Q9BIF4

EHS-1    //   UniProt Profile 

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Species

 C. elegans

Number of Interactions

 27 / 40

Average Interaction Score

 0.417

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Axon (GO:0030424) 0.992 Experimental: inferred from mutant phenotype GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.992 Experimental: inferred from direct assay GO PubMed 
Membrane Synapse (GO:0045202) 0.992 Experimental: inferred from mutant phenotype GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

Q9BIF4

Interaction Score
0.988

P34574

(UniProtKB/Swiss-Prot/P) Details

Probable clathrin heavy chain 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cell cortex (GO:0005938) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Cytoplasmic vesicle (GO:0031410) 0.994 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endocytic vesicle (GO:0030139) 0.994 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Clathrin-coated endocytic vesicle (GO:0045334) 0.994 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Clathrin coat of trans-Golgi network vesicle (GO:0030130) 0.994 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Mitotic spindle (GO:0072686) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Clathrin complex (GO:0071439) 0.996 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.996 Experimental: inferred from direct assay GO PubMed 
Membrane Internal side of plasma membrane (GO:0009898) 0.996 Experimental: inferred from direct assay GO PubMed 
Membrane Clathrin coat of coated pit (GO:0030132) 0.996 Unknown: inferred from electronic annotation GO PubMed 
Membrane Apical plasma membrane (GO:0016324) 0.996 Experimental: inferred from direct assay GO PubMed 
Cytosol Vesicle (GO:0031982) 1 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0.986

Q22601

(UniProtKB/TrEmbl/P) Details

AP-2 complex subunit alpha

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Coated pit (GO:0005905) 0.937 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.937 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.937 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endocytic vesicle (GO:0030139) 0.988 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Clathrin-coated endocytic vesicle (GO:0045334) 0.988 Experimental: inferred from direct assay GO PubMed 
Membrane Clathrin adaptor complex (GO:0030131) 0.994 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.994 Experimental: inferred from direct assay GO PubMed 
Membrane Synapse (GO:0045202) 0.994 Experimental: inferred from direct assay GO PubMed 
Membrane Presynaptic periactive zone (GO:0036062) 0.994 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0.984

A5JYR4

(UniProtKB/TrEmbl/P) Details

DAB (Drosophila disabled) homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Cell cortex (GO:0005938) 0.992 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi-associated vesicle (GO:0005798) 0.96 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Clathrin-coated vesicle (GO:0030136) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane AP-1 adaptor complex (GO:0030121) 0.992 Experimental: inferred from direct assay GO PubMed 
Membrane AP-2 adaptor complex (GO:0030122) 0.992 Experimental: inferred from direct assay GO PubMed 
Membrane Extrinsic to internal side of plasma membrane (GO:0031234) 0.992 Experimental: inferred from direct assay GO PubMed 
Cytosol Vesicle (GO:0031982) 0.992 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

CCSB

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0.95

Q19951

(UniProtKB/Swiss-Prot/P) Details

Probable peroxisomal membrane protein PEX13

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Peroxisome (GO:0005777) 0.958 Experimental: experimental eSLDB PubMed 
Cytosol Peroxisome (GO:0005777) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Peroxisomal membrane (GO:0005778) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0.895

B1V8A0

(UniProtKB/Swiss-Prot/P) Details

Endophilin-A homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Synaptic vesicle (GO:0008021) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Membrane Membrane (GO:0016020) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Membrane Cell junction (GO:0030054) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Membrane Neuromuscular junction (GO:0031594) 0.902 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0.853

G5EE56

(UniProtKB/Swiss-Prot/P) Details

Tyrosine protein-kinase src-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Contractile fiber (GO:0043292) 0.8 Experimental: inferred from direct assay GO PubMed 
Membrane Cell projection (GO:0042995) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Membrane Phagocytic cup (GO:0001891) 0.86 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0.853

P90961

(UniProtKB/TrEmbl/P) Details

Clathrin light chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Clathrin vesicle coat (GO:0030125) 0.79 Predicted: inferred from biological aspect of ancestor GO PubMed 
Secretory-pathway Clathrin coat of trans-Golgi network vesicle (GO:0030130) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Membrane Periciliary membrane compartment (GO:1990075) 0.86 Experimental: inferred from direct assay GO PubMed 
Membrane Clathrin coat of coated pit (GO:0030132) 0.86 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0.794

O01498

(UniProtKB/Swiss-Prot/P) Details

Signal transducing adapter molecule 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.996 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endosome (GO:0005768) 0.996 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Early endosome (GO:0005769) 0.996 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway ESCRT-0 complex (GO:0033565) 0.996 Predicted: inferred from physical interaction GO PubMed 
Membrane Cilium (GO:0005929) 0.8 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0.794

Q94420

(UniProtKB/Swiss-Prot/P) Details

Protein maternal effect lethal 26

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol SCF ubiquitin ligase complex (GO:0019005) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cleavage furrow (GO:0032154) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytosol (GO:0005829) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cell cortex (GO:0005938) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Lysosome (GO:0005764) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol I band (GO:0031674) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol M band (GO:0031430) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Condensed chromosome (GO:0000793) 0.982 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0.784

Q7K7J0

(UniProtKB/TrEmbl/P) Details

GEX Interacting protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Integral to membrane (GO:0016021) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.79 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0.694

P03949

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein kinase abl-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Extrinsic to internal side of plasma membrane (GO:0031234) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed , PubMed 

Q9BIF4

Interaction Score
0.694

Q8MPT2

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0.694

Q21758

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0.298

Q9N4F3

(UniProtKB/TrEmbl/P) Details

AP complex subunit beta

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Clathrin adaptor complex (GO:0030131) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0

Q7YZG9

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0

Q17796

(UniProtKB/TrEmbl/P) Details

Hepatocyte Growth factor-Regulated TK Substrate (HRS) family

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Early endosome (GO:0005769) 0.988 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.988 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway ESCRT-0 complex (GO:0033565) 0.988 Predicted: inferred from physical interaction GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0

Q9U2T9

(UniProtKB/TrEmbl/P) Details

ITSN (Intersectin) family

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID, IntAct, CCSB

Interaction Source Publication:

PubMed , PubMed , PubMed 

Q9BIF4

Interaction Score
0

Q7YZG8

(UniProtKB/TrEmbl/P) Details

AP complex subunit beta

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0

Q18603

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Extracellular Extracellular space (GO:0005615) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

CCSB

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0

Q18501

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0

Q9U2Z5

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0

G5ECK4

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular (GO:0005622) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0

P34300

(UniProtKB/Swiss-Prot/P) Details

Fungus-induced protein 3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

CCSB

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0

Q8I4G9

(UniProtKB/TrEmbl/P) Details

DAB (Drosophila disabled) homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

CCSB

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0

Q8I4H0

(UniProtKB/TrEmbl/P) Details

DAB (Drosophila disabled) homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

CCSB

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0

Q9U3A6

(UniProtKB/TrEmbl/P) Details

DAB (Drosophila disabled) homolog

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

CCSB

Interaction Source Publication:

PubMed 

Q9BIF4

Interaction Score
0

W6RS10

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular (GO:0005622) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015