A6NFQ2

TRPM8 channel-associated factor 2 // UniProt Profile

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Species	H. sapiens
Number of Interactions	26 / 37
Average Interaction Score	0.931

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Lysosome (GO:0005764)	0.91	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

A6NFQ2

Interaction Score

Q9NZU1

(UniProtKB/Swiss-Prot/P) Details

Leucine-rich repeat transmembrane protein FLRT1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body membrane (GO:0032809)	0.973	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.973	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.973	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.853	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuron projection terminus (GO:0044306)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.994	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.994	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.994	Unknown: non-traceable author statement	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.994	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Cell-cell junction (GO:0005911)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A6NFQ2

Interaction Score

Q6UXF1

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 108

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	Cellular component (GO:0005575)	0.3	Unknown: no biological data available	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.91	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.91	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Axon (GO:0030424)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	0.999	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A6NFQ2

Interaction Score

P16070

(UniProtKB/Swiss-Prot/P) Details

CD44 antigen

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Macrophage migration inhibitory factor receptor complex (GO:0035692)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.86	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.992	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Secretory granule membrane (GO:0030667)	0.992	Unknown: traceable author statement	GO	PubMed
Membrane	Cell projection (GO:0042995)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Microvillus (GO:0005902)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Lamellipodium membrane (GO:0031258)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.86	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A6NFQ2

Interaction Score

Q8IUW5

(UniProtKB/Swiss-Prot/P) Details

RELT-like protein 1

A6NFQ2

Interaction Score

0.999

Q9NZ94

(UniProtKB/Swiss-Prot/P) Details

Neuroligin-3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endocytic vesicle (GO:0030139)	0.94	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Synapse (GO:0045202)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Excitatory synapse (GO:0060076)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

A6NFQ2

Interaction Score

0.999

P26842

(UniProtKB/Swiss-Prot/P) Details

CD27 antigen

A6NFQ2

Interaction Score

0.999

Q15768

(UniProtKB/Swiss-Prot/P) Details

Ephrin-B3

A6NFQ2

Interaction Score

0.999

Q16581

(UniProtKB/Swiss-Prot/P) Details

C3a anaphylatoxin chemotactic receptor

A6NFQ2

Interaction Score

0.995

Q8IYJ0

(UniProtKB/Swiss-Prot/P) Details

PILR alpha-associated neural protein

A6NFQ2

Interaction Score

0.995

Q8TDQ0

(UniProtKB/Swiss-Prot/P) Details

Hepatitis A virus cellular receptor 2

A6NFQ2

Interaction Score

0.992

P02724

(UniProtKB/Swiss-Prot/P) Details

Glycophorin-A

A6NFQ2

Interaction Score

0.99

Q9H8J5

(UniProtKB/Swiss-Prot/P) Details

MANSC domain-containing protein 1

A6NFQ2

Interaction Score

0.985

Q9NQX5

(UniProtKB/Swiss-Prot/P) Details

Neural proliferation differentiation and control protein 1

A6NFQ2

Interaction Score

0.982

Q9Y279

(UniProtKB/Swiss-Prot/P) Details

V-set and immunoglobulin domain-containing protein 4

A6NFQ2

Interaction Score

0.978

P80370

(UniProtKB/Swiss-Prot/P) Details

Protein delta homolog 1

A6NFQ2

Interaction Score

0.975

B3KT64

(UniProtKB/TrEmbl/P) Details

cDNA FLJ37731 fis, clone BRHIP2020743, moderately similar to Transmembrane protein 108

A6NFQ2

Interaction Score

0.964

P06028

(UniProtKB/Swiss-Prot/P) Details

Glycophorin-B

A6NFQ2

Interaction Score

0.959

P24592

(UniProtKB/Swiss-Prot/P) Details

Insulin-like growth factor-binding protein 6

A6NFQ2

Interaction Score

0.928

Q7Z5A8

(UniProtKB/Swiss-Prot/P) Details

Protein FAM19A3

A6NFQ2

Interaction Score

0.915

Q13477

(UniProtKB/Swiss-Prot/P) Details

Mucosal addressin cell adhesion molecule 1

A6NFQ2

Interaction Score

0.892

A0A0C4DFT7

(UniProtKB/TrEmbl/P) Details

Glycophorin

A6NFQ2

Interaction Score

0.891

Q6MZK0

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686F02202

A6NFQ2

Interaction Score

0.847

Q17RF5

(UniProtKB/Swiss-Prot/P) Details

Odontogenesis associated phosphoprotein

A6NFQ2

Interaction Score

0.64

Q14419

(UniProtKB/TrEmbl/P) Details

Glycophorin

A6NFQ2

Interaction Score

0.64

E9PD10

(UniProtKB/TrEmbl/P) Details

Glycophorin

A6NFQ2

Interaction Score

0.637

Q4G160

(UniProtKB/TrEmbl/P) Details

NLGN3 protein

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A6NFQ2

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

A6NFQ2

Q9NZU1

Leucine-rich repeat transmembrane protein FLRT1

Localizations:

Interaction Source Database:

Interaction Source Publication:

A6NFQ2

Q6UXF1

Transmembrane protein 108

Localizations:

Interaction Source Database:

Interaction Source Publication:

A6NFQ2

P16070

CD44 antigen

Localizations:

Interaction Source Database:

Interaction Source Publication:

A6NFQ2

Q8IUW5

RELT-like protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

A6NFQ2

Q9NZ94

Neuroligin-3

Localizations:

Interaction Source Database:

Interaction Source Publication:

A6NFQ2

P26842

CD27 antigen

Localizations:

Interaction Source Database:

Interaction Source Publication:

A6NFQ2

Q15768

Ephrin-B3

Localizations:

Interaction Source Database:

Interaction Source Publication:

A6NFQ2

Q16581

C3a anaphylatoxin chemotactic receptor

Localizations:

Interaction Source Database:

Interaction Source Publication:

A6NFQ2

Q8IYJ0

PILR alpha-associated neural protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

A6NFQ2

Q8TDQ0

Hepatitis A virus cellular receptor 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

A6NFQ2

P02724

Glycophorin-A

Localizations:

Interaction Source Database:

Interaction Source Publication:

A6NFQ2

Q9H8J5

MANSC domain-containing protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

A6NFQ2