O95476

CTD nuclear envelope phosphatase 1 // UniProt Profile

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Species	H. sapiens
Number of Interactions	90 / 116
Average Interaction Score	0.924

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Nem1-Spo7 phosphatase complex (GO:0071595)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lipid particle (GO:0005811)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lipid particle (GO:0005811)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.988	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear envelope (GO:0005635)	0.988	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.94	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.3	Unknown: inferred from electronic annotation	GO	PubMed

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.

Interactions

All Details

O95476

Interaction Score

O00165

(UniProtKB/Swiss-Prot/P) Details

HCLS1-associated protein X-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.996	Experimental: experimental	Organelle	PubMed
Cytosol	Sarcoplasmic reticulum (GO:0016529)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasmic mRNA processing body (GO:0000932)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cell cortex (GO:0005938)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	eSLDB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: experimental	Organelle	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrial intermembrane space (GO:0005758)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrial outer membrane (GO:0005741)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.996	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear envelope (GO:0005635)	0.996	Unknown: traceable author statement	GO	PubMed
Nucleus	Transcription factor complex (GO:0005667)	0.996	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.992	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.992	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.992	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoskeleton (GO:0005856)	0.996	Experimental: experimental	Organelle	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.996	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Lamellipodium (GO:0030027)	0.958	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.958	Experimental: experimental	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.958	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

P63096

(UniProtKB/Swiss-Prot/P) Details

Guanine nucleotide-binding protein G(i) subunit alpha-1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Midbody (GO:0030496)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.7	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleolus (GO:0005730)	0.998	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.8	Experimental: experimental	Human Proteinpedia	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	1	Unknown: HDA	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane raft (GO:0045121)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: experimental	Organelle	PubMed
Membrane	Heterotrimeric G-protein complex (GO:0005834)	0.999	Unknown: traceable author statement	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

Q8WXH0

(UniProtKB/Swiss-Prot/P) Details

Nesprin-2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Aggresome (GO:0016235)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Sarcoplasmic reticulum (GO:0016529)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Sarcoplasmic reticulum membrane (GO:0033017)	1	Unknown: inferred from electronic annotation	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear outer membrane (GO:0005640)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear envelope (GO:0005635)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	SUN-KASH complex (GO:0034993)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear lumen (GO:0031981)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Z disc (GO:0030018)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intermediate filament cytoskeleton (GO:0045111)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Lamellipodium membrane (GO:0031258)	0.994	Experimental: inferred from direct assay	GO	PubMed
Membrane	Filopodium membrane (GO:0031527)	0.994	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	1	Unknown: HDA	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.994	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

Q9NRG9

(UniProtKB/Swiss-Prot/P) Details

Aladin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	1	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Pore complex (GO:0046930)	0.8	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Unknown: HDA	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear envelope (GO:0005635)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear pore (GO:0005643)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Centrosome (GO:0005813)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.3	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

Q14571

(UniProtKB/Swiss-Prot/P) Details

Inositol 1,4,5-trisphosphate receptor type 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.991	Predicted: SVM decision tree	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.991	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Sarcoplasmic reticulum membrane (GO:0033017)	0.991	Experimental: inferred from mutant phenotype	GO	PubMed
Cytosol	Cell cortex (GO:0005938)	0.991	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Platelet dense tubular network membrane (GO:0031095)	0.991	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.999	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

P16615

(UniProtKB/Swiss-Prot/P) Details

Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Sarcoplasmic reticulum (GO:0016529)	0.952	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Sarcoplasmic reticulum membrane (GO:0033017)	0.952	Unknown: traceable author statement	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.952	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Platelet dense tubular network membrane (GO:0031095)	0.952	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.994	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.994	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	1	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.998	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.998	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Experimental: experimental	Organelle	PubMed
Membrane	Plasma membrane (GO:0005886)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Extrinsic to internal side of plasma membrane (GO:0031234)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	0.998	Unknown: traceable author statement	GO	PubMed
Cytosol	Vesicle membrane (GO:0012506)	0.952	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

Q9HC62

(UniProtKB/Swiss-Prot/P) Details

Sentrin-specific protease 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.998	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.94	Predicted: SVM decision tree	eSLDB	PubMed
Mitochondrion	Pore complex (GO:0046930)	0.94	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	0.999	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear membrane (GO:0031965)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear pore (GO:0005643)	0.999	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	PML body (GO:0016605)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

Q14643

(UniProtKB/Swiss-Prot/P) Details

Inositol 1,4,5-trisphosphate receptor type 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Calcineurin complex (GO:0005955)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Endomembrane system (GO:0012505)	0.999	Experimental: experimental	Organelle	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.999	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Sarcoplasmic reticulum (GO:0016529)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Perinuclear region of cytoplasm (GO:0048471)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Platelet dense tubular network (GO:0031094)	0.999	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Platelet dense tubular network membrane (GO:0031095)	0.999	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear inner membrane (GO:0005637)	0.51	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.998	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Platelet dense granule membrane (GO:0031088)	0.998	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Transport vesicle membrane (GO:0030658)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Postsynaptic density (GO:0014069)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.994	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.994	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

Q9BTX1

(UniProtKB/Swiss-Prot/P) Details

Nucleoporin NDC1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear envelope (GO:0005635)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	Nuclear pore (GO:0005643)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	NDC1 complex (GO:0070762)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Spindle pole body (GO:0005816)	0.992	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Actin cytoskeleton (GO:0015629)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.996	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.996	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.996	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.996	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

P16435

(UniProtKB/Swiss-Prot/P) Details

NADPH--cytochrome P450 reductase

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.8	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.987	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.987	Experimental: experimental	Organelle	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.987	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.853	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.853	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.853	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

Q14573

(UniProtKB/Swiss-Prot/P) Details

Inositol 1,4,5-trisphosphate receptor type 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Myelin sheath (GO:0043209)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Neuronal cell body (GO:0043025)	0.987	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Apical part of cell (GO:0045177)	0.987	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.987	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.987	Unknown: unspecified method	The Human Protein Atlas	PubMed
Cytosol	Platelet dense tubular network membrane (GO:0031095)	0.987	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleolus (GO:0005730)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear outer membrane (GO:0005640)	0.853	Predicted: inferred from sequence or structural similarity	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.853	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.992	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.992	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.992	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.992	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Brush border (GO:0005903)	1	Predicted: inferred from sequence or structural similarity	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	1	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	1	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to plasma membrane (GO:0005887)	1	Experimental: inferred from direct assay	GO	PubMed
Membrane	Receptor complex (GO:0043235)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

Q9UHD9

(UniProtKB/Swiss-Prot/P) Details

Ubiquilin-2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.998	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.998	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.937	Predicted: SVM decision tree	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	0.937	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.937	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Autophagic vacuole (GO:0005776)	0.998	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: inferred from direct assay	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed

O95476

Interaction Score

Q9HBM0

(UniProtKB/Swiss-Prot/P) Details

Vezatin

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.988	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.988	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.96	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.79	Predicted: pTarget method	LOCATE	PubMed
Secretory-pathway	Acrosomal vesicle (GO:0001669)	0.79	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.897	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.897	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Adherens junction (GO:0005912)	0.897	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

Q86Y07

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein kinase VRK2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.94	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Mitochondrion	Mitochondrial membrane (GO:0031966)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.96	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Macromolecular complex (GO:0032991)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.992	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.992	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.86	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.86	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

P09619

(UniProtKB/Swiss-Prot/P) Details

Platelet-derived growth factor receptor beta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.992	Predicted: inferred from sequence or structural similarity	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.992	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nucleus (GO:0005634)	0.7	Predicted: inferred from sequence or structural similarity	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.972	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Golgi apparatus (GO:0005794)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Lysosomal lumen (GO:0043202)	0.992	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Cytoplasmic vesicle (GO:0031410)	0.972	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Unknown: traceable author statement	GO	PubMed
Membrane	Intrinsic to plasma membrane (GO:0031226)	0.999	Experimental: inferred from direct assay	GO	PubMed
Membrane	Apical plasma membrane (GO:0016324)	0.999	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Focal adhesion (GO:0005925)	0.999	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

Q9UH99

(UniProtKB/Swiss-Prot/P) Details

SUN domain-containing protein 2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.8	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Human Proteinpedia	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Integral to nuclear inner membrane (GO:0005639)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear envelope (GO:0005635)	1	Unknown: traceable author statement	GO	PubMed
Nucleus	SUN-KASH complex (GO:0034993)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endosome (GO:0005768)	0.86	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.86	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Condensed nuclear chromosome (GO:0000794)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear chromosome, telomeric region (GO:0000784)	1	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.8	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

Q9Y2U8

(UniProtKB/Swiss-Prot/P) Details

Inner nuclear membrane protein Man1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Endomembrane system (GO:0012505)	0.96	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	Organelle	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear inner membrane (GO:0005637)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Integral to nuclear inner membrane (GO:0005639)	1	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Nucleus	Integral to nuclear inner membrane (GO:0005639)	1	Experimental: experimental	Organelle	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.972	Unknown: traceable author statement	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.972	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Organelle inner membrane (GO:0019866)	0.96	Experimental: experimental	Organelle	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

Q5T8D3

(UniProtKB/Swiss-Prot/P) Details

Acyl-CoA-binding domain-containing protein 5

O95476

Interaction Score

P18031

(UniProtKB/Swiss-Prot/P) Details

Tyrosine-protein phosphatase non-receptor type 1

O95476

Interaction Score

O95897

(UniProtKB/Swiss-Prot/P) Details

Noelin-2

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Secretory-pathway	Secretory pathway (GO:secretory_pathway)	0.8	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	0.992	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.988	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.988	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.988	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	0.958	Experimental: experimental	MatrixDB	PubMed
Membrane	Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex (GO:0032281)	0.958	Predicted: inferred from sequence or structural similarity	GO	PubMed
Membrane	Cell junction (GO:0030054)	0.958	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

Q8N9A8

(UniProtKB/Swiss-Prot/P) Details

Nuclear envelope phosphatase-regulatory subunit 1

O95476

Interaction Score

Q14258

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin/ISG15 ligase TRIM25

O95476

Interaction Score

Q9UBU9

(UniProtKB/Swiss-Prot/P) Details

Nuclear RNA export factor 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.972	Experimental: experimental	eSLDB	PubMed
Cytosol	Cytoplasm (GO:0005737)	0.972	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Cytosol (GO:0005829)	0.972	Unknown: traceable author statement	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Nucleus	Nuclear inclusion body (GO:0042405)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear pore (GO:0005643)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleoplasm (GO:0005654)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Nuclear speck (GO:0016607)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Transcription export complex (GO:0000346)	1	Experimental: inferred from direct assay	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

P28288

(UniProtKB/Swiss-Prot/P) Details

ATP-binding cassette sub-family D member 3

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	1	Unknown: traceable author statement	GO	PubMed
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	1	Experimental: inferred from direct assay	GO	PubMed
Mitochondrion	Mitochondrion (GO:0005739)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Cytosol	Peroxisome (GO:0005777)	1	Experimental: experimental	eSLDB	PubMed
Cytosol	Peroxisome (GO:0005777)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Peroxisome (GO:0005777)	1	Predicted: pTarget method	LOCATE	PubMed
Cytosol	Peroxisome (GO:0005777)	1	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Peroxisome (GO:0005777)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Peroxisomal matrix (GO:0005782)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Peroxisomal membrane (GO:0005778)	1	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Peroxisomal membrane (GO:0005778)	1	Experimental: experimental	Organelle	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.853	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.853	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.853	Unknown: inferred from electronic annotation	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

O60858

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase TRIM13

O95476

Interaction Score

O94901

(UniProtKB/Swiss-Prot/P) Details

SUN domain-containing protein 1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Intracellular membrane-bounded organelle (GO:0043231)	0.8	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nucleus (GO:0005634)	1	Experimental: experimental	eSLDB	PubMed
Nucleus	Nucleus (GO:0005634)	1	Predicted: pTarget method	LOCATE	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	Nuclear membrane (GO:0031965)	1	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Nucleus	Integral to nuclear inner membrane (GO:0005639)	1	Unknown: inferred from electronic annotation	GO	PubMed
Nucleus	Nuclear envelope (GO:0005635)	1	Experimental: inferred from direct assay	GO	PubMed
Nucleus	SUN-KASH complex (GO:0034993)	1	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Acrosomal membrane (GO:0002080)	0.3	Unknown: inferred from electronic annotation	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.8	Experimental: experimental	eSLDB	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

0.999

P01911

(UniProtKB/Swiss-Prot/P) Details

HLA class II histocompatibility antigen, DRB1-15 beta chain

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Membrane	Cell surface (GO:0009986)	0.994	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Integral to lumenal side of endoplasmic reticulum membrane (GO:0071556)	0.984	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Golgi membrane (GO:0000139)	0.984	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Trans-Golgi network membrane (GO:0032588)	0.984	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Late endosome membrane (GO:0031902)	0.984	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Lysosome (GO:0005764)	0.958	Predicted: PAML algorithm	PA-GOSUB	PubMed
Cytosol	Lysosomal membrane (GO:0005765)	0.958	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endocytic vesicle membrane (GO:0030666)	0.984	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	ER to Golgi transport vesicle membrane (GO:0012507)	0.984	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Clathrin-coated endocytic vesicle membrane (GO:0030669)	0.984	Unknown: traceable author statement	GO	PubMed
Secretory-pathway	Transport vesicle membrane (GO:0030658)	0.984	Unknown: traceable author statement	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Experimental: experimental	MatrixDB	PubMed
Extracellular	Extracellular region (GO:0005576)	0.94	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Membrane (GO:0016020)	0.994	Unknown: HDA	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.994	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Unknown: traceable author statement	GO	PubMed
Membrane	MHC class II protein complex (GO:0042613)	0.994	Experimental: inferred from direct assay	GO	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.958	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

0.999

Q9NXE4

(UniProtKB/Swiss-Prot/P) Details

Sphingomyelin phosphodiesterase 4

O95476

Interaction Score

0.999

Q9Y5M8

(UniProtKB/Swiss-Prot/P) Details

Signal recognition particle receptor subunit beta

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytoplasm (GO:0005737)	0.96	Experimental: inferred from direct assay	GO	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.987	Experimental: experimental	eSLDB	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.987	Predicted: PAML algorithm	PA-GOSUB	PubMed
Secretory-pathway	Signal recognition particle receptor complex (GO:0005785)	0.987	Predicted: inferred from biological aspect of ancestor	GO	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.987	Unknown: traceable author statement	GO	PubMed
Cytosol	Cytoplasmic microtubule (GO:0005881)	0.96	Experimental: inferred from direct assay	GO	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Membrane (GO:0016020)	0.994	Experimental: inferred from direct assay	GO	PubMed
Membrane	Integral to membrane (GO:0016021)	0.994	Experimental: experimental	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.994	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.994	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

0.999

Q9Y6I9

(UniProtKB/Swiss-Prot/P) Details

Testis-expressed protein 264

O95476

Interaction Score

0.999

P51648

(UniProtKB/Swiss-Prot/P) Details

Fatty aldehyde dehydrogenase

O95476

Interaction Score

0.999

O15173

(UniProtKB/Swiss-Prot/P) Details

Membrane-associated progesterone receptor component 2

O95476

Interaction Score

0.999

Q15904

(UniProtKB/Swiss-Prot/P) Details

V-type proton ATPase subunit S1

Localizations:

Major Localization	Minor Localization	Localization Score	Experiment Type	Source Database	PubMed ID
Cytosol	Cytosol (GO:0005829)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Secretory-pathway	Endoplasmic reticulum (GO:0005783)	0.931	Experimental: experimental	Human Proteinpedia	PubMed
Secretory-pathway	Endoplasmic reticulum membrane (GO:0005789)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endoplasmic reticulum-Golgi intermediate compartment membrane (GO:0033116)	0.931	Unknown: inferred from electronic annotation	GO	PubMed
Secretory-pathway	Endosome membrane (GO:0010008)	0.931	Unknown: traceable author statement	GO	PubMed
Cytosol	Microtubule cytoskeleton (GO:0015630)	0.972	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Extracellular	Extracellular region (GO:0005576)	0.8	Experimental: experimental	MatrixDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Predicted: SVM decision tree	eSLDB	PubMed
Membrane	Integral to membrane (GO:0016021)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Proton-transporting two-sector ATPase complex (GO:0016469)	0.999	Unknown: traceable author statement	GO	PubMed
Membrane	Proton-transporting two-sector ATPase complex (GO:0016469)	0.999	Experimental: experimental	Organelle	PubMed
Membrane	Proton-transporting V-type ATPase, V1 domain (GO:0033180)	0.999	Unknown: inferred from electronic annotation	GO	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Predicted: PAML algorithm	PA-GOSUB	PubMed
Membrane	Plasma membrane (GO:0005886)	0.999	Experimental: annotated protein expression (APE)	The Human Protein Atlas	PubMed
Cytosol	Extracellular vesicular exosome (GO:0070062)	0.972	Unknown: HDA	GO	PubMed

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed

O95476

Interaction Score

0.999

Q9HCE1

(UniProtKB/Swiss-Prot/P) Details

Putative helicase MOV-10

O95476

Interaction Score

0.999

Q9P0I2

(UniProtKB/Swiss-Prot/P) Details

ER membrane protein complex subunit 3

O95476

Interaction Score

0.998

O60602

(UniProtKB/Swiss-Prot/P) Details

Toll-like receptor 5

O95476

Interaction Score

0.998

Q8NEN9

(UniProtKB/Swiss-Prot/P) Details

PDZ domain-containing protein 8

O95476

Interaction Score

0.998

Q96A33

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil domain-containing protein 47

O95476

Interaction Score

0.998

Q6UXU6

(UniProtKB/Swiss-Prot/P) Details

Transmembrane protein 92

O95476

Interaction Score

0.998

Q6UXL0

(UniProtKB/Swiss-Prot/P) Details

Interleukin-20 receptor subunit beta

O95476

Interaction Score

0.993

Q9BUF5

(UniProtKB/Swiss-Prot/P) Details

Tubulin beta-6 chain

O95476

Interaction Score

0.992

Q8N766

(UniProtKB/Swiss-Prot/P) Details

ER membrane protein complex subunit 1

O95476

Interaction Score

0.99

A0A2R8Y7Z4

(UniProtKB/TrEmbl/P) Details

Toll-like receptor 5

O95476

Interaction Score

0.989

Q99618

(UniProtKB/Swiss-Prot/P) Details

Cell division cycle-associated protein 3

O95476

Interaction Score

0.989

Q9NX40

(UniProtKB/Swiss-Prot/P) Details

OCIA domain-containing protein 1

O95476

Interaction Score

0.986

Q59E96

(UniProtKB/TrEmbl/P) Details

Nuclear RNA export factor 1 variant

O95476

Interaction Score

0.983

P81408

(UniProtKB/Swiss-Prot/P) Details

Protein FAM189B

O95476

Interaction Score

0.981

Q8WV48

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil domain-containing protein 107

O95476

Interaction Score

0.969

Q96RL7

(UniProtKB/Swiss-Prot/P) Details

Vacuolar protein sorting-associated protein 13A

O95476

Interaction Score

0.968

A0A0C4DGX8

(UniProtKB/TrEmbl/P) Details

ATPase, H+ transporting, lysosomal accessory protein 1, isoform CRA_c

O95476

Interaction Score

0.967

H7BXF4

(UniProtKB/TrEmbl/P) Details

Sphingomyelin phosphodiesterase 4

O95476

Interaction Score

0.966

Q15884

(UniProtKB/Swiss-Prot/P) Details

Protein FAM189A2

O95476

Interaction Score

0.958

A0A087WTU3

(UniProtKB/TrEmbl/P) Details

Testis-expressed protein 264

O95476

Interaction Score

0.948

Q96CP6

(UniProtKB/Swiss-Prot/P) Details

GRAM domain-containing protein 1A

O95476

Interaction Score

0.947

P58658

(UniProtKB/Swiss-Prot/P) Details

Protein eva-1 homolog C

O95476

Interaction Score

0.947

Q6UX71

(UniProtKB/Swiss-Prot/P) Details

Plexin domain-containing protein 2

O95476

Interaction Score

0.946

Q9TQE0

(UniProtKB/Swiss-Prot/P) Details

HLA class II histocompatibility antigen, DRB1-9 beta chain

O95476

Interaction Score

0.943

B7Z2R7

(UniProtKB/TrEmbl/P) Details

Acyl-CoA-binding domain-containing protein 5

O95476

Interaction Score

0.941

P04229

(UniProtKB/Swiss-Prot/P) Details

HLA class II histocompatibility antigen, DRB1-1 beta chain

O95476

Interaction Score

0.941

P13761

(UniProtKB/Swiss-Prot/P) Details

HLA class II histocompatibility antigen, DRB1-7 beta chain

O95476

Interaction Score

0.941

Q29974

(UniProtKB/Swiss-Prot/P) Details

HLA class II histocompatibility antigen, DRB1-16 beta chain

O95476

Interaction Score

0.941

Q5Y7A7

(UniProtKB/Swiss-Prot/P) Details

HLA class II histocompatibility antigen, DRB1-13 beta chain

O95476

Interaction Score

0.938

Q5JR04

(UniProtKB/TrEmbl/P) Details

Mov10, Moloney leukemia virus 10, homolog (Mouse), isoform CRA_a

O95476

Interaction Score

0.938

J3KMY0

(UniProtKB/TrEmbl/P) Details

Cell division cycle-associated protein 3

O95476

Interaction Score

0.925

P01912

(UniProtKB/Swiss-Prot/P) Details

HLA class II histocompatibility antigen, DRB1-3 chain

O95476

Interaction Score

0.925

P20039

(UniProtKB/Swiss-Prot/P) Details

HLA class II histocompatibility antigen, DRB1-11 beta chain

O95476

Interaction Score

0.925

Q30134

(UniProtKB/Swiss-Prot/P) Details

HLA class II histocompatibility antigen, DRB1-8 beta chain

O95476

Interaction Score

0.925

Q30167

(UniProtKB/Swiss-Prot/P) Details

HLA class II histocompatibility antigen, DRB1-10 beta chain

O95476

Interaction Score

0.919

Q59H91

(UniProtKB/TrEmbl/P) Details

Inositol 1,4,5-trisphosphate receptor type 1 variant

O95476

Interaction Score

0.911

B4DSN5

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein phosphatase non-receptor type

O95476

Interaction Score

0.909

Q6MZP0

(UniProtKB/TrEmbl/P) Details

Uncharacterized protein DKFZp686M09200

O95476

Interaction Score

0.85

Q8WU02

(UniProtKB/TrEmbl/P) Details

C9orf61 protein

O95476

Interaction Score

0.847

M0QZ12

(UniProtKB/TrEmbl/P) Details

GRAM domain-containing protein 1A

O95476

Interaction Score

0.823

P37173

(UniProtKB/Swiss-Prot/P) Details

TGF-beta receptor type-2

O95476

Interaction Score

0.812

Q549N5

(UniProtKB/TrEmbl/P) Details

Signal recognition particle receptor beta subunit

O95476

Interaction Score

0.799

F5GX58

(UniProtKB/TrEmbl/P) Details

Cell division cycle-associated protein 3

O95476

Interaction Score

0.799

F8WDL1

(UniProtKB/TrEmbl/P) Details

Cell division cycle-associated protein 3

O95476

Interaction Score

0.79

K7EIS8

(UniProtKB/TrEmbl/P) Details

Noelin-2

O95476

Interaction Score

0.747

O00624

(UniProtKB/Swiss-Prot/P) Details

Sodium-dependent phosphate transport protein 3

O95476

Interaction Score

0.73

Q59ES2

(UniProtKB/TrEmbl/P) Details

Inositol 1,4,5-trisphosphate receptor type 3 variant

O95476

Interaction Score

0.726

Q59F04

(UniProtKB/TrEmbl/P) Details

Receptor protein-tyrosine kinase

O95476

Interaction Score

0.716

A3QNQ0

(UniProtKB/TrEmbl/P) Details

TGF-beta receptor type-2

O95476

Interaction Score

0.716

P13760

(UniProtKB/Swiss-Prot/P) Details

HLA class II histocompatibility antigen, DRB1-4 beta chain

O95476

Interaction Score

0.716

Q95IE3

(UniProtKB/Swiss-Prot/P) Details

HLA class II histocompatibility antigen, DRB1-12 beta chain

O95476

Interaction Score

0.716

Q9GIY3

(UniProtKB/Swiss-Prot/P) Details

HLA class II histocompatibility antigen, DRB1-14 beta chain

O95476

Interaction Score

0.699

A0A0A0MR12

(UniProtKB/TrEmbl/P) Details

Protein FAM189A2

O95476

Interaction Score

0.699

Q9Y6J7

(UniProtKB/TrEmbl/P) Details

Cote1

O95476

Interaction Score

0.64

D2JYI1

(UniProtKB/TrEmbl/P) Details

TGF-beta receptor type-2

O95476

Interaction Score

0.64

A8K3M3

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein phosphatase non-receptor type

O95476

Interaction Score

0.21

Q8NCM9

(UniProtKB/TrEmbl/P) Details

KIAA1996 protein

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O95476

Species

Number of Interactions

Average Interaction Score

Localizations:

First-Neighbour Network Visualization

Interactions

O95476

O00165

HCLS1-associated protein X-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95476

P63096

Guanine nucleotide-binding protein G(i) subunit alpha-1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95476

Q8WXH0

Nesprin-2

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95476

Q9NRG9

Aladin

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95476

Q14571

Inositol 1,4,5-trisphosphate receptor type 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95476

P16615

Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95476

Q9HC62

Sentrin-specific protease 2

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95476

Q14643

Inositol 1,4,5-trisphosphate receptor type 1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95476

Q9BTX1

Nucleoporin NDC1

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95476

P16435

NADPH--cytochrome P450 reductase

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95476

Q14573

Inositol 1,4,5-trisphosphate receptor type 3

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95476

Q9UHD9

Ubiquilin-2

Localizations:

Interaction Source Database:

Interaction Source Publication:

O95476