swiss-Prot/P) Details

Aurora kinase A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.657	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Pronucleus (GO:0045120)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Female germ germinal vesicle (GO:0042585)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle (GO:0005819)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Meiotic spindle (GO:0072687)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Spindle midzone (GO:0051233)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Spindle microtubule (GO:0005876)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Mitotic spindle pole (GO:0097431)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle pole centrosome (GO:0031616)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Chromosome passenger complex (GO:0032133)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centriole (GO:0005814)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Condensed nuclear chromosome, centromeric region (GO:0000780)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Axon hillock (GO:0043203)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cilium (GO:0005929)	0.657	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.996

Q86XR8

(UniProtKB/Swiss-Prot/P) Details

Centrosomal protein of 57 kDa

Q9Y520

Interaction Score

0.996

P78362

(UniProtKB/Swiss-Prot/P) Details

SRSF protein kinase 2

Q9Y520

Interaction Score

0.996

P04150

(UniProtKB/Swiss-Prot/P) Details

Glucocorticoid receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.972	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	0.972	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle (GO:0005819)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	0.999	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.996

P19784

(UniProtKB/Swiss-Prot/P) Details

Casein kinase II subunit alpha'

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.996	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	PcG protein complex (GO:0031519)	0.996	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Acrosomal vesicle (GO:0001669)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromatin (GO:0000785)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.996

P04637

(UniProtKB/Swiss-Prot/P) Details

Cellular tumor antigen p53

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.972	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.972	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear matrix (GO:0016363)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	PML body (GO:0016605)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Transcription factor TFIID complex (GO:0005669)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Replication fork (GO:0005657)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.995

P56945

(UniProtKB/Swiss-Prot/P) Details

Breast cancer anti-estrogen resistance protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Ruffle (GO:0001726)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.995

P22087

(UniProtKB/Swiss-Prot/P) Details

rRNA 2'-O-methyltransferase fibrillarin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Box C/D snoRNP complex (GO:0031428)	0.937	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Small-subunit processome (GO:0032040)	0.937	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Granular component (GO:0001652)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Dense fibrillar component (GO:0001651)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Cajal body (GO:0015030)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.937	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.995

Q9NVX0

(UniProtKB/Swiss-Prot/P) Details

HAUS augmin-like complex subunit 2

Q9Y520

Interaction Score

0.994

P61457

(UniProtKB/Swiss-Prot/P) Details

Pterin-4-alpha-carbinolamine dehydratase

Q9Y520

Interaction Score

0.993

Q14258

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin/ISG15 ligase TRIM25

Q9Y520

Interaction Score

0.992

Q8TAP6

(UniProtKB/Swiss-Prot/P) Details

Centrosomal protein of 76 kDa

Q9Y520

Interaction Score

0.991

Q9NRC8

(UniProtKB/Swiss-Prot/P) Details

NAD-dependent protein deacetylase sirtuin-7

Q9Y520

Interaction Score

0.991

Q96JJ6

(UniProtKB/Swiss-Prot/P) Details

Junctophilin-4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.897	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Junctional membrane complex (GO:0030314)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Junctional sarcoplasmic reticulum membrane (GO:0014701)	0.897	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.897	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.79	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.79	Unknown: unspecified method	The Human Protein Atlas	PubMed
Secretory-pathway	Smooth endoplasmic reticulum (GO:0005790)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic shaft (GO:0043198)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.931	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.931	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.99

P04629

(UniProtKB/Swiss-Prot/P) Details

High affinity nerve growth factor receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.897	Unknown: unspecified method	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.897	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.994	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.994	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Late endosome membrane (GO:0031902)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.897	Predicted: pTarget method	LOCATE	PubMed
Membrane	Dendrite (GO:0030425)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.99

Q00987

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase Mdm2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.972	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.972	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.972	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Secretory-pathway	Endocytic vesicle membrane (GO:0030666)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.51	Unknown: traceable author statement	GO	PubMed
Membrane	Synapse (GO:0045202)	0.51	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.988

P08621

(UniProtKB/Swiss-Prot/P) Details

U1 small nuclear ribonucleoprotein 70 kDa

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	0.972	Experimental: experimental	Organelle	PubMed
Cytosol	U1 snRNP (GO:0005685)	0.972	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Spliceosomal complex (GO:0005681)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Precatalytic spliceosome (GO:0071011)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	U2-type prespliceosome (GO:0071004)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Commitment complex (GO:0000243)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.983

Q5U0Q1

(UniProtKB/TrEmbl/P) Details

Ras-GTPase-activating protein SH3-domain-binding protein, isoform CRA_a

Q9Y520

Interaction Score

0.982

Q8TEL6

(UniProtKB/Swiss-Prot/P) Details

Short transient receptor potential channel 4-associated protein

Q9Y520

Interaction Score

0.98

Q9NR22

(UniProtKB/Swiss-Prot/P) Details

Protein arginine N-methyltransferase 8

Q9Y520

Interaction Score

0.979

Q01167

(UniProtKB/Swiss-Prot/P) Details

Forkhead box protein K2

Q9Y520

Interaction Score

0.977

H3BP16

(UniProtKB/TrEmbl/P) Details

HAUS augmin-like complex subunit 2

Q9Y520

Interaction Score

0.976

P27824

(UniProtKB/Swiss-Prot/P) Details

Calnexin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.966	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Ribosome (GO:0005840)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Rough endoplasmic reticulum (GO:0005791)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Smooth endoplasmic reticulum (GO:0005790)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Integral to lumenal side of endoplasmic reticulum membrane (GO:0071556)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum quality control compartment (GO:0044322)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Melanosome (GO:0042470)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite cytoplasm (GO:0032839)	0.966	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	0.966	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	0.966	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.96	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.966	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.966	Experimental: experimental	eSLDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.657	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.972

Q15274

(UniProtKB/Swiss-Prot/P) Details

Nicotinate-nucleotide pyrophosphorylase [carboxylating]

Q9Y520

Interaction Score

0.968

Q08380

(UniProtKB/Swiss-Prot/P) Details

Galectin-3-binding protein

Q9Y520

Interaction Score

0.967

Q92731

(UniProtKB/Swiss-Prot/P) Details

Estrogen receptor beta

Q9Y520

Interaction Score

0.963

Q6ZVN7

(UniProtKB/Swiss-Prot/P) Details

Putative protein SEM1, isoform 2

Q9Y520

Interaction Score

0.963

Q9BXB1

(UniProtKB/Swiss-Prot/P) Details

Leucine-rich repeat-containing G-protein coupled receptor 4

Q9Y520

Interaction Score

0.96

P13612

(UniProtKB/Swiss-Prot/P) Details

Integrin alpha-4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Growth cone (GO:0030426)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	1	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.51	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.959

P53611

(UniProtKB/Swiss-Prot/P) Details

Geranylgeranyl transferase type-2 subunit beta

Q9Y520

Interaction Score

0.932

P23246

(UniProtKB/Swiss-Prot/P) Details

Splicing factor, proline- and glutamine-rich

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear matrix (GO:0016363)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Paraspeckles (GO:0042382)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	RNA polymerase II transcription factor complex (GO:0090575)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Chromatin (GO:0000785)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendrite cytoplasm (GO:0032839)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

Q9Y520

Interaction Score

0.928

Q53GA5

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Q9Y520

Interaction Score

0.91

Q8N8Y5

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 41 homolog

Q9Y520

Interaction Score

0.907

Q96JN0

(UniProtKB/Swiss-Prot/P) Details

Ligand-dependent corepressor

Q9Y520

Interaction Score

0.843

Q6ZP53

(UniProtKB/TrEmbl/P) Details

cDNA FLJ26493 fis, clone KDN06317, highly similar to Ras-GTPase-activating protein binding protein 1

Q9Y520

Interaction Score

0.82

A0A0G2JH32

(UniProtKB/TrEmbl/P) Details

Zinc finger protein 41 homolog

Q9Y520

Interaction Score

0.79

P60896

(UniProtKB/Swiss-Prot/P) Details

26S proteasome complex subunit SEM1

Q9Y520

Interaction Score

0.79

A0A087WV22

(UniProtKB/TrEmbl/P) Details

60S ribosomal protein L10

Q9Y520

Interaction Score

0.79

B7ZVW6

(UniProtKB/TrEmbl/P) Details

26S proteasome complex subunit SEM1

Q9Y520

Interaction Score

0.789

Q13148

(UniProtKB/Swiss-Prot/P) Details

TAR DNA-binding protein 43

Q9Y520

Interaction Score

0.752

A0A024R730

(UniProtKB/TrEmbl/P) Details

Cystic fibrosis transmembrane conductance regulator

Q9Y520

Interaction Score

0.752

X5DR71

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase receptor

Q9Y520

Interaction Score

0.7

Q9BQA5

(UniProtKB/Swiss-Prot/P) Details

Histone H4 transcription factor

Q9Y520

Interaction Score

0.696

Q92858

(UniProtKB/Swiss-Prot/P) Details

Protein atonal homolog 1

Q9Y520

Interaction Score

0.658

Q86VG2

(UniProtKB/TrEmbl/P) Details

Splicing factor proline/glutamine-rich

Q9Y520

Interaction Score

0.597

Q8WYQ3

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial

Q9Y520

Interaction Score

0.56

A0A087WT22

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Q9Y520

Interaction Score

0.56

A0A087WXZ1

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Q9Y520

Interaction Score

0.56

A0A087X1Q1

(UniProtKB/TrEmbl/P) Details

Cellular tumor antigen p53

Q9Y520

Interaction Score

0.49

Q9UFS1

(UniProtKB/TrEmbl/P) Details

SNRNP70 protein

Q9Y520

Interaction Score

0.21

Q6IB63

(UniProtKB/TrEmbl/P) Details

RABGGTB protein

Q9Y520

Interaction Score

0.21

Q59ER8

(UniProtKB/TrEmbl/P) Details

Leucine-rich repeat-containing G protein-coupled receptor 4 variant

Q9Y520

Interaction Score

Q6IBB7

(UniProtKB/TrEmbl/P) Details

SHFM1 protein

Q9Y520

Interaction Score

B5MBW9

(UniProtKB/TrEmbl/P) Details

Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial

Q9Y520

Interaction Score

Q59GT2

(UniProtKB/TrEmbl/P) Details

Protein arginine N-methyltransferase 4 variant

⇦ Back to the Search Page
⇦ Back to Starting Page

Q9Y520

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

Q9Y520

P11142

Heat shock cognate 71 kDa protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y520

Q13283

Ras GTPase-activating protein-binding protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y520

Q15717

ELAV-like protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y520

Q9H0R8

Gamma-aminobutyric acid receptor-associated protein-like 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y520

P27635

60S ribosomal protein L10

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y520

Q9NQC7

Ubiquitin carboxyl-terminal hydrolase CYLD

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y520

O60260

E3 ubiquitin-protein ligase parkin

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y520

P49841

Glycogen synthase kinase-3 beta

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y520

P19320

Vascular cell adhesion protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y520

P13569

Cystic fibrosis transmembrane conductance regulator

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y520

Q96GD4

Aurora kinase B

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y520

O14965

Aurora kinase A

Localizations:

Interaction Source Database:

Interaction Source Publication:

Q9Y520