Q17446

Mitogen-activated protein kinase pmk-1    //   UniProt Profile 

Custom Settings: Use these controls to filter the data displayed on this page. The parameters apply to both the query protein and its interactors. Details







The (filtered) results are available for download, see the help for details. Download The Results

Species

 C. elegans

Number of Interactions

 28 / 40

Average Interaction Score

 0.759

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.982 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 

First-Neighbour Network Visualization

Toggle Display

The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q17446

Interaction Score
0.998

P91001

(UniProtKB/Swiss-Prot/P) Details

COP9 signalosome complex subunit 5

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.992 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Signalosome (GO:0008180) 0.996 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol A band (GO:0031672) 0.992 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

CCSB, BioGRID, IntAct, DIP

Interaction Source Publication:

PubMed , PubMed 

Q17446

Interaction Score
0.997

Q86G90

(UniProtKB/TrEmbl/P) Details

Nuclear Pore complex Protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.992 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.992 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.992 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nuclear pore (GO:0005643) 0.94 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 0.992 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID, IntAct, CCSB

Interaction Source Publication:

PubMed , PubMed 

Q17446

Interaction Score
0.992

Q22436

(UniProtKB/TrEmbl/P) Details

SeQueSTosome related

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Aggresome (GO:0016235) 0.995 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.995 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.995 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Autophagic vacuole (GO:0005776) 0.995 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct, BioGRID, CCSB, DIP

Interaction Source Publication:

PubMed , PubMed 

Q17446

Interaction Score
0.991

O18158

(UniProtKB/Swiss-Prot/P) Details

UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.94 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

DIP, BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q17446

Interaction Score
0.985

Q965G5

(UniProtKB/Swiss-Prot/P) Details

MAP kinase-activated protein kinase mak-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Perikaryon (GO:0043204) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.958 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.8 Experimental: inferred from direct assay GO PubMed 
Membrane Cell junction (GO:0030054) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Membrane Synapse (GO:0045202) 0.86 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

CCSB, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q17446

Interaction Score
0.985

Q18846

(UniProtKB/Swiss-Prot/P) Details

Putative ribosomal protein S6 kinase alpha-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

DIP, IntAct, CCSB, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q17446

Interaction Score
0.982

Q9GRZ1

(UniProtKB/TrEmbl/P) Details

Microtubule End Binding Protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cell cortex (GO:0005938) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Astral microtubule (GO:0000235) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Microtubule plus end (GO:0035371) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct, DIP

Interaction Source Publication:

PubMed 

Q17446

Interaction Score
0.979

P34766

(UniProtKB/Swiss-Prot/P) Details

Homeobox protein pal-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Condensed nuclear chromosome (GO:0000794) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Condensed chromosome kinetochore (GO:0000777) 0.992 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, IntAct, CCSB

Interaction Source Publication:

PubMed , PubMed 

Q17446

Interaction Score
0.973

O62305

(UniProtKB/Swiss-Prot/P) Details

Calcium/calmodulin-dependent protein kinase type II

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Perikaryon (GO:0043204) 0.937 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.937 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.937 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Membrane Neuron projection (GO:0043005) 0.8 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

DIP, CCSB, BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

Q17446

Interaction Score
0.97

P0DM42

(UniProtKB/Swiss-Prot/P) Details

Actin-3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Striated muscle thin filament (GO:0005865) 0.988 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

DIP, BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q17446

Interaction Score
0.964

O16454

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Lysosome (GO:0005764) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Lysosome (GO:0005764) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct, DIP, BioGRID

Interaction Source Publication:

PubMed 

Q17446

Interaction Score
0.955

Q6A2D2

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

CCSB, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q17446

Interaction Score
0.953

P0DM41

(UniProtKB/Swiss-Prot/P) Details

Actin-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.971 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.971 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.971 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct, DIP, BioGRID

Interaction Source Publication:

PubMed 

Q17446

Interaction Score
0.943

G5ED84

(UniProtKB/Swiss-Prot/P) Details

Kelch-like protein 8

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cul3-RING ubiquitin ligase complex (GO:0031463) 0.96 Experimental: inferred from direct assay GO PubMed 
Cytosol Neuronal cell body (GO:0043025) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Neuron projection (GO:0043005) 0.972 Experimental: inferred from direct assay GO PubMed 
Membrane Postsynaptic density (GO:0014069) 0.972 Experimental: inferred from direct assay GO PubMed 
Membrane Cell junction (GO:0030054) 0.972 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q17446

Interaction Score
0.923

Q9GRZ0

(UniProtKB/TrEmbl/P) Details

Microtubule End Binding Protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Microtubule (GO:0005874) 0.79 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q17446

Interaction Score
0.901

O45436

(UniProtKB/Swiss-Prot/P) Details

Nuclear hormone receptor family member nhr-4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.958 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

CCSB, BioGRID, IntAct, DIP

Interaction Source Publication:

PubMed , PubMed 

Q17446

Interaction Score
0.893

Q21021

(UniProtKB/TrEmbl/P) Details

Nuclear Pore complex Protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID, CCSB, DIP

Interaction Source Publication:

PubMed , PubMed 

Q17446

Interaction Score
0.808

G5EFL9

(UniProtKB/TrEmbl/P) Details

BHLH-PAS factor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.86 Unknown: inferred by curator GO PubMed 
Nucleus RNA polymerase II transcription factor complex (GO:0090575) 0.86 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q17446

Interaction Score
0.687

Q9U2D9

(UniProtKB/Swiss-Prot/P) Details

Glycogen [starch] synthase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID, DIP, IntAct, CCSB

Interaction Source Publication:

PubMed , PubMed 

Q17446

Interaction Score
0.687

Q93637

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

CCSB, BioGRID, DIP, IntAct

Interaction Source Publication:

PubMed , PubMed 

Q17446

Interaction Score
0.687

Q93636

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID, CCSB

Interaction Source Publication:

PubMed , PubMed 

Q17446

Interaction Score
0.687

O61900

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q17446

Interaction Score
0.658

Q95QC2

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrial large ribosomal subunit (GO:0005762) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

DIP, BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q17446

Interaction Score
0.658

Q9XW83

(UniProtKB/TrEmbl/P) Details

GRound-Like

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID, IntAct, DIP

Interaction Source Publication:

PubMed 

Q17446

Interaction Score
0

Q20772

(UniProtKB/Swiss-Prot/P) Details

Probable glutaryl-CoA dehydrogenase, mitochondrial

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.958 Experimental: experimental eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrial matrix (GO:0005759) 0.958 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct, DIP, CCSB, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q17446

Interaction Score
0

Q19300

(UniProtKB/TrEmbl/P) Details

FAR (Factor ARrest) Like

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct, CCSB, DIP, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q17446

Interaction Score
0

Q5DX39

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

CCSB, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q17446

Interaction Score
0

O02161

(UniProtKB/Swiss-Prot/P) Details

Probable mitochondrial import inner membrane translocase subunit tin-44

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.982 Experimental: experimental eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrial inner membrane (GO:0005743) 0.982 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

IntAct, CCSB, DIP, BioGRID

Interaction Source Publication:

PubMed , PubMed 

⇦ Back to the Search Page
⇦ Back to Starting Page

ComPPI is published in Nucleic Acids Research Database Issue 2015