O75015

Low affinity immunoglobulin gamma Fc region receptor III-B // UniProt Profile

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Species	H. sapiens
Number of Interactions	28 / 34
Average Interaction Score	0.849

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Lysosome (GO:0005764)	0.79	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Secretory granule membrane (GO:0030667)	0.3	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.958	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.958	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	0.998	Experimental: experimental	MatrixDB	PubMed
Membrane	Anchored to membrane (GO:0031225)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.79	Unknown: HDA	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

O75015

Interaction Score

P06756

(UniProtKB/Swiss-Prot/P) Details

Integrin alpha-V

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Phagocytic vesicle (GO:0045335)	0.3	Unknown: traceable author statement	GO	PubMed
Membrane	Ruffle membrane (GO:0032587)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Microvillus membrane (GO:0031528)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Lamellipodium membrane (GO:0031258)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Filopodium membrane (GO:0031527)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	External side of plasma membrane (GO:0009897)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Alphav-beta3 integrin-IGF-1-IGF1R complex (GO:0035867)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Unknown: non-traceable author statement	GO	PubMed
Membrane	Integrin complex (GO:0008305)	1	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.972	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O75015

Interaction Score

O60462

(UniProtKB/Swiss-Prot/P) Details

Neuropilin-2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.7	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Semaphorin receptor complex (GO:0002116)	0.998	Unknown: non-traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Membrane	Axon (GO:0030424)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.958	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.958	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	0.998	Unknown: traceable author statement	GO	PubMed
Membrane	Membrane (GO:0016020)	0.998	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.998	Unknown: non-traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Unknown: traceable author statement	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O75015

Interaction Score

Q8TDW0

(UniProtKB/Swiss-Prot/P) Details

Volume-regulated anion channel subunit LRRC8C

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.972	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.999	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Ion channel complex (GO:0034702)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O75015

Interaction Score

P08637

(UniProtKB/Swiss-Prot/P) Details

Low affinity immunoglobulin gamma Fc region receptor III-A

O75015

Interaction Score

Q6NSJ5

(UniProtKB/Swiss-Prot/P) Details

Volume-regulated anion channel subunit LRRC8E

O75015

Interaction Score

0.999

Q01726

(UniProtKB/Swiss-Prot/P) Details

Melanocyte-stimulating hormone receptor

O75015

Interaction Score

0.998

P01857

(UniProtKB/Swiss-Prot/P) Details

Immunoglobulin heavy constant gamma 1

O75015

Interaction Score

0.998

P54707

(UniProtKB/Swiss-Prot/P) Details

Potassium-transporting ATPase alpha chain 2

O75015

Interaction Score

0.997

Q6YHK3

(UniProtKB/Swiss-Prot/P) Details

CD109 antigen

O75015

Interaction Score

0.996

P32189

(UniProtKB/Swiss-Prot/P) Details

Glycerol kinase

O75015

Interaction Score

0.994

P02743

(UniProtKB/Swiss-Prot/P) Details

Serum amyloid P-component

O75015

Interaction Score

0.981

Q13509

(UniProtKB/Swiss-Prot/P) Details

Tubulin beta-3 chain

O75015

Interaction Score

0.98

Q9UPZ9

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase ICK

O75015

Interaction Score

0.945

Q71U36

(UniProtKB/Swiss-Prot/P) Details

Tubulin alpha-1A chain

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.3	Unknown: HDA	GO	PubMed
Secretory-pathway	Recycling endosome (GO:0055037)	0.8	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Microtubule (GO:0005874)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasmic microtubule (GO:0005881)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Membrane raft (GO:0045121)	0.657	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Neuromuscular junction (GO:0031594)	0.657	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O75015

Interaction Score

0.93

Q7Z3T9

(UniProtKB/TrEmbl/P) Details

Neuropilin

O75015

Interaction Score

0.928

Q9Y2M5

(UniProtKB/Swiss-Prot/P) Details

Kelch-like protein 20

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cul3-RING ubiquitin ligase complex (GO:0031463)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	PML body (GO:0016605)	0.8	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.992	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Trans-Golgi network (GO:0005802)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	1	Unknown: traceable author statement	GO	PubMed
Membrane	Dendrite (GO:0030425)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Axon (GO:0030424)	0.51	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O75015

Interaction Score

0.91

Q15818

(UniProtKB/Swiss-Prot/P) Details

Neuronal pentraxin-1

O75015

Interaction Score

0.896

Q9P0S2

(UniProtKB/Swiss-Prot/P) Details

Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial

O75015

Interaction Score

0.853

Q96EX3

(UniProtKB/Swiss-Prot/P) Details

WD repeat-containing protein 34

O75015

Interaction Score

0.799

V9HWP0

(UniProtKB/TrEmbl/P) Details

Pentaxin

O75015

Interaction Score

0.79

Q9UFF9

(UniProtKB/Swiss-Prot/P) Details

CCR4-NOT transcription complex subunit 8

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular (GO:0005622)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Cytoplasmic mRNA processing body (GO:0000932)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Unknown: non-traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	CCR4-NOT complex (GO:0030014)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	CCR4-NOT core complex (GO:0030015)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O75015

Interaction Score

0.785

Q3ZCM7

(UniProtKB/Swiss-Prot/P) Details

Tubulin beta-8 chain

O75015

Interaction Score

0.766

B4E0R9

(UniProtKB/TrEmbl/P) Details

Sodium/potassium-transporting ATPase subunit alpha

O75015

Interaction Score

0.758

P24468

(UniProtKB/Swiss-Prot/P) Details

COUP transcription factor 2

O75015

Interaction Score

0.699

M9MML0

(UniProtKB/TrEmbl/P) Details

Low affinity immunoglobulin gamma Fc region receptor III-A

O75015

Interaction Score

0.553

Q53G92

(UniProtKB/TrEmbl/P) Details

Tubulin beta chain

O75015

Interaction Score

0.21

Q86UD1

(UniProtKB/Swiss-Prot/P) Details

Out at first protein homolog

O75015

Interaction Score

Q8NFW5

(UniProtKB/Swiss-Prot/P) Details

Diencephalon/mesencephalon homeobox protein 1

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O75015

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

O75015

P06756

Integrin alpha-V

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75015

O60462

Neuropilin-2

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75015

Q8TDW0

Volume-regulated anion channel subunit LRRC8C

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75015

P08637

Low affinity immunoglobulin gamma Fc region receptor III-A

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75015

Q6NSJ5

Volume-regulated anion channel subunit LRRC8E

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75015

Q01726

Melanocyte-stimulating hormone receptor

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75015

P01857

Immunoglobulin heavy constant gamma 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75015

P54707

Potassium-transporting ATPase alpha chain 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75015

Q6YHK3

CD109 antigen

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75015

P32189

Glycerol kinase

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75015

P02743

Serum amyloid P-component

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75015

Q13509

Tubulin beta-3 chain

Localizations:

Interaction Source Database:

Interaction Source Publication:

O75015