O95389

WNT1-inducible-signaling pathway protein 3    //   UniProt Profile 

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Species

 H. sapiens

Number of Interactions

 9 / 15

Average Interaction Score

 0.603

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.992 Experimental: experimental eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.992 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.992 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 0.987 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.987 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.987 Unknown: non-traceable author statement GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.987 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

O95389

Interaction Score
1

Q92673

(UniProtKB/Swiss-Prot/P) Details

Sortilin-related receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nuclear envelope lumen (GO:0005641) 0.96 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi cisterna (GO:0031985) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 1 Unknown: traceable author statement GO PubMed 
Secretory-pathway Trans-Golgi network (GO:0005802) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endosome (GO:0005768) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Recycling endosome (GO:0055037) 1 Experimental: inferred from mutant phenotype GO PubMed 
Secretory-pathway Early endosome (GO:0005769) 1 Experimental: inferred from mutant phenotype GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 1 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.992 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.992 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.992 Experimental: inferred from direct assay GO PubMed 
Extracellular Low-density lipoprotein particle (GO:0034362) 0.992 Unknown: inferred from electronic annotation GO PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 1 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 1 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 1 Experimental: experimental Organelle PubMed 
Membrane Integral to plasma membrane (GO:0005887) 1 Unknown: traceable author statement GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.3 Unknown: HDA GO PubMed 
Membrane Cell junction (GO:0030054) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O95389

Interaction Score
0.997

Q6UXH1

(UniProtKB/Swiss-Prot/P) Details

Cysteine-rich with EGF-like domain protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.853 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.853 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.853 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.958 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O95389

Interaction Score
0.992

Q14108

(UniProtKB/Swiss-Prot/P) Details

Lysosome membrane protein 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Cell surface (GO:0009986) 0.99 Unknown: traceable author statement GO PubMed 
Cytosol Cytosol (GO:0005829) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.832 Unknown: traceable author statement GO PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.832 Unknown: traceable author statement GO PubMed 
Secretory-pathway Late endosome membrane (GO:0031902) 0.832 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.832 Unknown: traceable author statement GO PubMed 
Cytosol Lysosome (GO:0005764) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Lysosomal lumen (GO:0043202) 0.998 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Lysosomal membrane (GO:0005765) 0.998 Unknown: traceable author statement GO PubMed 
Cytosol Lysosomal membrane (GO:0005765) 0.998 Experimental: experimental Organelle PubMed 
Secretory-pathway Clathrin coated vesicle membrane (GO:0030665) 0.832 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.99 Unknown: HDA GO PubMed 
Membrane Integral to membrane (GO:0016021) 0.99 Predicted: SVM decision tree eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.99 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.99 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.99 Experimental: experimental Organelle PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.998 Unknown: HDA GO PubMed 
Membrane Focal adhesion (GO:0005925) 0.99 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O95389

Interaction Score
0.955

Q92870

(UniProtKB/Swiss-Prot/P) Details

Amyloid-beta A4 precursor protein-binding family B member 2

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytoplasm (GO:0005737) 0.91 Predicted: PAML algorithm PA-GOSUB PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Predicted: inferred from sequence or structural similarity GO PubMed 
Nucleus Nucleus (GO:0005634) 0.982 Experimental: experimental Organelle PubMed 
Membrane Growth cone (GO:0030426) 0.981 Predicted: inferred from sequence or structural similarity GO PubMed 
Membrane Lamellipodium (GO:0030027) 0.981 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.981 Unknown: non-traceable author statement GO PubMed 
Membrane Synapse (GO:0045202) 0.981 Predicted: inferred from sequence or structural similarity GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O95389

Interaction Score
0.84

Q9H0S4

(UniProtKB/Swiss-Prot/P) Details

Probable ATP-dependent RNA helicase DDX47

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.7 Predicted: inferred from biological aspect of ancestor GO PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleolus (GO:0005730) 0.999 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleolus (GO:0005730) 0.999 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleolus (GO:0005730) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nucleoplasm (GO:0005654) 0.999 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.3 Unknown: HDA GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O95389

Interaction Score
0.64

E9PPB3

(UniProtKB/TrEmbl/P) Details

Sortilin-related receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleoplasm (GO:0005654) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Membrane Cell junction (GO:0030054) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O95389

Interaction Score
0

G5E9Y1

(UniProtKB/TrEmbl/P) Details

Amyloid beta (A4) protein-binding, family B, member 2 (Fe65-like), isoform CRA_c

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Mitochondrion Mitochondrion (GO:0005739) 0.8 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O95389

Interaction Score
0

Q5I0G1

(UniProtKB/TrEmbl/P) Details

APBB2 protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

O95389

Interaction Score
0

O15514

(UniProtKB/Swiss-Prot/P) Details

DNA-directed RNA polymerase II subunit RPB4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasmic mRNA processing body (GO:0000932) 0.94 Predicted: inferred from biological aspect of ancestor GO PubMed 
Cytosol Cytosol (GO:0005829) 0.94 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental Organelle PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleoplasm (GO:0005654) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear speck (GO:0016607) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nuclear speck (GO:0016607) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus DNA-directed RNA polymerase II, core complex (GO:0005665) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus RNA polymerase complex (GO:0030880) 1 Experimental: experimental Organelle PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015