Q8N4Q3

Similar to Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6    //   UniProt Profile 

Custom Settings: Use these controls to filter the data displayed on this page. The parameters apply to both the query protein and its interactors. Details







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Species

H. sapiens

Number of Interactions

48 / 67

Average Interaction Score

0.653

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

First-Neighbour Network Visualization

Toggle Display
Q14161O60711P32121Q13153P63000Q9NZQ3Q13177Q93009Q14155Q68DZ5Q9H7C4Q15599P78527P60953Q96D09Q6UXF1B3KT64P22681Q9NVF7Q15052Q68DM7Q59EM5B7Z5P7Q5W9H1Q9NPJ6Q9Y2X7Q9UK33P30613O43639Q99963P36897P53611F8W822Q13444B4DY26F8VXI9A4D2P1K7ENA6Q6FI58Q6U8A4P05362P37173A3QNQ0Q6IB63A4D2P0D2JYI1Q5T7S2B4DXN7Q8N4Q3

The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q8N4Q3

Interaction Score
0.909

Q14161

(UniProtKB/Swiss-Prot/P) Details

ARF GTPase-activating protein GIT2

Q8N4Q3

Interaction Score
0.908

O60711

(UniProtKB/Swiss-Prot/P) Details

Leupaxin

Q8N4Q3

Interaction Score
0.907

P32121

(UniProtKB/Swiss-Prot/P) Details

Beta-arrestin-2

Q8N4Q3

Interaction Score
0.906

Q13153

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase PAK 1

Q8N4Q3

Interaction Score
0.902

P63000

(UniProtKB/Swiss-Prot/P) Details

Ras-related C3 botulinum toxin substrate 1

Q8N4Q3

Interaction Score
0.901

Q9NZQ3

(UniProtKB/Swiss-Prot/P) Details

NCK-interacting protein with SH3 domain

Q8N4Q3

Interaction Score
0.901

Q13177

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase PAK 2

Q8N4Q3

Interaction Score
0.897

Q93009

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase 7

Q8N4Q3

Interaction Score
0.89

Q14155

(UniProtKB/Swiss-Prot/P) Details

Rho guanine nucleotide exchange factor 7

Q8N4Q3

Interaction Score
0.888

Q68DZ5

(UniProtKB/TrEmbl/P) Details

cDNA FLJ58316, highly similar to Beta-arrestin-2

Q8N4Q3

Interaction Score
0.887

Q9H7C4

(UniProtKB/Swiss-Prot/P) Details

Syncoilin

Q8N4Q3

Interaction Score
0.882

Q15599

(UniProtKB/Swiss-Prot/P) Details

Na(+)/H(+) exchange regulatory cofactor NHE-RF2

Q8N4Q3

Interaction Score
0.881

P78527

(UniProtKB/Swiss-Prot/P) Details

DNA-dependent protein kinase catalytic subunit

Q8N4Q3

Interaction Score
0.868

P60953

(UniProtKB/Swiss-Prot/P) Details

Cell division control protein 42 homolog

Q8N4Q3

Interaction Score
0.867

Q96D09

(UniProtKB/Swiss-Prot/P) Details

G-protein coupled receptor-associated sorting protein 2

Q8N4Q3

Interaction Score
0.856

Q6UXF1

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 108

Q8N4Q3

Interaction Score
0.856

B3KT64

(UniProtKB/TrEmbl/P) Details

cDNA FLJ37731 fis, clone BRHIP2020743, moderately similar to Transmembrane protein 108

Q8N4Q3

Interaction Score
0.846

P22681

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase CBL

Q8N4Q3

Interaction Score
0.846

Q9NVF7

(UniProtKB/Swiss-Prot/P) Details

F-box only protein 28

Q8N4Q3

Interaction Score
0.843

Q15052

(UniProtKB/Swiss-Prot/P) Details

Rho guanine nucleotide exchange factor 6

Q8N4Q3

Interaction Score
0.815

Q68DM7

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686G01261

Q8N4Q3

Interaction Score
0.806

Q59EM5

(UniProtKB/TrEmbl/P) Details

Arrestin beta 2 isoform 1 variant

Q8N4Q3

Interaction Score
0.806

B7Z5P7

(UniProtKB/TrEmbl/P) Details

cDNA FLJ51550, highly similar to Leupaxin

Q8N4Q3

Interaction Score
0.74

Q5W9H1

(UniProtKB/TrEmbl/P) Details

KIAA0142 splice variant 1

Q8N4Q3

Interaction Score
0.7

Q9NPJ6

(UniProtKB/Swiss-Prot/P) Details

Mediator of RNA polymerase II transcription subunit 4

Q8N4Q3

Interaction Score
0.698

Q9Y2X7

(UniProtKB/Swiss-Prot/P) Details

ARF GTPase-activating protein GIT1

Q8N4Q3

Interaction Score
0.698

Q9UK33

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 580

Q8N4Q3

Interaction Score
0.691

P30613

(UniProtKB/Swiss-Prot/P) Details

Pyruvate kinase PKLR

Q8N4Q3

Interaction Score
0.686

O43639

(UniProtKB/Swiss-Prot/P) Details

Cytoplasmic protein NCK2

Q8N4Q3

Interaction Score
0.681

Q99963

(UniProtKB/Swiss-Prot/P) Details

Endophilin-A3

Q8N4Q3

Interaction Score
0.672

P36897

(UniProtKB/Swiss-Prot/P) Details

TGF-beta receptor type-1

Q8N4Q3

Interaction Score
0.671

P53611

(UniProtKB/Swiss-Prot/P) Details

Geranylgeranyl transferase type-2 subunit beta

Q8N4Q3

Interaction Score
0.658

F8W822

(UniProtKB/TrEmbl/P) Details

ARF GTPase-activating protein GIT2

Q8N4Q3

Interaction Score
0.602

Q13444

(UniProtKB/Swiss-Prot/P) Details

Disintegrin and metalloproteinase domain-containing protein 15

Q8N4Q3

Interaction Score
0.56

B4DY26

(UniProtKB/TrEmbl/P) Details

Receptor protein serine/threonine kinase

Q8N4Q3

Interaction Score
0.56

F8VXI9

(UniProtKB/TrEmbl/P) Details

ARF GTPase-activating protein GIT2

Q8N4Q3

Interaction Score
0.56

A4D2P1

(UniProtKB/TrEmbl/P) Details

Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1), isoform CRA_a

Q8N4Q3

Interaction Score
0.56

K7ENA6

(UniProtKB/TrEmbl/P) Details

Beta-arrestin-2

Q8N4Q3

Interaction Score
0.49

Q6FI58

(UniProtKB/TrEmbl/P) Details

G protein-coupled receptor kinase-interactor 2 isoform 4 variant

Q8N4Q3

Interaction Score
0.49

Q6U8A4

(UniProtKB/TrEmbl/P) Details

Ubiquitin-specific protease 7 isoform

Q8N4Q3

Interaction Score
0.357

P05362

(UniProtKB/Swiss-Prot/P) Details

Intercellular adhesion molecule 1

Q8N4Q3

Interaction Score
0.21

P37173

(UniProtKB/Swiss-Prot/P) Details

TGF-beta receptor type-2

Q8N4Q3

Interaction Score
0

A3QNQ0

(UniProtKB/TrEmbl/P) Details

TGF-beta receptor type-2

Q8N4Q3

Interaction Score
0

Q6IB63

(UniProtKB/TrEmbl/P) Details

RABGGTB protein

Q8N4Q3

Interaction Score
0

A4D2P0

(UniProtKB/TrEmbl/P) Details

Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1), isoform CRA_e

Q8N4Q3

Interaction Score
0

D2JYI1

(UniProtKB/TrEmbl/P) Details

TGF-beta receptor type-2

Q8N4Q3

Interaction Score
0

Q5T7S2

(UniProtKB/TrEmbl/P) Details

Receptor protein serine/threonine kinase

Q8N4Q3

Interaction Score
0

B4DXN7

(UniProtKB/TrEmbl/P) Details

Receptor protein serine/threonine kinase

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ComPPI is published in Nucleic Acids Research Database Issue 2015