O43610

Protein sprouty homolog 3 // UniProt Profile

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Species	H. sapiens
Number of Interactions	26 / 26
Average Interaction Score	0.954

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleolus (GO:0005730)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Experimental: experimental	eSLDB	PubMed
Membrane	Membrane (GO:0016020)	0.86	Unknown: inferred from electronic annotation	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

O43610

Interaction Score

P29972

(UniProtKB/Swiss-Prot/P) Details

Aquaporin-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Apical part of cell (GO:0045177)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Brush border (GO:0005903)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Brush border membrane (GO:0031526)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.988	Experimental: experimental	MatrixDB	PubMed
Extracellular	Symbiont-containing vacuole (GO:0020003)	0.988	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Symbiont-containing vacuole membrane (GO:0020005)	0.988	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: pTarget method	LOCATE	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Sarcolemma (GO:0042383)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Basolateral plasma membrane (GO:0016323)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Basal plasma membrane (GO:0009925)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.992	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O43610

Interaction Score

O60336

(UniProtKB/Swiss-Prot/P) Details

Mitogen-activated protein kinase-binding protein 1

O43610

Interaction Score

O76011

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cuticular Ha4

O43610

Interaction Score

Q8IUH5

(UniProtKB/Swiss-Prot/P) Details

Palmitoyltransferase ZDHHC17

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Aggresome (GO:0016235)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Aggresome (GO:0016235)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi-associated vesicle membrane (GO:0030660)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle membrane (GO:0030659)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.897	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Presynaptic membrane (GO:0042734)	0.897	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O43610

Interaction Score

0.999

Q8N720

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 655

O43610

Interaction Score

0.992

Q15569

(UniProtKB/Swiss-Prot/P) Details

Dual specificity testis-specific protein kinase 1

O43610

Interaction Score

0.991

Q5T7P2

(UniProtKB/Swiss-Prot/P) Details

Late cornified envelope protein 1A

O43610

Interaction Score

0.991

Q9BYE3

(UniProtKB/Swiss-Prot/P) Details

Late cornified envelope protein 3D

O43610

Interaction Score

0.987

O14633

(UniProtKB/Swiss-Prot/P) Details

Late cornified envelope protein 2B

O43610

Interaction Score

0.985

Q92504

(UniProtKB/Swiss-Prot/P) Details

Zinc transporter SLC39A7

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.994	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.994	Predicted: pTarget method	LOCATE	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.956	Unknown: traceable author statement	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.956	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.956	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.956	Predicted: PAML algorithm	PA-GOSUB	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O43610

Interaction Score

0.983

P62760

(UniProtKB/Swiss-Prot/P) Details

Visinin-like protein 1

O43610

Interaction Score

0.975

Q9BXY8

(UniProtKB/Swiss-Prot/P) Details

Protein BEX2

O43610

Interaction Score

0.971

Q5T5B0

(UniProtKB/Swiss-Prot/P) Details

Late cornified envelope protein 3E

O43610

Interaction Score

0.971

Q5TA76

(UniProtKB/Swiss-Prot/P) Details

Late cornified envelope protein 3A

O43610

Interaction Score

0.971

Q5T754

(UniProtKB/Swiss-Prot/P) Details

Late cornified envelope protein 1F

O43610

Interaction Score

0.971

Q5T7P3

(UniProtKB/Swiss-Prot/P) Details

Late cornified envelope protein 1B

O43610

Interaction Score

0.969

Q5T749

(UniProtKB/Swiss-Prot/P) Details

Keratinocyte proline-rich protein

O43610

Interaction Score

0.96

O43593

(UniProtKB/Swiss-Prot/P) Details

Lysine-specific demethylase hairless

O43610

Interaction Score

0.956

Q9Y2K5

(UniProtKB/Swiss-Prot/P) Details

R3H domain-containing protein 2

O43610

Interaction Score

0.949

Q9Y4H4

(UniProtKB/Swiss-Prot/P) Details

G-protein-signaling modulator 3

O43610

Interaction Score

0.948

Q8NEC5

(UniProtKB/Swiss-Prot/P) Details

Cation channel sperm-associated protein 1

O43610

Interaction Score

0.942

P49639

(UniProtKB/Swiss-Prot/P) Details

Homeobox protein Hox-A1

O43610

Interaction Score

0.932

Q96SQ5

(UniProtKB/Swiss-Prot/P) Details

Zinc finger protein 587

O43610

Interaction Score

0.922

Q9H2X0

(UniProtKB/Swiss-Prot/P) Details

Chordin

O43610

Interaction Score

0.768

Q6FHY5

(UniProtKB/TrEmbl/P) Details

MEOX2 protein

O43610

Interaction Score

0.672

Q8NFJ4

(UniProtKB/TrEmbl/P) Details

Testis-specific kinase-1

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O43610

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

O43610

P29972

Aquaporin-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43610

O60336

Mitogen-activated protein kinase-binding protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43610

O76011

Keratin, type I cuticular Ha4

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43610

Q8IUH5

Palmitoyltransferase ZDHHC17

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43610

Q8N720

Zinc finger protein 655

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43610

Q15569

Dual specificity testis-specific protein kinase 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43610

Q5T7P2

Late cornified envelope protein 1A

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43610

Q9BYE3

Late cornified envelope protein 3D

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43610

O14633

Late cornified envelope protein 2B

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43610

Q92504

Zinc transporter SLC39A7

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43610

P62760

Visinin-like protein 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43610

Q9BXY8

Protein BEX2

Localizations:

Interaction Source Database:

Interaction Source Publication:

O43610