O43365

Homeobox protein Hox-A3 // UniProt Profile

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Species	H. sapiens
Number of Interactions	15 / 17
Average Interaction Score	0.683

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

O43365

Interaction Score

0.999

P54274

(UniProtKB/Swiss-Prot/P) Details

Telomeric repeat-binding factor 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nucleolus (GO:0005730)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Fibrillar center (GO:0001650)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear body (GO:0016604)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear telomere cap complex (GO:0000783)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Telosome (GO:0070187)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Spindle (GO:0005819)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Chromosome (GO:0005694)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct, BioGRID

Interaction Source Publication:

PubMed

O43365

Interaction Score

0.999

Q9BSI4

(UniProtKB/Swiss-Prot/P) Details

TERF1-interacting nuclear factor 2

O43365

Interaction Score

0.999

Q9NUX5

(UniProtKB/Swiss-Prot/P) Details

Protection of telomeres protein 1

O43365

Interaction Score

0.999

P56693

(UniProtKB/Swiss-Prot/P) Details

Transcription factor SOX-10

O43365

Interaction Score

0.999

Q13610

(UniProtKB/Swiss-Prot/P) Details

Periodic tryptophan protein 1 homolog

O43365

Interaction Score

0.999

Q9H161

(UniProtKB/Swiss-Prot/P) Details

Homeobox protein aristaless-like 4

O43365

Interaction Score

0.987

Q5MJ33

(UniProtKB/TrEmbl/P) Details

Protection of telomeres protein 1 variant 4

O43365

Interaction Score

0.859

O15145

(UniProtKB/Swiss-Prot/P) Details

Actin-related protein 2/3 complex subunit 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.86	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.86	Unknown: unspecified method	The Human Protein Atlas	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Arp2/3 protein complex (GO:0005885)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Filamentous actin (GO:0031941)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	0.902	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.902	Unknown: HDA	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.902	Unknown: HDA	GO	PubMed

Interaction Source Database:

CCSB, BioGRID, IntAct

Interaction Source Publication:

PubMed

O43365

Interaction Score

0.799

A8MTK3

(UniProtKB/TrEmbl/P) Details

POT1 protection of telomeres 1 homolog (S. pombe), isoform CRA_a

O43365

Interaction Score

0.799

B4DFJ1

(UniProtKB/TrEmbl/P) Details

cDNA FLJ53728, highly similar to TERF1-interacting nuclear factor 2

O43365

Interaction Score

0.799

B4DJV5

(UniProtKB/TrEmbl/P) Details

cDNA FLJ51513, highly similar to Periodic tryptophan protein 1 homolog

O43365

Interaction Score

A0A2R8YFH5

(UniProtKB/TrEmbl/P) Details

Protein transport protein Sec23B

O43365

Interaction Score

Q15437

(UniProtKB/Swiss-Prot/P) Details

Protein transport protein Sec23B

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.931	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	COPII vesicle coat (GO:0030127)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID, IntAct, CCSB

Interaction Source Publication:

PubMed

, PubMed

O43365

Interaction Score

Q8IUH5

(UniProtKB/Swiss-Prot/P) Details

Palmitoyltransferase ZDHHC17

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Aggresome (GO:0016235)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Aggresome (GO:0016235)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi-associated vesicle membrane (GO:0030660)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.897	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Presynaptic membrane (GO:0042734)	0.897	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID, IntAct

Interaction Source Publication:

PubMed

O43365

Interaction Score

P08236

(UniProtKB/Swiss-Prot/P) Details

Beta-glucuronidase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.79	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Lysosome (GO:0005764)	0.999	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.999	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Lysosome (GO:0005764)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Lysosomal lumen (GO:0043202)	0.999	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Azurophil granule lumen (GO:0035578)	0.79	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.972	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.972	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular space (GO:0005615)	0.972	Experimental: inferred from direct assay	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: HDA	GO	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	MatrixDB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

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O43365

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

O43365

P54274

Telomeric repeat-binding factor 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43365

Q9BSI4

TERF1-interacting nuclear factor 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43365

Q9NUX5

Protection of telomeres protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43365

P56693

Transcription factor SOX-10

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43365

Q13610

Periodic tryptophan protein 1 homolog

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43365

Q9H161

Homeobox protein aristaless-like 4

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43365

Q5MJ33

Protection of telomeres protein 1 variant 4

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43365

O15145

Actin-related protein 2/3 complex subunit 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43365

A8MTK3

POT1 protection of telomeres 1 homolog (S. pombe), isoform CRA_a

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43365

B4DFJ1

cDNA FLJ53728, highly similar to TERF1-interacting nuclear factor 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43365

B4DJV5

cDNA FLJ51513, highly similar to Periodic tryptophan protein 1 homolog

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43365

A0A2R8YFH5

Protein transport protein Sec23B

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43365