H7BXI1

Extended synaptotagmin-2 // UniProt Profile

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Species	H. sapiens
Number of Interactions	9 / 9
Average Interaction Score	0.561

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.79	Unknown: unspecified method	The Human Protein Atlas	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

H7BXI1

Interaction Score

0.789

Q9BQE3

(UniProtKB/Swiss-Prot/P) Details

Tubulin alpha-1C chain

H7BXI1

Interaction Score

0.789

P98174

(UniProtKB/Swiss-Prot/P) Details

FYVE, RhoGEF and PH domain-containing protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Ruffle (GO:0001726)	0.996	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	0.996	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Membrane (GO:0016020)	0.996	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

H7BXI1

Interaction Score

0.788

Q99549

(UniProtKB/Swiss-Prot/P) Details

M-phase phosphoprotein 8

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ubiquitin ligase complex (GO:0000151)	0.998	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear heterochromatin (GO:0005720)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear nucleosome (GO:0000788)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

H7BXI1

Interaction Score

0.788

O00567

(UniProtKB/Swiss-Prot/P) Details

Nucleolar protein 56

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Pre-snoRNP complex (GO:0070761)	0.997	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Small nucleolar ribonucleoprotein complex (GO:0005732)	0.997	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Box C/D snoRNP complex (GO:0031428)	0.997	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Small-subunit processome (GO:0032040)	0.997	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

H7BXI1

Interaction Score

0.784

Q8IWL3

(UniProtKB/Swiss-Prot/P) Details

Iron-sulfur cluster co-chaperone protein HscB, mitochondrial

H7BXI1

Interaction Score

0.713

Q92542

(UniProtKB/Swiss-Prot/P) Details

Nicastrin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.902	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.999	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	0.902	Unknown: HDA	GO	PubMed
Secretory-pathway	Melanosome (GO:0042470)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.999	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Unknown: non-traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: experimental	Organelle	PubMed
Membrane	Gamma-secretase complex (GO:0070765)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.902	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

H7BXI1

Interaction Score

0.403

O75787

(UniProtKB/Swiss-Prot/P) Details

Renin receptor

H7BXI1

Interaction Score

P09466

(UniProtKB/Swiss-Prot/P) Details

Glycodelin

H7BXI1

Interaction Score

O00472

(UniProtKB/Swiss-Prot/P) Details

RNA polymerase II elongation factor ELL2

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H7BXI1

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

H7BXI1

Q9BQE3

Tubulin alpha-1C chain

Localizations:

Interaction Source Database:

Interaction Source Publication:

H7BXI1

P98174

FYVE, RhoGEF and PH domain-containing protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

H7BXI1

Q99549

M-phase phosphoprotein 8

Localizations:

Interaction Source Database:

Interaction Source Publication:

H7BXI1

O00567

Nucleolar protein 56

Localizations:

Interaction Source Database:

Interaction Source Publication:

H7BXI1

Q8IWL3

Iron-sulfur cluster co-chaperone protein HscB, mitochondrial

Localizations:

Interaction Source Database:

Interaction Source Publication:

H7BXI1

Q92542

Nicastrin

Localizations:

Interaction Source Database:

Interaction Source Publication:

H7BXI1

O75787

Renin receptor

Localizations:

Interaction Source Database:

Interaction Source Publication:

H7BXI1

P09466

Glycodelin

Localizations:

Interaction Source Database:

Interaction Source Publication:

H7BXI1

O00472

RNA polymerase II elongation factor ELL2

Localizations:

Interaction Source Database:

Interaction Source Publication: