O00445

Synaptotagmin-5    //   UniProt Profile 

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Species

 H. sapiens

Number of Interactions

 8 / 12

Average Interaction Score

 0.768

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Neuronal cell body (GO:0043025) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.971 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endosome (GO:0005768) 0.958 Experimental: experimental eSLDB PubMed 
Secretory-pathway Recycling endosome membrane (GO:0055038) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Synaptic vesicle membrane (GO:0030672) 0.958 Predicted: inferred from biological aspect of ancestor GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.958 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Vesicle (GO:0031982) 0.971 Experimental: experimental eSLDB PubMed 
Membrane Cell junction (GO:0030054) 0.958 Unknown: inferred from electronic annotation GO PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

O00445

Interaction Score
1

P21579

(UniProtKB/Swiss-Prot/P) Details

Synaptotagmin-1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.988 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.988 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.992 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Chromaffin granule membrane (GO:0042584) 0.992 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Dense core granule (GO:0031045) 0.992 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Clathrin coated vesicle membrane (GO:0030665) 0.992 Unknown: traceable author statement GO PubMed 
Secretory-pathway Synaptic vesicle (GO:0008021) 0.992 Unknown: traceable author statement GO PubMed 
Secretory-pathway Synaptic vesicle membrane (GO:0030672) 0.992 Predicted: inferred from biological aspect of ancestor GO PubMed 
Secretory-pathway Integral to synaptic vesicle membrane (GO:0030285) 0.992 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Clathrin sculpted acetylcholine transport vesicle membrane (GO:0060201) 0.992 Unknown: traceable author statement GO PubMed 
Secretory-pathway Clathrin sculpted glutamate transport vesicle membrane (GO:0060203) 0.992 Unknown: traceable author statement GO PubMed 
Secretory-pathway Clathrin sculpted monoamine transport vesicle membrane (GO:0070083) 0.992 Unknown: traceable author statement GO PubMed 
Secretory-pathway Clathrin sculpted gamma-aminobutyric acid transport vesicle membrane (GO:0061202) 0.992 Unknown: traceable author statement GO PubMed 
Membrane Neuron projection (GO:0043005) 0.989 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Neuron projection terminus (GO:0044306) 0.989 Unknown: inferred from electronic annotation GO PubMed 
Membrane Axon (GO:0030424) 0.989 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane SNARE complex (GO:0031201) 0.989 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.989 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Vesicle (GO:0031982) 0.988 Experimental: experimental eSLDB PubMed 
Membrane Cell junction (GO:0030054) 0.989 Unknown: inferred from electronic annotation GO PubMed 
Membrane Excitatory synapse (GO:0060076) 0.989 Unknown: inferred from electronic annotation GO PubMed 
Membrane Presynaptic membrane (GO:0042734) 0.989 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O00445

Interaction Score
1

Q9BQG1

(UniProtKB/Swiss-Prot/P) Details

Synaptotagmin-3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endosome (GO:0005768) 0.972 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome (GO:0005768) 0.972 Experimental: experimental Human Proteinpedia PubMed 
Secretory-pathway Transport vesicle membrane (GO:0030658) 0.972 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.992 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.992 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.992 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.992 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Vesicle (GO:0031982) 0.94 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed 

O00445

Interaction Score
1

P62820

(UniProtKB/Swiss-Prot/P) Details

Ras-related protein Rab-1A

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.994 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.994 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytosol (GO:0005829) 0.994 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.994 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.999 Predicted: inferred from biological aspect of ancestor GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.999 Unknown: HDA GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.999 Predicted: inferred from biological aspect of ancestor GO PubMed 
Secretory-pathway Early endosome (GO:0005769) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Melanosome (GO:0042470) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Transport vesicle membrane (GO:0030658) 0.999 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.7 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.994 Unknown: HDA GO PubMed 

Interaction Source Database:

HPRD, IntAct

Interaction Source Publication:

PubMed 

O00445

Interaction Score
0.993

Q8IXS6

(UniProtKB/Swiss-Prot/P) Details

Paralemmin-2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.86 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.86 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O00445

Interaction Score
0.988

Q4FD32

(UniProtKB/TrEmbl/P) Details

Synaptotagmin V

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Endosome (GO:0005768) 0.8 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.8 Experimental: experimental eSLDB PubMed 
Cytosol Vesicle (GO:0031982) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O00445

Interaction Score
0.871

Q8NEY4

(UniProtKB/Swiss-Prot/P) Details

V-type proton ATPase subunit C 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.897 Unknown: traceable author statement GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.79 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.79 Unknown: unspecified method The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Vacuolar proton-transporting V-type ATPase, V1 domain (GO:0000221) 0.897 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Lysosomal membrane (GO:0005765) 0.897 Unknown: HDA GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.897 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O00445

Interaction Score
0.291

P19388

(UniProtKB/Swiss-Prot/P) Details

DNA-directed RNA polymerases I, II, and III subunit RPABC1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.3 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus DNA-directed RNA polymerase I complex (GO:0005736) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus DNA-directed RNA polymerase III complex (GO:0005666) 1 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus DNA-directed RNA polymerase II, core complex (GO:0005665) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus RNA polymerase complex (GO:0030880) 1 Experimental: experimental Organelle PubMed 

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed 

O00445

Interaction Score
0

A0A0U1RR16

(UniProtKB/TrEmbl/P) Details

V-type proton ATPase subunit C

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.3 Unknown: unspecified method The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015