A0A087WZU5

Tetraspanin-6 // UniProt Profile

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Species	H. sapiens
Number of Interactions	26 / 30
Average Interaction Score	0.314

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

A0A087WZU5

Interaction Score

0.8

O95786

(UniProtKB/Swiss-Prot/P) Details

Probable ATP-dependent RNA helicase DDX58

A0A087WZU5

Interaction Score

0.799

Q12873

(UniProtKB/Swiss-Prot/P) Details

Chromodomain-helicase-DNA-binding protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	NuRD complex (GO:0016581)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	0.998	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A087WZU5

Interaction Score

0.796

Q9Y328

(UniProtKB/Swiss-Prot/P) Details

Neuronal vesicle trafficking-associated protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.994	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Trans-Golgi network membrane (GO:0032588)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Multivesicular body membrane (GO:0032585)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Vacuole (GO:0005773)	0.994	Experimental: experimental	eSLDB	PubMed
Cytosol	Lysosomal lumen (GO:0043202)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.982	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.982	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.982	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Vesicle (GO:0031982)	0.994	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A087WZU5

Interaction Score

0.768

Q9NY25

(UniProtKB/Swiss-Prot/P) Details

C-type lectin domain family 5 member A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Tertiary granule membrane (GO:0070821)	0.3	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A087WZU5

Interaction Score

0.768

Q5T3J3

(UniProtKB/Swiss-Prot/P) Details

Ligand-dependent nuclear receptor-interacting factor 1

A0A087WZU5

Interaction Score

0.768

Q7Z434

(UniProtKB/Swiss-Prot/P) Details

Mitochondrial antiviral-signaling protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: experimental	Human Proteinpedia	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial membrane (GO:0031966)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Peroxisomal membrane (GO:0005778)	0.96	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.86	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.86	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A087WZU5

Interaction Score

0.75

Q9BYX4

(UniProtKB/Swiss-Prot/P) Details

Interferon-induced helicase C domain-containing protein 1

A0A087WZU5

Interaction Score

0.64

Q92903

(UniProtKB/Swiss-Prot/P) Details

Phosphatidate cytidylyltransferase 1

A0A087WZU5

Interaction Score

0.64

Q14DL9

(UniProtKB/TrEmbl/P) Details

CLEC5A protein

A0A087WZU5

Interaction Score

0.632

Q86WV6

(UniProtKB/Swiss-Prot/P) Details

Stimulator of interferon genes protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.79	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.931	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Peroxisome (GO:0005777)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	0.931	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Secretory granule membrane (GO:0030667)	0.931	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.853	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.853	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A087WZU5

Interaction Score

0.56

O95498

(UniProtKB/Swiss-Prot/P) Details

Vascular non-inflammatory molecule 2

A0A087WZU5

Interaction Score

0.24

Q02223

(UniProtKB/Swiss-Prot/P) Details

Tumor necrosis factor receptor superfamily member 17

A0A087WZU5

Interaction Score

B7Z4G6

(UniProtKB/TrEmbl/P) Details

Transmembrane protein 185A

A0A087WZU5

Interaction Score

A0A024RDG8

(UniProtKB/TrEmbl/P) Details

Phosphatidate cytidylyltransferase

A0A087WZU5

Interaction Score

Q86UE6

(UniProtKB/Swiss-Prot/P) Details

Leucine-rich repeat transmembrane neuronal protein 1

A0A087WZU5

Interaction Score

Q3MIR4

(UniProtKB/Swiss-Prot/P) Details

Cell cycle control protein 50B

A0A087WZU5

Interaction Score

Q6UWN0

(UniProtKB/Swiss-Prot/P) Details

Ly6/PLAUR domain-containing protein 4

A0A087WZU5

Interaction Score

Q7Z602

(UniProtKB/Swiss-Prot/P) Details

Probable G-protein coupled receptor 141

A0A087WZU5

Interaction Score

Q8IW75

(UniProtKB/Swiss-Prot/P) Details

Serpin A12

A0A087WZU5

Interaction Score

Q96FT7

(UniProtKB/Swiss-Prot/P) Details

Acid-sensing ion channel 4

A0A087WZU5

Interaction Score

Q2TAZ1

(UniProtKB/TrEmbl/P) Details

CHD3 protein

A0A087WZU5

Interaction Score

A4D1U7

(UniProtKB/TrEmbl/P) Details

C-type (Calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5

A0A087WZU5

Interaction Score

P58658

(UniProtKB/Swiss-Prot/P) Details

Protein eva-1 homolog C

A0A087WZU5

Interaction Score

Q8TCB3

(UniProtKB/TrEmbl/P) Details

TMEM185A protein

A0A087WZU5

Interaction Score

Q8NFB2

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 185A

A0A087WZU5

Interaction Score

E7EMM1

(UniProtKB/TrEmbl/P) Details

Transmembrane protein 185A

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A0A087WZU5

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

A0A087WZU5

O95786

Probable ATP-dependent RNA helicase DDX58

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A087WZU5

Q12873

Chromodomain-helicase-DNA-binding protein 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A087WZU5

Q9Y328

Neuronal vesicle trafficking-associated protein 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A087WZU5

Q9NY25

C-type lectin domain family 5 member A

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A087WZU5

Q5T3J3

Ligand-dependent nuclear receptor-interacting factor 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A087WZU5

Q7Z434

Mitochondrial antiviral-signaling protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A087WZU5

Q9BYX4

Interferon-induced helicase C domain-containing protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A087WZU5

Q92903

Phosphatidate cytidylyltransferase 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A087WZU5

Q14DL9

CLEC5A protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A087WZU5

Q86WV6

Stimulator of interferon genes protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A087WZU5

O95498

Vascular non-inflammatory molecule 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A087WZU5

Q02223

Tumor necrosis factor receptor superfamily member 17

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A087WZU5