O14732

Inositol monophosphatase 2 // UniProt Profile

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Species	H. sapiens
Number of Interactions	55 / 82
Average Interaction Score	0.843

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

O14732

Interaction Score

Q99497

(UniProtKB/Swiss-Prot/P) Details

Protein/nucleic acid deglycase DJ-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cell body (GO:0044297)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrial intermembrane space (GO:0005758)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrial respiratory chain complex I (GO:0005747)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	PML body (GO:0016605)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromatin (GO:0000785)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Axon (GO:0030424)	0.897	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane raft (GO:0045121)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell-cell adherens junction (GO:0005913)	0.897	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14732

Interaction Score

0.999

Q04760

(UniProtKB/Swiss-Prot/P) Details

Lactoylglutathione lyase

O14732

Interaction Score

0.999

P29218

(UniProtKB/Swiss-Prot/P) Details

Inositol monophosphatase 1

O14732

Interaction Score

0.999

P10599

(UniProtKB/Swiss-Prot/P) Details

Thioredoxin

O14732

Interaction Score

0.999

P14866

(UniProtKB/Swiss-Prot/P) Details

Heterogeneous nuclear ribonucleoprotein L

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Ribonucleoprotein granule (GO:0035770)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14732

Interaction Score

0.999

Q8TBC4

(UniProtKB/Swiss-Prot/P) Details

NEDD8-activating enzyme E1 catalytic subunit

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed

O14732

Interaction Score

0.999

P09972

(UniProtKB/Swiss-Prot/P) Details

Fructose-bisphosphate aldolase C

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Fibrillar center (GO:0001650)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.3	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Unknown: inferred by curator	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14732

Interaction Score

0.999

O95336

(UniProtKB/Swiss-Prot/P) Details

6-phosphogluconolactonase

O14732

Interaction Score

0.999

P04075

(UniProtKB/Swiss-Prot/P) Details

Fructose-bisphosphate aldolase A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: HDA	GO	PubMed
Secretory-pathway	Secretory granule lumen (GO:0034774)	0.51	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Platelet alpha granule lumen (GO:0031093)	0.51	Unknown: traceable author statement	GO	PubMed
Cytosol	I band (GO:0031674)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	M band (GO:0031430)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.902	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.902	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.902	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14732

Interaction Score

0.999

P16949

(UniProtKB/Swiss-Prot/P) Details

Stathmin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.79	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14732

Interaction Score

0.999

Q13310

(UniProtKB/Swiss-Prot/P) Details

Polyadenylate-binding protein 4

O14732

Interaction Score

0.999

O75340

(UniProtKB/Swiss-Prot/P) Details

Programmed cell death protein 6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cul3-RING ubiquitin ligase complex (GO:0031463)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum exit site (GO:0070971)	0.999	Experimental: inferred from mutant phenotype	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	COPII vesicle coat (GO:0030127)	0.999	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14732

Interaction Score

0.998

Q9Y2V2

(UniProtKB/Swiss-Prot/P) Details

Calcium-regulated heat-stable protein 1

O14732

Interaction Score

0.997

P26038

(UniProtKB/Swiss-Prot/P) Details

Moesin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Myelin sheath (GO:0043209)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Apical part of cell (GO:0045177)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Unknown: HDA	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: HDA	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Membrane	Cell periphery (GO:0071944)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Uropod (GO:0001931)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Pseudopodium (GO:0031143)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Microvillus (GO:0005902)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Microvillus membrane (GO:0031528)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Invadopodium (GO:0071437)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Filopodium (GO:0030175)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.902	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.902	Unknown: HDA	GO	PubMed
Extracellular	Blood microparticle (GO:0072562)	0.902	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Basolateral plasma membrane (GO:0016323)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Vesicle (GO:0031982)	1	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14732

Interaction Score

0.997

Q14258

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin/ISG15 ligase TRIM25

O14732

Interaction Score

0.996

Q16658

(UniProtKB/Swiss-Prot/P) Details

Fascin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Podosome (GO:0002102)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Filamentous actin (GO:0031941)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Stress fiber (GO:0001725)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Microspike (GO:0044393)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Growth cone (GO:0030426)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Ruffle (GO:0001726)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Microvillus (GO:0005902)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Invadopodium (GO:0071437)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Filopodium (GO:0030175)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell projection membrane (GO:0031253)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell-cell junction (GO:0005911)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14732

Interaction Score

0.996

P40227

(UniProtKB/Swiss-Prot/P) Details

T-complex protein 1 subunit zeta

O14732

Interaction Score

0.996

O60664

(UniProtKB/Swiss-Prot/P) Details

Perilipin-3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Lipid particle (GO:0005811)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lipid particle (GO:0005811)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.76	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.76	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.76	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Transport vesicle (GO:0030133)	0.76	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14732

Interaction Score

0.996

P22234

(UniProtKB/Swiss-Prot/P) Details

Multifunctional protein ADE2

O14732

Interaction Score

0.996

P30520

(UniProtKB/Swiss-Prot/P) Details

Adenylosuccinate synthetase isozyme 2

O14732

Interaction Score

0.996

Q9BY32

(UniProtKB/Swiss-Prot/P) Details

Inosine triphosphate pyrophosphatase

O14732

Interaction Score

0.995

P52565

(UniProtKB/Swiss-Prot/P) Details

Rho GDP-dissociation inhibitor 1

O14732

Interaction Score

0.995

P35241

(UniProtKB/Swiss-Prot/P) Details

Radixin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Myelin sheath (GO:0043209)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell tip (GO:0051286)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cleavage furrow (GO:0032154)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Stereocilium (GO:0032420)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Cortical actin cytoskeleton (GO:0030864)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Cell periphery (GO:0071944)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Ruffle (GO:0001726)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Microvillus (GO:0005902)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Filopodium (GO:0030175)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.86	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	T-tubule (GO:0030315)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Unknown: HDA	GO	PubMed
Membrane	Cell-cell adherens junction (GO:0005913)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14732

Interaction Score

0.993

P99999

(UniProtKB/Swiss-Prot/P) Details

Cytochrome c

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Protein phosphatase type 2A complex (GO:0000159)	0.86	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.86	Experimental: inferred from mutant phenotype	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial intermembrane space (GO:0005758)	0.999	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: experimental	Human Proteinpedia	PubMed
Membrane	Respiratory chain (GO:0070469)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14732

Interaction Score

0.991

Q15011

(UniProtKB/Swiss-Prot/P) Details

Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.972	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.972	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	0.972	Unknown: unspecified method	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.91	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.971	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.971	Experimental: experimental	eSLDB	PubMed
Membrane	Calcium channel complex (GO:0034704)	0.971	Predicted: inferred from physical interaction	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.971	Unknown: unspecified method	The Human Protein Atlas	PubMed

Interaction Source Database:

HPRD, IntAct

Interaction Source Publication:

PubMed

O14732

Interaction Score

0.991

Q03933

(UniProtKB/Swiss-Prot/P) Details

Heat shock factor protein 2

O14732

Interaction Score

0.991

Q9NWB1

(UniProtKB/Swiss-Prot/P) Details

RNA binding protein fox-1 homolog 1

O14732

Interaction Score

0.99

Q96AT9

(UniProtKB/Swiss-Prot/P) Details

Ribulose-phosphate 3-epimerase

O14732

Interaction Score

0.984

F8W8D4

(UniProtKB/TrEmbl/P) Details

NEDD8-activating enzyme E1 catalytic subunit

O14732

Interaction Score

0.98

P36969

(UniProtKB/Swiss-Prot/P) Details

Phospholipid hydroperoxide glutathione peroxidase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.51	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.998	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.998	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Unknown: HDA	GO	PubMed
Nucleus	Nuclear envelope (GO:0005635)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.996	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.996	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.51	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14732

Interaction Score

0.977

Q9Y312

(UniProtKB/Swiss-Prot/P) Details

Protein AAR2 homolog

O14732

Interaction Score

0.967

P33316

(UniProtKB/Swiss-Prot/P) Details

Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

O14732

Interaction Score

0.933

Q9HB40

(UniProtKB/Swiss-Prot/P) Details

Retinoid-inducible serine carboxypeptidase

O14732

Interaction Score

0.927

B7Z1U7

(UniProtKB/TrEmbl/P) Details

RNA binding protein fox-1 homolog

O14732

Interaction Score

0.927

Q9BS48

(UniProtKB/TrEmbl/P) Details

HSF2 protein

O14732

Interaction Score

0.907

Q53FC3

(UniProtKB/TrEmbl/P) Details

Programmed cell death 6 variant

O14732

Interaction Score

0.897

Q9BW91

(UniProtKB/Swiss-Prot/P) Details

ADP-ribose pyrophosphatase, mitochondrial

O14732

Interaction Score

0.86

P61604

(UniProtKB/Swiss-Prot/P) Details

10 kDa heat shock protein, mitochondrial

O14732

Interaction Score

0.859

Q15915

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein ZIC 1

O14732

Interaction Score

0.847

P01160

(UniProtKB/Swiss-Prot/P) Details

Natriuretic peptides A

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.86	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Mast cell granule (GO:0042629)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.991	Unknown: non-traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.991	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.991	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.991	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.991	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14732

Interaction Score

0.842

Q8NG26

(UniProtKB/TrEmbl/P) Details

Putative nudix hydrolyase

O14732

Interaction Score

0.797

Q92956

(UniProtKB/Swiss-Prot/P) Details

Tumor necrosis factor receptor superfamily member 14

O14732

Interaction Score

0.797

J3QQX2

(UniProtKB/TrEmbl/P) Details

Rho GDP-dissociation inhibitor 1

O14732

Interaction Score

0.797

Q6PKD3

(UniProtKB/TrEmbl/P) Details

RDX protein

O14732

Interaction Score

0.797

A0A087WZ38

(UniProtKB/TrEmbl/P) Details

Programmed cell death protein 6

O14732

Interaction Score

0.797

A0A024QZ42

(UniProtKB/TrEmbl/P) Details

HCG1985580, isoform CRA_c

O14732

Interaction Score

0.752

Q96KB3

(UniProtKB/TrEmbl/P) Details

cDNA FLJ14389 fis, clone HEMBA1002876

O14732

Interaction Score

0.64

A0A0C4DGL3

(UniProtKB/TrEmbl/P) Details

Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

O14732

Interaction Score

0.64

H0YNW5

(UniProtKB/TrEmbl/P) Details

Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

O14732

Interaction Score

0.56

Q6NTA2

(UniProtKB/TrEmbl/P) Details

HNRNPL protein

O14732

Interaction Score

Q9UNA3

(UniProtKB/Swiss-Prot/P) Details

Alpha-1,4-N-acetylglucosaminyltransferase

O14732

Interaction Score

Q6PI42

(UniProtKB/TrEmbl/P) Details

Glutathione peroxidase

O14732

Interaction Score

Q9H2J9

(UniProtKB/TrEmbl/P) Details

DC39

O14732

Interaction Score

Q9HBV2

(UniProtKB/Swiss-Prot/P) Details

Sperm acrosome membrane-associated protein 1

O14732

Interaction Score

A0A140VJW2

(UniProtKB/TrEmbl/P) Details

Stathmin

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O14732

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

O14732

Q99497

Protein/nucleic acid deglycase DJ-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14732

Q04760

Lactoylglutathione lyase

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14732

P29218

Inositol monophosphatase 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14732

P10599

Thioredoxin

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14732

P14866

Heterogeneous nuclear ribonucleoprotein L

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14732

Q8TBC4

NEDD8-activating enzyme E1 catalytic subunit

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14732

P09972

Fructose-bisphosphate aldolase C

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14732

O95336

6-phosphogluconolactonase

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14732

P04075

Fructose-bisphosphate aldolase A

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14732

P16949

Stathmin

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14732

Q13310

Polyadenylate-binding protein 4

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14732

O75340

Programmed cell death protein 6

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14732