P0DM41

Actin-1    //   UniProt Profile 

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Species

 C. elegans

Number of Interactions

 15 / 18

Average Interaction Score

 0.718

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.971 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.971 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.971 Unknown: inferred from electronic annotation GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

P0DM41

Interaction Score
0.97

P10984

(UniProtKB/Swiss-Prot/P) Details

Actin-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cell cortex (GO:0005938) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Actin filament (GO:0005884) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed , PubMed 

P0DM41

Interaction Score
0.967

Q9U9Y8

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine kinase NLK

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cell cortex (GO:0005938) 0.996 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

CCSB, BioGRID, IntAct, DIP

Interaction Source Publication:

PubMed , PubMed 

P0DM41

Interaction Score
0.959

P0DM42

(UniProtKB/Swiss-Prot/P) Details

Actin-3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Striated muscle thin filament (GO:0005865) 0.988 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

CCSB, IntAct, BioGRID

Interaction Source Publication:

PubMed , PubMed , PubMed 

P0DM41

Interaction Score
0.953

O45815

(UniProtKB/TrEmbl/P) Details

ACTin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Terminal web (GO:1990357) 0.982 Experimental: inferred from direct assay GO PubMed 
Membrane Microvillar actin bundle (GO:0097516) 0.8 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

CCSB, BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed , PubMed 

P0DM41

Interaction Score
0.953

Q17446

(UniProtKB/Swiss-Prot/P) Details

Mitogen-activated protein kinase pmk-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.982 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

DIP, IntAct, BioGRID

Interaction Source Publication:

PubMed 

P0DM41

Interaction Score
0.953

P10986

(UniProtKB/Swiss-Prot/P) Details

Actin-4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Striated muscle thin filament (GO:0005865) 0.982 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.982 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Membrane raft (GO:0045121) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed , PubMed 

P0DM41

Interaction Score
0.932

Q07750

(UniProtKB/Swiss-Prot/P) Details

Actin-depolymerizing factor 1, isoforms a/b

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Striated muscle thin filament (GO:0005865) 0.96 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct, CCSB

Interaction Source Publication:

PubMed 

P0DM41

Interaction Score
0.679

Q18033

(UniProtKB/TrEmbl/P) Details

THO Complex (Transcription factor/nuclear export) subunit

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.973 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus THO complex (GO:0000347) 0.973 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus THO complex part of transcription export complex (GO:0000445) 0.973 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct, BioGRID, DIP

Interaction Source Publication:

PubMed 

P0DM41

Interaction Score
0.679

Q07749

(UniProtKB/Swiss-Prot/P) Details

Actin-depolymerizing factor 2, isoform c

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

CCSB

Interaction Source Publication:

PubMed 

P0DM41

Interaction Score
0.679

O17915

(UniProtKB/Swiss-Prot/P) Details

GTP-binding nuclear protein ran-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 0.987 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.987 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Condensed chromosome kinetochore (GO:0000777) 0.987 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct, BioGRID, DIP

Interaction Source Publication:

PubMed 

P0DM41

Interaction Score
0.679

Q95ZL1

(UniProtKB/TrEmbl/P) Details

Actin-4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P0DM41

Interaction Score
0.679

Q6A8K1

(UniProtKB/TrEmbl/P) Details

Actin-4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P0DM41

Interaction Score
0.679

O76368

(UniProtKB/Swiss-Prot/P) Details

Putative cuticle collagen 99

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Collagen (GO:0005581) 0.958 Unknown: non-traceable author statement GO PubMed 
Membrane Fully spanning plasma membrane (GO:0044214) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Neuromuscular junction (GO:0031594) 0.96 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

DIP

Interaction Source Publication:

PubMed 

P0DM41

Interaction Score
0

G5EF34

(UniProtKB/TrEmbl/P) Details

CRiM (Cysteine Rich motor neuron protein) homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

P0DM41

Interaction Score
0

O45166

(UniProtKB/Swiss-Prot/P) Details

Folate-like transporter 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Integral to membrane (GO:0016021) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, DIP, IntAct

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015