O76258

Tumor Susceptibility Gene homolog    //   UniProt Profile 

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Species

 C. elegans

Number of Interactions

 12 / 20

Average Interaction Score

 0.736

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.94 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway ESCRT I complex (GO:0000813) 0.94 Predicted: inferred from physical interaction GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

O76258

Interaction Score
0.966

O44158

(UniProtKB/TrEmbl/P) Details

Related to yeast Vacuolar Protein Sorting factor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.982 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.8 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.982 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway ESCRT I complex (GO:0000813) 0.982 Predicted: inferred from physical interaction GO PubMed 

Interaction Source Database:

BioGRID, CCSB, IntAct

Interaction Source Publication:

PubMed , PubMed 

O76258

Interaction Score
0.964

Q17796

(UniProtKB/TrEmbl/P) Details

Hepatocyte Growth factor-Regulated TK Substrate (HRS) family

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Early endosome (GO:0005769) 0.988 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.988 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway ESCRT-0 complex (GO:0033565) 0.988 Predicted: inferred from physical interaction GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

O76258

Interaction Score
0.96

Q17687

(UniProtKB/TrEmbl/P) Details

MVB (Yeast MultiVesicular Body sorting factor) related

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.94 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.94 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway ESCRT I complex (GO:0000813) 0.94 Predicted: inferred from physical interaction GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O76258

Interaction Score
0.911

Q8MQ04

(UniProtKB/TrEmbl/P) Details

Kinesin-like protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

O76258

Interaction Score
0.881

Q09248

(UniProtKB/Swiss-Prot/P) Details

Probable dynactin subunit 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.86 Unknown: HDA GO PubMed 
Cytosol Spindle microtubule (GO:0005876) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Dynein complex (GO:0030286) 1 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Dynactin complex (GO:0005869) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Pericentriolar material (GO:0000242) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Kinetochore (GO:0000776) 0.86 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

O76258

Interaction Score
0.826

Q9XVU8

(UniProtKB/TrEmbl/P) Details

AcTiniN

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed , PubMed 

O76258

Interaction Score
0.74

Q9UA61

(UniProtKB/TrEmbl/P) Details

Galectin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O76258

Interaction Score
0.7

Q8MQ03

(UniProtKB/TrEmbl/P) Details

Kinesin-like protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Midbody (GO:0030496) 0.8 Experimental: inferred from direct assay GO PubMed 
Cytosol Cleavage furrow (GO:0032154) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Spindle midzone (GO:0051233) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Mitotic spindle midzone (GO:1990023) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Kinesin complex (GO:0005871) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule (GO:0005874) 1 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O76258

Interaction Score
0.692

Q23158

(UniProtKB/TrEmbl/P) Details

AcTiniN

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Striated muscle dense body (GO:0055120) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Striated muscle thin filament (GO:0005865) 0.988 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O76258

Interaction Score
0.49

Q21592

(UniProtKB/TrEmbl/P) Details

Kinesin Light Chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O76258

Interaction Score
0.49

Q9GYT4

(UniProtKB/TrEmbl/P) Details

ARRestin Domain protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct, CCSB

Interaction Source Publication:

PubMed 

O76258

Interaction Score
0.21

H9G2T2

(UniProtKB/TrEmbl/P) Details

Kinesin Light Chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Kinesin complex (GO:0005871) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015