H7BY84

General transcription factor 3C polypeptide 5 // UniProt Profile

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Species	H. sapiens
Number of Interactions	58 / 77
Average Interaction Score	0.789

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.94	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

H7BY84

Interaction Score

0.94

P20226

(UniProtKB/Swiss-Prot/P) Details

TATA-box-binding protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	Transcriptional preinitiation complex (GO:0097550)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Female pronucleus (GO:0001939)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Male pronucleus (GO:0001940)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcription factor TFIIA complex (GO:0005672)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Transcription factor TFIID complex (GO:0005669)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear euchromatin (GO:0005719)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

H7BY84

Interaction Score

0.94

O14980

(UniProtKB/Swiss-Prot/P) Details

Exportin-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear envelope (GO:0005635)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Cajal body (GO:0015030)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Kinetochore (GO:0000776)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Extracellular	Host cell (GO:0043657)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed
Secretory-pathway	Annulate lamellae (GO:0005642)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

H7BY84

Interaction Score

0.94

Q12962

(UniProtKB/Swiss-Prot/P) Details

Transcription initiation factor TFIID subunit 10

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcription factor TFIID complex (GO:0005669)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Transcription factor TFTC complex (GO:0033276)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	STAGA complex (GO:0030914)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	PCAF complex (GO:0000125)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

H7BY84

Interaction Score

0.94

Q06330

(UniProtKB/Swiss-Prot/P) Details

Recombining binding protein suppressor of hairless

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	MAML1-RBP-Jkappa- ICN1 complex (GO:0002193)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcriptional repressor complex (GO:0017053)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Transcription factor complex (GO:0005667)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

H7BY84

Interaction Score

0.94

Q9Y5Q9

(UniProtKB/Swiss-Prot/P) Details

General transcription factor 3C polypeptide 3

H7BY84

Interaction Score

0.94

P22087

(UniProtKB/Swiss-Prot/P) Details

rRNA 2'-O-methyltransferase fibrillarin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Box C/D snoRNP complex (GO:0031428)	0.937	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Small-subunit processome (GO:0032040)	0.937	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Granular component (GO:0001652)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Dense fibrillar component (GO:0001651)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Cajal body (GO:0015030)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.937	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

H7BY84

Interaction Score

0.94

Q9H4L7

(UniProtKB/Swiss-Prot/P) Details

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

H7BY84

Interaction Score

0.94

Q12789

(UniProtKB/Swiss-Prot/P) Details

General transcription factor 3C polypeptide 1

H7BY84

Interaction Score

0.94

Q09472

(UniProtKB/Swiss-Prot/P) Details

Histone acetyltransferase p300

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Transcription factor complex (GO:0005667)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Histone acetyltransferase complex (GO:0000123)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Protein-DNA complex (GO:0032993)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

H7BY84

Interaction Score

0.94

Q86U86

(UniProtKB/Swiss-Prot/P) Details

Protein polybromo-1

H7BY84

Interaction Score

0.94

Q6ZW49

(UniProtKB/Swiss-Prot/P) Details

PAX-interacting protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear matrix (GO:0016363)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Histone methyltransferase complex (GO:0035097)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	MLL3/4 complex (GO:0044666)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

H7BY84

Interaction Score

0.94

Q9NPI1

(UniProtKB/Swiss-Prot/P) Details

Bromodomain-containing protein 7

H7BY84

Interaction Score

0.94

P15884

(UniProtKB/Swiss-Prot/P) Details

Transcription factor 4

H7BY84

Interaction Score

0.94

Q13469

(UniProtKB/Swiss-Prot/P) Details

Nuclear factor of activated T-cells, cytoplasmic 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear transcription factor complex (GO:0044798)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

H7BY84

Interaction Score

0.94

P55072

(UniProtKB/Swiss-Prot/P) Details

Transitional endoplasmic reticulum ATPase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Lipid particle (GO:0005811)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasmic stress granule (GO:0010494)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Proteasome complex (GO:0000502)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Cdc48p-Npl4p-Ufd1p AAA ATPase complex (GO:0034098)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.994	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Azurophil granule lumen (GO:0035578)	0.994	Unknown: traceable author statement	GO	PubMed
Nucleus	Site of double-strand break (GO:0035861)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

H7BY84

Interaction Score

0.94

Q969F1

(UniProtKB/Swiss-Prot/P) Details

General transcription factor 3C polypeptide 6

H7BY84

Interaction Score

0.94

Q8WUA4

(UniProtKB/Swiss-Prot/P) Details

General transcription factor 3C polypeptide 2

H7BY84

Interaction Score

0.94

Q92994

(UniProtKB/Swiss-Prot/P) Details

Transcription factor IIIB 90 kDa subunit

H7BY84

Interaction Score

0.94

Q14258

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin/ISG15 ligase TRIM25

H7BY84

Interaction Score

0.94

Q9UBN7

(UniProtKB/Swiss-Prot/P) Details

Histone deacetylase 6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell leading edge (GO:0031252)	0.996	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perikaryon (GO:0043204)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Inclusion body (GO:0016234)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Aggresome (GO:0016235)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Histone deacetylase complex (GO:0000118)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Multivesicular body (GO:0005771)	0.3	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Microtubule associated complex (GO:0005875)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Dynein complex (GO:0030286)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasmic microtubule (GO:0005881)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.996	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Axon (GO:0030424)	0.996	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Caveola (GO:0005901)	0.996	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

H7BY84

Interaction Score

0.94

Q9BUI4

(UniProtKB/Swiss-Prot/P) Details

DNA-directed RNA polymerase III subunit RPC3

H7BY84

Interaction Score

0.94

P53350

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase PLK1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle (GO:0005819)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle midzone (GO:0051233)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle microtubule (GO:0005876)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle pole (GO:0000922)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Centriolar satellite (GO:0034451)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Centriole (GO:0005814)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Condensed nuclear chromosome outer kinetochore (GO:0000942)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Synaptonemal complex (GO:0000795)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromatin (GO:0000785)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Kinetochore (GO:0000776)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

H7BY84

Interaction Score

0.94

O43638

(UniProtKB/Swiss-Prot/P) Details

Forkhead box protein S1

H7BY84

Interaction Score

0.94

Q9UKN8

(UniProtKB/Swiss-Prot/P) Details

General transcription factor 3C polypeptide 4

H7BY84

Interaction Score

0.94

Q9HD15

(UniProtKB/Swiss-Prot/P) Details

Steroid receptor RNA activator 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Intercellular bridge (GO:0045171)	0.8	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

H7BY84

Interaction Score

0.94

Q9UJW3

(UniProtKB/Swiss-Prot/P) Details

DNA (cytosine-5)-methyltransferase 3-like

H7BY84

Interaction Score

0.938

Q9BV73

(UniProtKB/Swiss-Prot/P) Details

Centrosome-associated protein CEP250

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	Organelle	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.998	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centriole (GO:0005814)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	0.998	Experimental: experimental	Organelle	PubMed
Membrane	Cilium (GO:0005929)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

H7BY84

Interaction Score

0.938

Q9C009

(UniProtKB/Swiss-Prot/P) Details

Forkhead box protein Q1

H7BY84

Interaction Score

0.938

Q99853

(UniProtKB/Swiss-Prot/P) Details

Forkhead box protein B1

H7BY84

Interaction Score

0.938

P15036

(UniProtKB/Swiss-Prot/P) Details

Protein C-ets-2

H7BY84

Interaction Score

0.937

Q12952

(UniProtKB/Swiss-Prot/P) Details

Forkhead box protein L1

H7BY84

Interaction Score

0.937

Q9H0W5

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil domain-containing protein 8

H7BY84

Interaction Score

0.937

Q9H8V3

(UniProtKB/Swiss-Prot/P) Details

Protein ECT2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cleavage furrow (GO:0032154)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centralspindlin complex (GO:0097149)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Mitotic spindle (GO:0072686)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell-cell junction (GO:0005911)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Tight junction (GO:0005923)	0.992	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

H7BY84

Interaction Score

0.932

P55316

(UniProtKB/Swiss-Prot/P) Details

Forkhead box protein G1

H7BY84

Interaction Score

0.929

O43680

(UniProtKB/Swiss-Prot/P) Details

Transcription factor 21

H7BY84

Interaction Score

0.923

Q9H9E1

(UniProtKB/Swiss-Prot/P) Details

Ankyrin repeat family A protein 2

H7BY84

Interaction Score

0.914

Q13616

(UniProtKB/Swiss-Prot/P) Details

Cullin-1

H7BY84

Interaction Score

0.884

Q32MN7

(UniProtKB/TrEmbl/P) Details

TATA box binding protein, isoform CRA_a

H7BY84

Interaction Score

0.884

Q99750

(UniProtKB/Swiss-Prot/P) Details

MyoD family inhibitor

H7BY84

Interaction Score

0.884

Q9BRX7

(UniProtKB/TrEmbl/P) Details

HDAC6 protein

H7BY84

Interaction Score

0.881

Q13618

(UniProtKB/Swiss-Prot/P) Details

Cullin-3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cul3-RING ubiquitin ligase complex (GO:0031463)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.937	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.937	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.86	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Polar microtubule (GO:0005827)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Sperm flagellum (GO:0036126)	0.86	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

H7BY84

Interaction Score

0.855

Q7Z6C1

(UniProtKB/TrEmbl/P) Details

EP300 protein

H7BY84

Interaction Score

0.752

A0A1B0GVR6

(UniProtKB/TrEmbl/P) Details

Transcription factor 4

H7BY84

Interaction Score

0.752

H3BTP3

(UniProtKB/TrEmbl/P) Details

Transcription factor 4

H7BY84

Interaction Score

0.752

H3BPJ7

(UniProtKB/TrEmbl/P) Details

Transcription factor 4

H7BY84

Interaction Score

0.752

E9PH57

(UniProtKB/TrEmbl/P) Details

Transcription factor 4, isoform CRA_e

H7BY84

Interaction Score

0.752

Q498Y4

(UniProtKB/TrEmbl/P) Details

Forkhead box L1

H7BY84

Interaction Score

0.752

A0A1B0GW91

(UniProtKB/TrEmbl/P) Details

Transcription factor 4

H7BY84

Interaction Score

0.752

A0A1B0GWD5

(UniProtKB/TrEmbl/P) Details

Transcription factor 4

H7BY84

Interaction Score

0.752

B1AKB6

(UniProtKB/TrEmbl/P) Details

MyoD family inhibitor

H7BY84

Interaction Score

0.658

P04629

(UniProtKB/Swiss-Prot/P) Details

High affinity nerve growth factor receptor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.897	Unknown: unspecified method	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.897	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.994	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.994	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Late endosome membrane (GO:0031902)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Late endosome (GO:0005770)	0.994	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.897	Predicted: pTarget method	LOCATE	PubMed
Membrane	Dendrite (GO:0030425)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

H7BY84

Interaction Score

P60369

(UniProtKB/Swiss-Prot/P) Details

Keratin-associated protein 10-3

H7BY84

Interaction Score

Q6A162

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cytoskeletal 40

H7BY84

Interaction Score

Q9NSW6

(UniProtKB/TrEmbl/P) Details

Histone deacetylase

H7BY84

Interaction Score

Q9BPW8

(UniProtKB/Swiss-Prot/P) Details

Protein NipSnap homolog 1

H7BY84

Interaction Score

P15735

(UniProtKB/Swiss-Prot/P) Details

Phosphorylase b kinase gamma catalytic chain, liver/testis isoform

H7BY84

Interaction Score

X5DR71

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase receptor

H7BY84

Interaction Score

Q7Z3S9

(UniProtKB/Swiss-Prot/P) Details

Notch homolog 2 N-terminal-like protein

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H7BY84

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

H7BY84

P20226

TATA-box-binding protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

H7BY84

O14980

Exportin-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

H7BY84

Q12962

Transcription initiation factor TFIID subunit 10

Localizations:

Interaction Source Database:

Interaction Source Publication:

H7BY84

Q06330

Recombining binding protein suppressor of hairless

Localizations:

Interaction Source Database:

Interaction Source Publication:

H7BY84

Q9Y5Q9

General transcription factor 3C polypeptide 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

H7BY84

P22087

rRNA 2'-O-methyltransferase fibrillarin

Localizations:

Interaction Source Database:

Interaction Source Publication:

H7BY84

Q9H4L7

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

H7BY84

Q12789

General transcription factor 3C polypeptide 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

H7BY84

Q09472

Histone acetyltransferase p300

Localizations:

Interaction Source Database:

Interaction Source Publication:

H7BY84

Q86U86

Protein polybromo-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

H7BY84

Q6ZW49

PAX-interacting protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

H7BY84

Q9NPI1

Bromodomain-containing protein 7

Localizations:

Interaction Source Database:

Interaction Source Publication:

H7BY84