A5X5Y0

5-hydroxytryptamine receptor 3E // UniProt Profile

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Species	H. sapiens
Number of Interactions	9 / 10
Average Interaction Score	0.657

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.987	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.987	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.987	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.987	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

A5X5Y0

Interaction Score

0.992

Q93084

(UniProtKB/Swiss-Prot/P) Details

Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Sarcoplasmic reticulum (GO:0016529)	0.902	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Sarcoplasmic reticulum membrane (GO:0033017)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Platelet dense tubular network membrane (GO:0031095)	0.902	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.992	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.992	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.992	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.992	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.992	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	0.992	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A5X5Y0

Interaction Score

0.978

Q9UKV5

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase AMFR

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.992	Experimental: experimental	Organelle	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.86	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Integral to endoplasmic reticulum membrane (GO:0030176)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum quality control compartment (GO:0044322)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Growth cone (GO:0030426)	0.952	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.952	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.952	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.952	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.952	Unknown: non-traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A5X5Y0

Interaction Score

0.971

O75915

(UniProtKB/Swiss-Prot/P) Details

PRA1 family protein 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.972	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.972	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.972	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.931	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.931	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.931	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A5X5Y0

Interaction Score

0.943

Q16850

(UniProtKB/Swiss-Prot/P) Details

Lanosterol 14-alpha demethylase

A5X5Y0

Interaction Score

0.747

Q9Y394

(UniProtKB/Swiss-Prot/P) Details

Dehydrogenase/reductase SDR family member 7

A5X5Y0

Interaction Score

0.64

A8K9K1

(UniProtKB/TrEmbl/P) Details

Calcium-transporting ATPase

A5X5Y0

Interaction Score

0.64

A0A024R371

(UniProtKB/TrEmbl/P) Details

PRA1 family protein

A5X5Y0

Interaction Score

Q7L5D6

(UniProtKB/Swiss-Prot/P) Details

Golgi to ER traffic protein 4 homolog

A5X5Y0

Interaction Score

A0A0C4DFL7

(UniProtKB/TrEmbl/P) Details

Lanosterol 14-alpha demethylase

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A5X5Y0

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

A5X5Y0

Q93084

Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

A5X5Y0

Q9UKV5

E3 ubiquitin-protein ligase AMFR

Localizations:

Interaction Source Database:

Interaction Source Publication:

A5X5Y0

O75915

PRA1 family protein 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

A5X5Y0

Q16850

Lanosterol 14-alpha demethylase

Localizations:

Interaction Source Database:

Interaction Source Publication:

A5X5Y0

Q9Y394

Dehydrogenase/reductase SDR family member 7

Localizations:

Interaction Source Database:

Interaction Source Publication:

A5X5Y0

A8K9K1

Calcium-transporting ATPase

Localizations:

Interaction Source Database:

Interaction Source Publication:

A5X5Y0

A0A024R371

PRA1 family protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

A5X5Y0

Q7L5D6

Golgi to ER traffic protein 4 homolog

Localizations:

Interaction Source Database:

Interaction Source Publication:

A5X5Y0

A0A0C4DFL7

Lanosterol 14-alpha demethylase

Localizations:

Interaction Source Database:

Interaction Source Publication: