Q22601

AP-2 complex subunit alpha    //   UniProt Profile 

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Species

C. elegans

Number of Interactions

5 / 10

Average Interaction Score

0.921

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Coated pit (GO:0005905) 0.937 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.937 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.937 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endocytic vesicle (GO:0030139) 0.988 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Clathrin-coated endocytic vesicle (GO:0045334) 0.988 Experimental: inferred from direct assay GO PubMed 
Membrane Clathrin adaptor complex (GO:0030131) 0.994 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Experimental: inferred from direct assay GO PubMed 
Membrane Synapse (GO:0045202) 0.994 Experimental: inferred from direct assay GO PubMed 
Membrane Presynaptic periactive zone (GO:0036062) 0.994 Experimental: inferred from direct assay GO PubMed 

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Interactions

All Details

Q22601

Interaction Score
0.999

Q9GYH7

(UniProtKB/Swiss-Prot/P) Details

Receptor-mediated endocytosis protein 6

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 0.91 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Early endosome (GO:0005769) 0.96 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Clathrin-coated endocytic vesicle (GO:0045334) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.8 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

Q22601

Interaction Score
0.988

Q17796

(UniProtKB/TrEmbl/P) Details

Hepatocyte Growth factor-Regulated TK Substrate (HRS) family

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Early endosome (GO:0005769) 0.988 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.988 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway ESCRT-0 complex (GO:0033565) 0.988 Predicted: inferred from physical interaction GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q22601

Interaction Score
0.986

Q9BIF4

(UniProtKB/TrEmbl/P) Details

EHS-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Axon (GO:0030424) 0.992 Experimental: inferred from mutant phenotype GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.992 Experimental: inferred from direct assay GO PubMed 
Membrane Synapse (GO:0045202) 0.992 Experimental: inferred from mutant phenotype GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q22601

Interaction Score
0.825

Q9U2T9

(UniProtKB/TrEmbl/P) Details

ITSN (Intersectin) family

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q22601

Interaction Score
0.806

G5ECW9

(UniProtKB/TrEmbl/P) Details

Receptor Mediated Endocytosis

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Coated pit (GO:0005905) 0.86 Experimental: inferred from direct assay GO PubMed 
Cytosol Intracellular (GO:0005622) 0.86 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015