A0A0S2Z310

Serine/threonine-protein kinase receptor // UniProt Profile

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Species	H. sapiens
Number of Interactions	29 / 39
Average Interaction Score	0.381

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

A0A0S2Z310

Interaction Score

0.8

P01137

(UniProtKB/Swiss-Prot/P) Details

Transforming growth factor beta-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.853	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Cell surface (GO:0009986)	0.996	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.98	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.98	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.98	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Golgi lumen (GO:0005796)	0.853	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Platelet alpha granule lumen (GO:0031093)	0.853	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.98	Experimental: experimental	Human Proteinpedia	PubMed
Membrane	Microvillus (GO:0005902)	0.996	Experimental: inferred from direct assay	GO	PubMed
Membrane	Axon (GO:0030424)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.999	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.999	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.999	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Blood microparticle (GO:0072562)	0.999	Unknown: HDA	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.999	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.996	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A0S2Z310

Interaction Score

0.798

P08476

(UniProtKB/Swiss-Prot/P) Details

Inhibin beta A chain

A0A0S2Z310

Interaction Score

0.793

P17813

(UniProtKB/Swiss-Prot/P) Details

Endoglin

A0A0S2Z310

Interaction Score

0.766

Q8N6C5

(UniProtKB/Swiss-Prot/P) Details

Immunoglobulin superfamily member 1

A0A0S2Z310

Interaction Score

0.688

P07900

(UniProtKB/Swiss-Prot/P) Details

Heat shock protein HSP 90-alpha

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.987	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.987	Unknown: traceable author statement	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.987	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosomal lumen (GO:0043202)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endocytic vesicle lumen (GO:0071682)	0.657	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Melanosome (GO:0042470)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.657	Unknown: traceable author statement	GO	PubMed
Membrane	Dendritic growth cone (GO:0044294)	0.996	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Ruffle membrane (GO:0032587)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axonal growth cone (GO:0044295)	0.996	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.996	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.996	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A0S2Z310

Interaction Score

0.64

Q6NUK1

(UniProtKB/Swiss-Prot/P) Details

Calcium-binding mitochondrial carrier protein SCaMC-1

A0A0S2Z310

Interaction Score

0.64

P62942

(UniProtKB/Swiss-Prot/P) Details

Peptidyl-prolyl cis-trans isomerase FKBP1A

A0A0S2Z310

Interaction Score

0.64

Q13145

(UniProtKB/Swiss-Prot/P) Details

BMP and activin membrane-bound inhibitor homolog

A0A0S2Z310

Interaction Score

0.64

B4DXN7

(UniProtKB/TrEmbl/P) Details

Receptor protein serine/threonine kinase

A0A0S2Z310

Interaction Score

0.64

B4DY26

(UniProtKB/TrEmbl/P) Details

Receptor protein serine/threonine kinase

A0A0S2Z310

Interaction Score

0.64

P36897

(UniProtKB/Swiss-Prot/P) Details

TGF-beta receptor type-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane raft (GO:0045121)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Transforming growth factor beta receptor complex (GO:0070022)	1	Unknown: inferred by curator	GO	PubMed
Membrane	Tight junction (GO:0005923)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A0S2Z310

Interaction Score

0.64

Q5T7S2

(UniProtKB/TrEmbl/P) Details

Receptor protein serine/threonine kinase

A0A0S2Z310

Interaction Score

0.64

D3DPA4

(UniProtKB/TrEmbl/P) Details

Serine/threonine-protein kinase receptor

A0A0S2Z310

Interaction Score

0.64

Q04771

(UniProtKB/Swiss-Prot/P) Details

Activin receptor type-1

A0A0S2Z310

Interaction Score

0.64

Q9UNH7

(UniProtKB/Swiss-Prot/P) Details

Sorting nexin-6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Retromer complex (GO:0030904)	0.997	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Retromer complex, outer shell (GO:0030905)	0.997	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Intracellular (GO:0005622)	0.997	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Extrinsic to membrane (GO:0019898)	0.7	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A0S2Z310

Interaction Score

0.56

A4D1W7

(UniProtKB/TrEmbl/P) Details

Inhibin, beta A (Activin A, activin AB alpha polypeptide), isoform CRA_a

A0A0S2Z310

Interaction Score

0.24

P67870

(UniProtKB/Swiss-Prot/P) Details

Casein kinase II subunit beta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Unknown: traceable author statement	GO	PubMed
Cytosol	Protein kinase CK2 complex (GO:0005956)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.986	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear matrix (GO:0016363)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.986	Unknown: traceable author statement	GO	PubMed
Nucleus	PcG protein complex (GO:0031519)	0.986	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.79	Unknown: traceable author statement	GO	PubMed
Nucleus	Chromatin (GO:0000785)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cilium (GO:0005929)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.972	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.998	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A0S2Z310

Interaction Score

Q15797

(UniProtKB/Swiss-Prot/P) Details

Mothers against decapentaplegic homolog 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	0.996	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	SMAD protein complex (GO:0071141)	0.996	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear inner membrane (GO:0005637)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Transcription factor complex (GO:0005667)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.86	Unknown: non-traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.86	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A0A0S2Z310

Interaction Score

Q0VDC6

(UniProtKB/TrEmbl/P) Details

Peptidylprolyl isomerase

A0A0S2Z310

Interaction Score

B4DSP0

(UniProtKB/TrEmbl/P) Details

HCG1642748, isoform CRA_b

A0A0S2Z310

Interaction Score

P55055

(UniProtKB/Swiss-Prot/P) Details

Oxysterols receptor LXR-beta

A0A0S2Z310

Interaction Score

Q86TG7

(UniProtKB/Swiss-Prot/P) Details

Retrotransposon-derived protein PEG10

A0A0S2Z310

Interaction Score

A0A0A0MRI2

(UniProtKB/TrEmbl/P) Details

Sorting nexin

A0A0S2Z310

Interaction Score

A0A087X0H8

(UniProtKB/TrEmbl/P) Details

TSC22 domain family protein 1

A0A0S2Z310

Interaction Score

Q15714

(UniProtKB/Swiss-Prot/P) Details

TSC22 domain family protein 1

A0A0S2Z310

Interaction Score

Q14568

(UniProtKB/Swiss-Prot/P) Details

Heat shock protein HSP 90-alpha A2

A0A0S2Z310

Interaction Score

Q86SX1

(UniProtKB/TrEmbl/P) Details

Full-length cDNA 5-PRIME end of clone CS0DN005YI08 of Adult brain of Homo sapiens

A0A0S2Z310

Interaction Score

Q5T9B9

(UniProtKB/TrEmbl/P) Details

Endoglin (Osler-Rendu-Weber syndrome 1), isoform CRA_b

A0A0S2Z310

Interaction Score

Q96CG0

(UniProtKB/TrEmbl/P) Details

ENG protein

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A0A0S2Z310

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

A0A0S2Z310

P01137

Transforming growth factor beta-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A0S2Z310

P08476

Inhibin beta A chain

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A0S2Z310

P17813

Endoglin

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A0S2Z310

Q8N6C5

Immunoglobulin superfamily member 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A0S2Z310

P07900

Heat shock protein HSP 90-alpha

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A0S2Z310

Q6NUK1

Calcium-binding mitochondrial carrier protein SCaMC-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A0S2Z310

P62942

Peptidyl-prolyl cis-trans isomerase FKBP1A

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A0S2Z310

Q13145

BMP and activin membrane-bound inhibitor homolog

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A0S2Z310

B4DXN7

Receptor protein serine/threonine kinase

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A0S2Z310

B4DY26

Receptor protein serine/threonine kinase

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A0S2Z310

P36897

TGF-beta receptor type-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A0S2Z310

Q5T7S2

Receptor protein serine/threonine kinase

Localizations:

Interaction Source Database:

Interaction Source Publication:

A0A0S2Z310