O43307

Rho guanine nucleotide exchange factor 9 // UniProt Profile

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Species	H. sapiens
Number of Interactions	12 / 13
Average Interaction Score	0.71

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.996	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

O43307

Interaction Score

0.997

Q9NQX3

(UniProtKB/Swiss-Prot/P) Details

Gephyrin

O43307

Interaction Score

0.997

P14866

(UniProtKB/Swiss-Prot/P) Details

Heterogeneous nuclear ribonucleoprotein L

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Ribonucleoprotein complex (GO:0030529)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Ribonucleoprotein granule (GO:0035770)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O43307

Interaction Score

0.995

Q9HAU0

(UniProtKB/Swiss-Prot/P) Details

Pleckstrin homology domain-containing family A member 5

O43307

Interaction Score

0.99

Q9HCE7

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase SMURF1

O43307

Interaction Score

0.969

Q9UBB9

(UniProtKB/Swiss-Prot/P) Details

Tuftelin-interacting protein 11

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.972	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Spliceosomal complex (GO:0005681)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	U2-type post-mRNA release spliceosomal complex (GO:0071008)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Catalytic step 2 spliceosome (GO:0071013)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular matrix (GO:0031012)	0.86	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O43307

Interaction Score

0.966

Q9NU19

(UniProtKB/Swiss-Prot/P) Details

TBC1 domain family member 22B

O43307

Interaction Score

0.954

Q07666

(UniProtKB/Swiss-Prot/P) Details

KH domain-containing, RNA-binding, signal transduction-associated protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.86	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.86	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.972	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	0.972	Experimental: inferred from direct assay	GO	PubMed
Membrane	Grb2-Sos complex (GO:0070618)	0.972	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O43307

Interaction Score

0.952

Q86YD7

(UniProtKB/Swiss-Prot/P) Details

Protein FAM90A1

O43307

Interaction Score

0.697

Q3SY00

(UniProtKB/Swiss-Prot/P) Details

Testis-specific protein 10-interacting protein

O43307

Interaction Score

Q6NTA2

(UniProtKB/TrEmbl/P) Details

HNRNPL protein

O43307

Interaction Score

Q8IYA8

(UniProtKB/Swiss-Prot/P) Details

Interactor of HORMAD1 protein 1

O43307

Interaction Score

P41182

(UniProtKB/Swiss-Prot/P) Details

B-cell lymphoma 6 protein

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O43307

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

O43307

Q9NQX3

Gephyrin

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43307

P14866

Heterogeneous nuclear ribonucleoprotein L

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43307

Q9HAU0

Pleckstrin homology domain-containing family A member 5

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43307

Q9HCE7

E3 ubiquitin-protein ligase SMURF1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43307

Q9UBB9

Tuftelin-interacting protein 11

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43307

Q9NU19

TBC1 domain family member 22B

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43307

Q07666

KH domain-containing, RNA-binding, signal transduction-associated protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43307

Q86YD7

Protein FAM90A1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43307

Q3SY00

Testis-specific protein 10-interacting protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43307

Q6NTA2

HNRNPL protein

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43307

Q8IYA8

Interactor of HORMAD1 protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43307

P41182

B-cell lymphoma 6 protein

Localizations:

Interaction Source Database:

Interaction Source Publication: