O75845

Lathosterol oxidase    //   UniProt Profile 

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Species

H. sapiens

Number of Interactions

15 / 22

Average Interaction Score

0.947

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytosol (GO:0005829) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.995 Predicted: pTarget method LOCATE PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.995 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.995 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.995 Predicted: inferred from biological aspect of ancestor GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.958 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

O75845

Interaction Score
1

Q9GZM5

(UniProtKB/Swiss-Prot/P) Details

Protein YIPF3

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.96 Experimental: experimental eSLDB PubMed 
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.998 Experimental: experimental Human Proteinpedia PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.998 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Transport vesicle (GO:0030133) 0.998 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.853 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.853 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.853 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75845

Interaction Score
1

Q92633

(UniProtKB/Swiss-Prot/P) Details

Lysophosphatidic acid receptor 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Neuronal cell body (GO:0043025) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 0.96 Experimental: experimental Organelle PubMed 
Nucleus Nuclear speck (GO:0016607) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endosome (GO:0005768) 0.96 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endocytic vesicle (GO:0030139) 0.96 Experimental: inferred from direct assay GO PubMed 
Membrane Dendritic shaft (GO:0043198) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Dendritic spine (GO:0043197) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Predicted: inferred from sequence or structural similarity GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75845

Interaction Score
0.995

Q96FV3

(UniProtKB/Swiss-Prot/P) Details

Tetraspanin-17

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Ubiquitin ligase complex (GO:0000151) 0.86 Unknown: non-traceable author statement GO PubMed 
Cytosol Ubiquitin ligase complex (GO:0000151) 0.86 Experimental: experimental Organelle PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.91 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75845

Interaction Score
0.995

Q96G97

(UniProtKB/Swiss-Prot/P) Details

Seipin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.96 Experimental: experimental eSLDB PubMed 
Secretory-pathway Integral to endoplasmic reticulum membrane (GO:0030176) 0.96 Experimental: inferred from direct assay GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75845

Interaction Score
0.989

Q86W33

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein adipocyte-associated 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular membrane-bounded organelle (GO:0043231) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.958 Predicted: pTarget method LOCATE PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75845

Interaction Score
0.985

P32241

(UniProtKB/Swiss-Prot/P) Details

Vasoactive intestinal polypeptide receptor 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Unknown: traceable author statement GO PubMed 
Membrane Receptor complex (GO:0043235) 1 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75845

Interaction Score
0.984

Q16581

(UniProtKB/Swiss-Prot/P) Details

C3a anaphylatoxin chemotactic receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.998 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.998 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75845

Interaction Score
0.984

P41587

(UniProtKB/Swiss-Prot/P) Details

Vasoactive intestinal polypeptide receptor 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.997 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.997 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.997 Predicted: pTarget method LOCATE PubMed 
Membrane Plasma membrane (GO:0005886) 0.997 Experimental: experimental Organelle PubMed 
Membrane Plasma membrane (GO:0005886) 0.997 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.997 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75845

Interaction Score
0.984

Q8IVM8

(UniProtKB/Swiss-Prot/P) Details

Solute carrier family 22 member 9

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.996 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.996 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.996 Predicted: inferred from biological aspect of ancestor GO PubMed 
Membrane Basolateral plasma membrane (GO:0016323) 0.996 Experimental: inferred from direct assay GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75845

Interaction Score
0.981

P62079

(UniProtKB/Swiss-Prot/P) Details

Tetraspanin-5

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.988 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.988 Experimental: inferred from direct assay GO PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.988 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75845

Interaction Score
0.981

Q8TDU9

(UniProtKB/Swiss-Prot/P) Details

Relaxin-3 receptor 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.987 Experimental: experimental eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.987 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to plasma membrane (GO:0005887) 0.987 Predicted: inferred from biological aspect of ancestor GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75845

Interaction Score
0.959

Q9H8X2

(UniProtKB/Swiss-Prot/P) Details

Inositol-pentakisphosphate 2-kinase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Intracellular (GO:0005622) 0.994 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.994 Experimental: experimental eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.994 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.994 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleolus (GO:0005730) 0.998 Experimental: inferred from mutant phenotype GO PubMed 
Nucleus DNA-directed RNA polymerase I complex (GO:0005736) 0.998 Experimental: inferred from mutant phenotype GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.998 Unknown: traceable author statement GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75845

Interaction Score
0.957

J3KNG2

(UniProtKB/TrEmbl/P) Details

Tetraspanin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75845

Interaction Score
0.766

Q5VZX0

(UniProtKB/TrEmbl/P) Details

Endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2, isoform CRA_a

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Integral to membrane (GO:0016021) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O75845

Interaction Score
0.64

A0A024R7Q6

(UniProtKB/TrEmbl/P) Details

Tetraspanin

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015