Q18033

THO Complex (Transcription factor/nuclear export) subunit    //   UniProt Profile 

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Species

 C. elegans

Number of Interactions

 19 / 25

Average Interaction Score

 0.668

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.973 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus THO complex (GO:0000347) 0.973 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus THO complex part of transcription export complex (GO:0000445) 0.973 Predicted: inferred from biological aspect of ancestor GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q18033

Interaction Score
0.988

Q21215

(UniProtKB/Swiss-Prot/P) Details

Guanine nucleotide-binding protein subunit beta-2-like 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cell body (GO:0044297) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.998 Experimental: inferred from direct assay GO PubMed 
Cytosol Ribosome (GO:0005840) 0.998 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.988 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nuclear envelope (GO:0005635) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Centrosome (GO:0005813) 0.998 Experimental: inferred from direct assay GO PubMed 
Nucleus Kinetochore (GO:0000776) 0.988 Experimental: inferred from direct assay GO PubMed 
Membrane Growth cone (GO:0030426) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Axon (GO:0030424) 0.96 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct, DIP, BioGRID

Interaction Source Publication:

PubMed 

Q18033

Interaction Score
0.982

P34766

(UniProtKB/Swiss-Prot/P) Details

Homeobox protein pal-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.992 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Condensed nuclear chromosome (GO:0000794) 0.992 Experimental: inferred from direct assay GO PubMed 
Nucleus Condensed chromosome kinetochore (GO:0000777) 0.992 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, CCSB, IntAct

Interaction Source Publication:

PubMed , PubMed 

Q18033

Interaction Score
0.968

P34429

(UniProtKB/Swiss-Prot/P) Details

Probable replication factor C subunit 5

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.995 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.995 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 0.995 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus DNA replication factor C complex (GO:0005663) 0.995 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

DIP, BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q18033

Interaction Score
0.961

P49632

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-60S ribosomal protein L40

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Ribosome (GO:0005840) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q18033

Interaction Score
0.93

P0CG71

(UniProtKB/Swiss-Prot/P) Details

Polyubiquitin-A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.937 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q18033

Interaction Score
0.915

P41829

(UniProtKB/Swiss-Prot/P) Details

Nuclear hormone receptor family member nhr-6

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.94 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct, BioGRID, DIP

Interaction Source Publication:

PubMed 

Q18033

Interaction Score
0.884

O44480

(UniProtKB/Swiss-Prot/P) Details

60S ribosomal protein L18a

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosolic large ribosomal subunit (GO:0022625) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q18033

Interaction Score
0.837

P19974

(UniProtKB/Swiss-Prot/P) Details

Cytochrome c 2.1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.982 Experimental: experimental Organelle PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrial intermembrane space (GO:0005758) 0.982 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Membrane Respiratory chain (GO:0070469) 0.3 Unknown: inferred by curator GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q18033

Interaction Score
0.769

Q9N4B8

(UniProtKB/Swiss-Prot/P) Details

Nuclear hormone receptor family member nhr-41

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

DIP, IntAct

Interaction Source Publication:

PubMed 

Q18033

Interaction Score
0.692

P0DM42

(UniProtKB/Swiss-Prot/P) Details

Actin-3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Striated muscle thin filament (GO:0005865) 0.988 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID, DIP, IntAct

Interaction Source Publication:

PubMed 

Q18033

Interaction Score
0.681

O45603

(UniProtKB/TrEmbl/P) Details

MEiosis-to-MItosis transition associated

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID, IntAct, DIP

Interaction Source Publication:

PubMed 

Q18033

Interaction Score
0.679

P0DM41

(UniProtKB/Swiss-Prot/P) Details

Actin-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.971 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.971 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytoskeleton (GO:0005856) 0.971 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID, DIP, IntAct

Interaction Source Publication:

PubMed 

Q18033

Interaction Score
0.637

P61866

(UniProtKB/Swiss-Prot/P) Details

60S ribosomal protein L12

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytosolic large ribosomal subunit (GO:0022625) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct, DIP, BioGRID

Interaction Source Publication:

PubMed 

Q18033

Interaction Score
0.49

Q20877

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

IntAct, DIP, BioGRID

Interaction Source Publication:

PubMed 

Q18033

Interaction Score
0.49

Q09279

(UniProtKB/Swiss-Prot/P) Details

Uncharacterized protein C45G9.6

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

Q18033

Interaction Score
0.49

O76368

(UniProtKB/Swiss-Prot/P) Details

Putative cuticle collagen 99

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Collagen (GO:0005581) 0.958 Unknown: non-traceable author statement GO PubMed 
Membrane Fully spanning plasma membrane (GO:0044214) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Neuromuscular junction (GO:0031594) 0.96 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

DIP

Interaction Source Publication:

PubMed 

Q18033

Interaction Score
0.292

Q3V5L2

(UniProtKB/TrEmbl/P) Details

Nuclear Hormone Receptor family

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q18033

Interaction Score
0

O45078

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Membrane Membrane raft (GO:0045121) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct, DIP, BioGRID

Interaction Source Publication:

PubMed 

Q18033

Interaction Score
0

G5EG61

(UniProtKB/TrEmbl/P) Details

p-GlycoProtein related

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Integral to membrane (GO:0016021) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015