O14950

Myosin regulatory light chain 12B // UniProt Profile

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Species	H. sapiens
Number of Interactions	122 / 172
Average Interaction Score	0.882

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Apical part of cell (GO:0045177)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Fibrillar center (GO:0001650)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Z disc (GO:0030018)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.998	Experimental: experimental	Organelle	PubMed
Cytosol	Myosin II complex (GO:0016460)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Stress fiber (GO:0001725)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Brush border (GO:0005903)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.998	Unknown: HDA	GO	PubMed

First-Neighbour Network Visualization

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Interactions

All Details

O14950

Interaction Score

P60709

(UniProtKB/Swiss-Prot/P) Details

Actin, cytoplasmic 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.979	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Dense body (GO:0097433)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	NuA4 histone acetyltransferase complex (GO:0035267)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cortical cytoskeleton (GO:0030863)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromatin (GO:0000790)	0.999	Unknown: HDA	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.902	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.902	Unknown: HDA	GO	PubMed
Extracellular	Blood microparticle (GO:0072562)	0.902	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.979	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.979	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.979	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Vesicle (GO:0031982)	1	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.979	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O14950

Interaction Score

P60484

(UniProtKB/Swiss-Prot/P) Details

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Schmidt-Lanterman incisure (GO:0043220)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Myelin sheath adaxonal region (GO:0035749)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	PML body (GO:0016605)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell projection (GO:0042995)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Neuron projection (GO:0043005)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Internal side of plasma membrane (GO:0009898)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

P35579

(UniProtKB/Swiss-Prot/P) Details

Myosin-9

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell leading edge (GO:0031252)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cleavage furrow (GO:0032154)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Signalosome (GO:0008180)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Spindle (GO:0005819)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Myosin II filament (GO:0097513)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Myosin II complex (GO:0016460)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Stress fiber (GO:0001725)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Actomyosin (GO:0042641)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Actomyosin contractile ring (GO:0005826)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Uropod (GO:0001931)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Ruffle (GO:0001726)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Brush border (GO:0005903)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.96	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Immunological synapse (GO:0001772)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integrin complex (GO:0008305)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Cell-cell adherens junction (GO:0005913)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Neuromuscular junction (GO:0031594)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

Q99497

(UniProtKB/Swiss-Prot/P) Details

Protein/nucleic acid deglycase DJ-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cell body (GO:0044297)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.999	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrial intermembrane space (GO:0005758)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrial respiratory chain complex I (GO:0005747)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	PML body (GO:0016605)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromatin (GO:0000785)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Axon (GO:0030424)	0.897	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane raft (GO:0045121)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell-cell adherens junction (GO:0005913)	0.897	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

O95425

(UniProtKB/Swiss-Prot/P) Details

Supervillin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cleavage furrow (GO:0032154)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Experimental: experimental	Organelle	PubMed
Cytosol	Costamere (GO:0043034)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Podosome (GO:0002102)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Invadopodium (GO:0071437)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

Q9H8V3

(UniProtKB/Swiss-Prot/P) Details

Protein ECT2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cleavage furrow (GO:0032154)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centralspindlin complex (GO:0097149)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Mitotic spindle (GO:0072686)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell-cell junction (GO:0005911)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Tight junction (GO:0005923)	0.992	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

O60260

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase parkin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ubiquitin ligase complex (GO:0000151)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	LUBAC complex (GO:0071797)	1	Predicted: inferred from physical interaction	GO	PubMed
Cytosol	SCF ubiquitin ligase complex (GO:0019005)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Aggresome (GO:0016235)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: inferred from mutant phenotype	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Neuron projection (GO:0043005)	0.8	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.7	Predicted: pTarget method	LOCATE	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

O60506

(UniProtKB/Swiss-Prot/P) Details

Heterogeneous nuclear ribonucleoprotein Q

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	GAIT complex (GO:0097452)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Histone pre-mRNA 3'end processing complex (GO:0071204)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	CRD-mediated mRNA stability complex (GO:0070937)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Catalytic step 2 spliceosome (GO:0071013)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.86	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

P27348

(UniProtKB/Swiss-Prot/P) Details

14-3-3 protein theta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.657	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.657	Unknown: HDA	GO	PubMed
Membrane	Synapse (GO:0045202)	0.657	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

Q14145

(UniProtKB/Swiss-Prot/P) Details

Kelch-like ECH-associated protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cul3-RING ubiquitin ligase complex (GO:0031463)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Midbody (GO:0030496)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Actin filament (GO:0005884)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

Q9NQW6

(UniProtKB/Swiss-Prot/P) Details

Anillin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Midbody (GO:0030496)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Actomyosin contractile ring (GO:0005826)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Bleb (GO:0032059)	0.992	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

Q9NR12

(UniProtKB/Swiss-Prot/P) Details

PDZ and LIM domain protein 7

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Stress fiber (GO:0001725)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Ruffle (GO:0001726)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.994	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell-cell adherens junction (GO:0005913)	0.994	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

P24941

(UniProtKB/Swiss-Prot/P) Details

Cyclin-dependent kinase 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cyclin-dependent protein kinase holoenzyme complex (GO:0000307)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Cajal body (GO:0015030)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Transcription factor complex (GO:0005667)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Chromosome, telomeric region (GO:0000781)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Condensed chromosome (GO:0000793)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Y chromosome (GO:0000806)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	X chromosome (GO:0000805)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

Q7KZF4

(UniProtKB/Swiss-Prot/P) Details

Staphylococcal nuclease domain-containing protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Dense body (GO:0097433)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	RNA-induced silencing complex (GO:0016442)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Melanosome (GO:0042470)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

O14950

Interaction Score

Q07020

(UniProtKB/Swiss-Prot/P) Details

60S ribosomal protein L18

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Polysomal ribosome (GO:0042788)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytosolic large ribosomal subunit (GO:0022625)	1	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Unknown: HDA	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.972	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Rough endoplasmic reticulum (GO:0005791)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.51	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.51	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

P61088

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-conjugating enzyme E2 N

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ubiquitin ligase complex (GO:0000151)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	UBC13-MMS2 complex (GO:0031372)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	UBC13-UEV1A complex (GO:0035370)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

O14950

Interaction Score

Q6IQ23

(UniProtKB/Swiss-Prot/P) Details

Pleckstrin homology domain-containing family A member 7

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Centrosome (GO:0005813)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.992	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Zonula adherens (GO:0005915)	0.992	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O14950

Interaction Score

P62993

(UniProtKB/Swiss-Prot/P) Details

Growth factor receptor-bound protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Signalosome (GO:0008180)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.86	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.971	Unknown: traceable author statement	GO	PubMed
Membrane	Extrinsic to internal side of plasma membrane (GO:0031234)	0.971	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Grb2-EGFR complex (GO:0070436)	0.971	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed
Cytosol	Vesicle membrane (GO:0012506)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell-cell junction (GO:0005911)	0.971	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

O14950

Interaction Score

Q9UQ80

(UniProtKB/Swiss-Prot/P) Details

Proliferation-associated protein 2G4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Azurophil granule lumen (GO:0035578)	0.3	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.998	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

O14950

Interaction Score

Q5S007

(UniProtKB/Swiss-Prot/P) Details

Leucine-rich repeat serine/threonine-protein kinase 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Neuronal cell body (GO:0043025)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perikaryon (GO:0043204)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Intracellular (GO:0005622)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Inclusion body (GO:0016234)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrial membrane (GO:0031966)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	External side of mitochondrial outer membrane (GO:0032473)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Golgi-associated vesicle (GO:0005798)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Multivesicular body, internal vesicle (GO:0097487)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Amphisome (GO:0044753)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Synaptic vesicle membrane (GO:0030672)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Growth cone (GO:0030426)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Microvillus (GO:0005902)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Neuron projection (GO:0043005)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Dendrite (GO:0030425)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Dendrite cytoplasm (GO:0032839)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Axon (GO:0030424)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.86	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Terminal button (GO:0043195)	1	Unknown: traceable author statement	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

P04792

(UniProtKB/Swiss-Prot/P) Details

Heat shock protein beta-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Proteasome complex (GO:0000502)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Z disc (GO:0030018)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Spindle (GO:0005819)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular space (GO:0005615)	0.86	Unknown: HDA	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.98	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.98	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.98	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.98	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

O14950

Interaction Score

O15111

(UniProtKB/Swiss-Prot/P) Details

Inhibitor of nuclear factor kappa-B kinase subunit alpha

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	IkappaB kinase complex (GO:0008385)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Internal side of plasma membrane (GO:0009898)	0.91	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	CD40 receptor complex (GO:0035631)	0.91	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

P40337

(UniProtKB/Swiss-Prot/P) Details

von Hippel-Lindau disease tumor suppressor

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	VCB complex (GO:0030891)	0.997	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Experimental: experimental	Organelle	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Unknown: non-traceable author statement	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.86	Unknown: non-traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.86	Experimental: experimental	Organelle	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

Q9BQF6

(UniProtKB/Swiss-Prot/P) Details

Sentrin-specific protease 7

O14950

Interaction Score

O43293

(UniProtKB/Swiss-Prot/P) Details

Death-associated protein kinase 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.997	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	PML body (GO:0016605)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.997	Experimental: experimental	eSLDB	PubMed
Cytosol	Actin filament (GO:0005884)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane raft (GO:0045121)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O14950

Interaction Score

O00429

(UniProtKB/Swiss-Prot/P) Details

Dynamin-1-like protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Coated pit (GO:0005905)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.988	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.94	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.997	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.997	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.997	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.997	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Peroxisome (GO:0005777)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Synaptic vesicle membrane (GO:0030672)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Microtubule (GO:0005874)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.51	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.51	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

P26373

(UniProtKB/Swiss-Prot/P) Details

60S ribosomal protein L13

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytosolic ribosome (GO:0022626)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosolic large ribosomal subunit (GO:0022625)	0.999	Unknown: HDA	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.972	Unknown: HDA	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.972	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

P38398

(UniProtKB/Swiss-Prot/P) Details

Breast cancer type 1 susceptibility protein

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Ubiquitin ligase complex (GO:0000151)	0.996	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Ubiquitin ligase complex (GO:0000151)	0.996	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	BRCA1-A complex (GO:0070531)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	BRCA1-BARD1 complex (GO:0031436)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.996	Experimental: experimental	Organelle	PubMed
Cytosol	Gamma-tubulin ring complex (GO:0008274)	0.996	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Lateral element (GO:0000800)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

Q13616

(UniProtKB/Swiss-Prot/P) Details

Cullin-1

O14950

Interaction Score

Q3YEC7

(UniProtKB/Swiss-Prot/P) Details

Rab-like protein 6

O14950

Interaction Score

Q70EL2

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase 45

O14950

Interaction Score

Q7Z406

(UniProtKB/Swiss-Prot/P) Details

Myosin-14

O14950

Interaction Score

P24844

(UniProtKB/Swiss-Prot/P) Details

Myosin regulatory light polypeptide 9

O14950

Interaction Score

Q01518

(UniProtKB/Swiss-Prot/P) Details

Adenylyl cyclase-associated protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.997	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	0.997	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Peroxisome (GO:0005777)	0.997	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Azurophil granule lumen (GO:0035578)	0.3	Unknown: traceable author statement	GO	PubMed
Cytosol	Cortical actin cytoskeleton (GO:0030864)	0.997	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.902	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.997	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.902	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

Q9NQC7

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase CYLD

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.96	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Spindle (GO:0005819)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule organizing center (GO:0005815)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cilium basal body (GO:0036064)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasmic microtubule (GO:0005881)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Extrinsic to internal side of plasma membrane (GO:0031234)	0.96	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

Q01968

(UniProtKB/Swiss-Prot/P) Details

Inositol polyphosphate 5-phosphatase OCRL-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Coated pit (GO:0005905)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi stack (GO:0005795)	0.998	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi-associated vesicle (GO:0005798)	0.998	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Phagocytic vesicle membrane (GO:0030670)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Clathrin-coated vesicle (GO:0030136)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Photoreceptor outer segment (GO:0001750)	0.96	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O14950

Interaction Score

P62736

(UniProtKB/Swiss-Prot/P) Details

Actin, aortic smooth muscle

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cell body (GO:0044297)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Smooth muscle contractile fiber (GO:0030485)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Lamellipodium (GO:0030027)	0.982	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Filopodium (GO:0030175)	0.982	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular space (GO:0005615)	0.3	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.982	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O14950

Interaction Score

Q9NX55

(UniProtKB/Swiss-Prot/P) Details

Huntingtin-interacting protein K

O14950

Interaction Score

P49407

(UniProtKB/Swiss-Prot/P) Details

Beta-arrestin-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Coated pit (GO:0005905)	0.986	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.986	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.986	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	0.986	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.931	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	0.986	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.931	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	0.931	Unknown: traceable author statement	GO	PubMed
Nucleus	Chromatin (GO:0000785)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Pseudopodium (GO:0031143)	0.984	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendritic spine (GO:0043197)	0.984	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.984	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.984	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.984	Experimental: experimental	Organelle	PubMed
Membrane	Heterotrimeric G-protein complex (GO:0005834)	0.984	Unknown: traceable author statement	GO	PubMed
Membrane	Basolateral plasma membrane (GO:0016323)	0.984	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic membrane (GO:0045211)	0.984	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.999

Q14258

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin/ISG15 ligase TRIM25

O14950

Interaction Score

0.999

Q6P1J9

(UniProtKB/Swiss-Prot/P) Details

Parafibromin

O14950

Interaction Score

0.999

P17931

(UniProtKB/Swiss-Prot/P) Details

Galectin-3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Spliceosomal complex (GO:0005681)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Secretory granule membrane (GO:0030667)	0.79	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.98	Unknown: HDA	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.98	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.98	Unknown: HDA	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.98	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.999	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.999	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Immunological synapse (GO:0001772)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.972	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.999

P09651

(UniProtKB/Swiss-Prot/P) Details

Heterogeneous nuclear ribonucleoprotein A1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	0.972	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Spliceosomal complex (GO:0005681)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Catalytic step 2 spliceosome (GO:0071013)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.972	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.999

Q14457

(UniProtKB/Swiss-Prot/P) Details

Beclin-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	eSLDB	PubMed
Cytosol	Pre-autophagosomal structure (GO:0000407)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Phosphatidylinositol 3-kinase complex I (GO:0034271)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Phosphatidylinositol 3-kinase complex II (GO:0034272)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Phosphatidylinositol 3-kinase complex, class III (GO:0035032)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.86	Experimental: inferred from mutant phenotype	GO	PubMed
Mitochondrion	Mitochondrial membrane (GO:0031966)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Autophagic vacuole (GO:0005776)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Phagocytic vesicle (GO:0045335)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.972	Experimental: experimental	eSLDB	PubMed
Membrane	Extrinsic to membrane (GO:0019898)	0.972	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.998

P60660

(UniProtKB/Swiss-Prot/P) Details

Myosin light polypeptide 6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Myosin complex (GO:0016459)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Unconventional myosin complex (GO:0016461)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Brush border (GO:0005903)	0.86	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.96	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.96	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed
Cytosol	Vesicle (GO:0031982)	1	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.998

P53355

(UniProtKB/Swiss-Prot/P) Details

Death-associated protein kinase 1

O14950

Interaction Score

0.998

P35749

(UniProtKB/Swiss-Prot/P) Details

Myosin-11

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Melanosome (GO:0042470)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Myosin filament (GO:0032982)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Muscle myosin complex (GO:0005859)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.998

Q12888

(UniProtKB/Swiss-Prot/P) Details

TP53-binding protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Site of double-strand break (GO:0035861)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Replication fork (GO:0005657)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Condensed chromosome kinetochore (GO:0000777)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromosome, telomeric region (GO:0000781)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.998

P49736

(UniProtKB/Swiss-Prot/P) Details

DNA replication licensing factor MCM2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Unknown: HDA	GO	PubMed
Nucleus	MCM complex (GO:0042555)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear origin of replication recognition complex (GO:0005664)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromatin (GO:0000785)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.998

Q9UGI8

(UniProtKB/Swiss-Prot/P) Details

Testin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Unknown: HDA	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.86	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.998

P42771

(UniProtKB/Swiss-Prot/P) Details

Cyclin-dependent kinase inhibitor 2A

O14950

Interaction Score

0.998

P47755

(UniProtKB/Swiss-Prot/P) Details

F-actin-capping protein subunit alpha-2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Cortical cytoskeleton (GO:0030863)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	F-actin capping protein complex (GO:0008290)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Brush border (GO:0005903)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane (GO:0016020)	0.902	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.998

P13569

(UniProtKB/Swiss-Prot/P) Details

Cystic fibrosis transmembrane conductance regulator

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.972	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.94	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.94	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum Sec complex (GO:0031205)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi-associated vesicle membrane (GO:0030660)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Recycling endosome (GO:0055037)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Recycling endosome membrane (GO:0055038)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome membrane (GO:0031901)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	0.972	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Clathrin coated vesicle membrane (GO:0030665)	1	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Chloride channel complex (GO:0034707)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.998

Q96CS2

(UniProtKB/Swiss-Prot/P) Details

HAUS augmin-like complex subunit 1

O14950

Interaction Score

0.998

Q96JB2

(UniProtKB/Swiss-Prot/P) Details

Conserved oligomeric Golgi complex subunit 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi cisterna membrane (GO:0032580)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	1	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi transport complex (GO:0017119)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Cis-Golgi network (GO:0005801)	1	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Trans-Golgi network membrane (GO:0032588)	1	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.998

P49917

(UniProtKB/Swiss-Prot/P) Details

DNA ligase 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Nonhomologous end joining complex (GO:0070419)	0.94	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	DNA ligase IV complex (GO:0032807)	1	Experimental: inferred from mutant phenotype	GO	PubMed
Nucleus	DNA-dependent protein kinase-DNA ligase 4 complex (GO:0005958)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Unknown: inferred by curator	GO	PubMed
Nucleus	Condensed chromosome (GO:0000793)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.997

Q92614

(UniProtKB/Swiss-Prot/P) Details

Unconventional myosin-XVIIIa

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.997	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment (GO:0005793)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.902	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	0.902	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Myosin complex (GO:0016459)	0.997	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Actomyosin (GO:0042641)	0.997	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.902	Unknown: HDA	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.902	Experimental: experimental	Human Proteinpedia	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.996

Q8WY64

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase MYLIP

O14950

Interaction Score

0.995

G8JLD5

(UniProtKB/TrEmbl/P) Details

Dynamin-1-like protein

O14950

Interaction Score

0.995

Q96H55

(UniProtKB/Swiss-Prot/P) Details

Unconventional myosin-XIX

O14950

Interaction Score

0.995

P21796

(UniProtKB/Swiss-Prot/P) Details

Voltage-dependent anion-selective channel protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Unknown: HDA	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrial nucleoid (GO:0042645)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Pore complex (GO:0046930)	1	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrial permeability transition pore complex (GO:0005757)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: HDA	GO	PubMed
Secretory-pathway	Synaptic vesicle (GO:0008021)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.992	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.971	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Membrane raft (GO:0045121)	0.971	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.971	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.992	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.994

D6RBV3

(UniProtKB/TrEmbl/P) Details

Ubiquitinyl hydrolase 1

O14950

Interaction Score

0.994

Q8TCJ0

(UniProtKB/Swiss-Prot/P) Details

F-box only protein 25

O14950

Interaction Score

0.993

Q16630

(UniProtKB/Swiss-Prot/P) Details

Cleavage and polyadenylation specificity factor subunit 6

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Paraspeckles (GO:0042382)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	MRNA cleavage factor complex (GO:0005849)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	MRNA cleavage and polyadenylation specificity factor complex (GO:0005847)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Perichromatin fibrils (GO:0005726)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

O14950

Interaction Score

0.992

Q13185

(UniProtKB/Swiss-Prot/P) Details

Chromobox protein homolog 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear inner membrane (GO:0005637)	1	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Nuclear envelope (GO:0005635)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Spindle (GO:0005819)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Unknown: HDA	GO	PubMed
Nucleus	Nuclear euchromatin (GO:0005719)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear heterochromatin (GO:0005720)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear centromeric heterochromatin (GO:0031618)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Chromatin (GO:0000785)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome, centromeric region (GO:0000775)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Condensed chromosome, centromeric region (GO:0000779)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.992

Q6ZW49

(UniProtKB/Swiss-Prot/P) Details

PAX-interacting protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear matrix (GO:0016363)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Histone methyltransferase complex (GO:0035097)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	MLL3/4 complex (GO:0044666)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.992

Q9H334

(UniProtKB/Swiss-Prot/P) Details

Forkhead box protein P1

O14950

Interaction Score

0.99

E7ESI2

(UniProtKB/TrEmbl/P) Details

Cyclin-dependent kinase 2

O14950

Interaction Score

0.99

G3V5T9

(UniProtKB/TrEmbl/P) Details

Cyclin-dependent kinase 2, isoform CRA_c

O14950

Interaction Score

0.99

Q504Q3

(UniProtKB/Swiss-Prot/P) Details

PAN2-PAN3 deadenylation complex catalytic subunit PAN2

O14950

Interaction Score

0.99

P78318

(UniProtKB/Swiss-Prot/P) Details

Immunoglobulin-binding protein 1

O14950

Interaction Score

0.988

Q9H5I1

(UniProtKB/Swiss-Prot/P) Details

Histone-lysine N-methyltransferase SUV39H2

O14950

Interaction Score

0.987

Q6AHZ1

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 518A

O14950

Interaction Score

0.987

Q12931

(UniProtKB/Swiss-Prot/P) Details

Heat shock protein 75 kDa, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial matrix (GO:0005759)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial intermembrane space (GO:0005758)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.94	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

, PubMed

O14950

Interaction Score

0.986

H0Y4Z8

(UniProtKB/TrEmbl/P) Details

Chromosome 9 open reading frame 86, isoform CRA_b

O14950

Interaction Score

0.986

A4D0V4

(UniProtKB/TrEmbl/P) Details

Capping protein (Actin filament) muscle Z-line, alpha 2, isoform CRA_b

O14950

Interaction Score

0.98

Q6NUN9

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 746

O14950

Interaction Score

0.979

P19320

(UniProtKB/Swiss-Prot/P) Details

Vascular cell adhesion protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Apical part of cell (GO:0045177)	0.972	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Podosome (GO:0002102)	0.972	Experimental: inferred from direct assay	GO	PubMed
Membrane	Microvillus (GO:0005902)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Filopodium (GO:0030175)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.988	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.988	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	1	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Sarcolemma (GO:0042383)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	External side of plasma membrane (GO:0009897)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex (GO:0071065)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.972	Unknown: HDA	GO	PubMed
Membrane	Cell junction (GO:0030054)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.979

Q00325

(UniProtKB/Swiss-Prot/P) Details

Phosphate carrier protein, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.979	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.972	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.979	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.979	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.979	Experimental: experimental	Organelle	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.979	Unknown: traceable author statement	GO	PubMed
Cytosol	Organelle inner membrane (GO:0019866)	0.972	Experimental: experimental	Organelle	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.972	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.972

P08047

(UniProtKB/Swiss-Prot/P) Details

Transcription factor Sp1

O14950

Interaction Score

0.97

Q14676

(UniProtKB/Swiss-Prot/P) Details

Mediator of DNA damage checkpoint protein 1

O14950

Interaction Score

0.96

Q00403

(UniProtKB/Swiss-Prot/P) Details

Transcription initiation factor IIB

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
N/A	Transcriptional preinitiation complex (GO:0097550)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	RNA polymerase II transcription factor complex (GO:0090575)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Transcription factor TFIID complex (GO:0005669)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Protein-DNA complex (GO:0032993)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.96

Q9UJU5

(UniProtKB/Swiss-Prot/P) Details

Forkhead box protein D3

O14950

Interaction Score

0.958

B3KWH4

(UniProtKB/TrEmbl/P) Details

cDNA FLJ43092 fis, clone COLON2002520, highly similar to Myosin-14

O14950

Interaction Score

0.953

B7Z645

(UniProtKB/TrEmbl/P) Details

Synaptotagmin binding, cytoplasmic RNA interacting protein, isoform CRA_b

O14950

Interaction Score

0.952

Q8N726

(UniProtKB/Swiss-Prot/P) Details

Tumor suppressor ARF

O14950

Interaction Score

0.948

A6NNK5

(UniProtKB/TrEmbl/P) Details

TP53-binding protein 1

O14950

Interaction Score

0.929

O95168

(UniProtKB/Swiss-Prot/P) Details

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Unknown: traceable author statement	GO	PubMed
Mitochondrion	Mitochondrial respiratory chain complex I (GO:0005747)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.902

A1L2Z2

(UniProtKB/TrEmbl/P) Details

MYH14 protein

O14950

Interaction Score

0.886

Q15751

(UniProtKB/Swiss-Prot/P) Details

Probable E3 ubiquitin-protein ligase HERC1

O14950

Interaction Score

0.876

Q8N490

(UniProtKB/Swiss-Prot/P) Details

Probable hydrolase PNKD

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.988	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.998	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.988	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.988	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: experimental	Human Proteinpedia	PubMed

Interaction Source Database:

HPRD

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.874

Q569J5

(UniProtKB/TrEmbl/P) Details

SVIL protein

O14950

Interaction Score

0.874

Q8N2P0

(UniProtKB/TrEmbl/P) Details

cDNA FLJ90088 fis, clone HEMBA1005246

O14950

Interaction Score

0.859

P01730

(UniProtKB/Swiss-Prot/P) Details

T-cell surface glycoprotein CD4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	T cell receptor complex (GO:0042101)	1	Unknown: non-traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.952	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	0.952	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.952	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Early endosome (GO:0005769)	0.952	Unknown: traceable author statement	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.8	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Clathrin coated vesicle membrane (GO:0030665)	0.952	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.988	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.988	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane raft (GO:0045121)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	External side of plasma membrane (GO:0009897)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.843

P02751

(UniProtKB/Swiss-Prot/P) Details

Fibronectin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.971	Predicted: SVM decision tree	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum lumen (GO:0005788)	0.971	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment (GO:0005793)	0.971	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.79	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Platelet alpha granule lumen (GO:0031093)	0.971	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	1	Unknown: non-traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	1	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Extracellular	Extracellular space (GO:0005615)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Fibrinogen complex (GO:0005577)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Blood microparticle (GO:0072562)	1	Unknown: HDA	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	1	Experimental: experimental	MatrixDB	PubMed
Extracellular	Basement membrane (GO:0005604)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Membrane	Apical plasma membrane (GO:0016324)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.79	Unknown: HDA	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.835

P31040

(UniProtKB/Swiss-Prot/P) Details

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: pTarget method	LOCATE	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial inner membrane (GO:0005743)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Mitochondrion	Mitochondrial respiratory chain complex II (GO:0005749)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.8	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.958	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane succinate dehydrogenase complex (GO:0045282)	0.958	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.798

P82921

(UniProtKB/Swiss-Prot/P) Details

28S ribosomal protein S21, mitochondrial

O14950

Interaction Score

0.798

P14927

(UniProtKB/Swiss-Prot/P) Details

Cytochrome b-c1 complex subunit 7

O14950

Interaction Score

0.768

A0A0C4DGV9

(UniProtKB/TrEmbl/P) Details

DNA ligase

O14950

Interaction Score

0.768

G3XAG3

(UniProtKB/TrEmbl/P) Details

Cyclin-dependent kinase inhibitor 2A (Melanoma, p16, inhibits CDK4), isoform CRA_a

O14950

Interaction Score

0.768

A0A0B4J2F3

(UniProtKB/TrEmbl/P) Details

Forkhead box protein P1

O14950

Interaction Score

0.768

Q548T7

(UniProtKB/TrEmbl/P) Details

12CC4

O14950

Interaction Score

0.768

Q8TEA2

(UniProtKB/TrEmbl/P) Details

cDNA FLJ23741 fis, clone HEP15377

O14950

Interaction Score

0.699

O60739

(UniProtKB/Swiss-Prot/P) Details

Eukaryotic translation initiation factor 1b

O14950

Interaction Score

0.699

Q6FG85

(UniProtKB/TrEmbl/P) Details

Eukaryotic translation initiation factor 1B, isoform CRA_a

O14950

Interaction Score

0.699

Q5TIA5

(UniProtKB/TrEmbl/P) Details

E3 ubiquitin-protein ligase MYLIP

O14950

Interaction Score

0.699

Q17RV3

(UniProtKB/TrEmbl/P) Details

Leucine-rich repeat kinase 2

O14950

Interaction Score

0.699

Q59H88

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

O14950

Interaction Score

0.699

Q9NYE8

(UniProtKB/TrEmbl/P) Details

Jak3 N-terminal-associated protein MAJN

O14950

Interaction Score

0.699

A4D0U5

(UniProtKB/TrEmbl/P) Details

Testis derived transcript (3 LIM domains), isoform CRA_d

O14950

Interaction Score

0.672

Q59GL1

(UniProtKB/TrEmbl/P) Details

Synaptotagmin binding, cytoplasmic RNA interacting protein variant

O14950

Interaction Score

0.672

A1Z5I9

(UniProtKB/TrEmbl/P) Details

Mediator of DNA damage checkpoint 1 variant 1

O14950

Interaction Score

0.656

P13612

(UniProtKB/Swiss-Prot/P) Details

Integrin alpha-4

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Growth cone (GO:0030426)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	1	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.51	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O14950

Interaction Score

0.48

Q99714

(UniProtKB/Swiss-Prot/P) Details

3-hydroxyacyl-CoA dehydrogenase type-2

O14950

Interaction Score

0.299

O94925

(UniProtKB/Swiss-Prot/P) Details

Glutaminase kidney isoform, mitochondrial

O14950

Interaction Score

0.21

Q6MZF9

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686J11229

O14950

Interaction Score

Q99768

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein

O14950

Interaction Score

Q68D38

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686O15119

O14950

Interaction Score

Q53FS6

(UniProtKB/TrEmbl/P) Details

TNF receptor-associated protein 1 variant

O14950

Interaction Score

A0A024QZ30

(UniProtKB/TrEmbl/P) Details

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

O14950

Interaction Score

D6RFM5

(UniProtKB/TrEmbl/P) Details

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

O14950

Interaction Score

A0A024R730

(UniProtKB/TrEmbl/P) Details

Cystic fibrosis transmembrane conductance regulator

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O14950

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

O14950

P60709

Actin, cytoplasmic 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14950

P60484

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14950

P35579

Myosin-9

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14950

Q99497

Protein/nucleic acid deglycase DJ-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14950

O95425

Supervillin

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14950

Q9H8V3

Protein ECT2

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14950

O60260

E3 ubiquitin-protein ligase parkin

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14950

O60506

Heterogeneous nuclear ribonucleoprotein Q

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14950

P27348

14-3-3 protein theta

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14950

Q14145

Kelch-like ECH-associated protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14950

Q9NQW6

Anillin

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14950

Q9NR12

PDZ and LIM domain protein 7

Localizations:

Interaction Source Database:

Interaction Source Publication:

O14950