P01236

Prolactin    //   UniProt Profile 

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Species

 H. sapiens

Number of Interactions

 9 / 12

Average Interaction Score

 0.799

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.902 Experimental: experimental eSLDB PubMed 
Cytosol Cytosol (GO:0005829) 0.3 Unknown: unspecified method The Human Protein Atlas PubMed 
Secretory-pathway Endosome lumen (GO:0031904) 0.902 Unknown: traceable author statement GO PubMed 
Secretory-pathway Secretory granule (GO:0030141) 0.902 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.79 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.79 Predicted: pTarget method LOCATE PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

First-Neighbour Network Visualization

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The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

P01236

Interaction Score
0.992

P05538

(UniProtKB/Swiss-Prot/P) Details

HLA class II histocompatibility antigen, DQ beta 2 chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.983 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Integral to lumenal side of endoplasmic reticulum membrane (GO:0071556) 0.983 Unknown: traceable author statement GO PubMed 
Secretory-pathway Golgi membrane (GO:0000139) 0.983 Unknown: traceable author statement GO PubMed 
Secretory-pathway Trans-Golgi network membrane (GO:0032588) 0.983 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endosome membrane (GO:0010008) 0.983 Unknown: inferred from electronic annotation GO PubMed 
Cytosol Lysosomal membrane (GO:0005765) 0.3 Unknown: traceable author statement GO PubMed 
Secretory-pathway Endocytic vesicle membrane (GO:0030666) 0.983 Unknown: traceable author statement GO PubMed 
Secretory-pathway ER to Golgi transport vesicle membrane (GO:0012507) 0.983 Unknown: traceable author statement GO PubMed 
Secretory-pathway Clathrin-coated endocytic vesicle membrane (GO:0030669) 0.983 Unknown: traceable author statement GO PubMed 
Secretory-pathway Transport vesicle membrane (GO:0030658) 0.983 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.94 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Integral to membrane (GO:0016021) 0.853 Predicted: SVM decision tree eSLDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.853 Unknown: traceable author statement GO PubMed 
Membrane MHC class II protein complex (GO:0042613) 0.853 Unknown: non-traceable author statement GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P01236

Interaction Score
0.99

P28300

(UniProtKB/Swiss-Prot/P) Details

Protein-lysine 6-oxidase

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.96 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.96 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Extracellular Extracellular region (GO:0005576) 1 Experimental: experimental eSLDB PubMed 
Extracellular Extracellular region (GO:0005576) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 1 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 1 Experimental: experimental MatrixDB PubMed 
Extracellular Collagen (GO:0005581) 1 Unknown: inferred from electronic annotation GO PubMed 
Membrane Membrane (GO:0016020) 0.8 Experimental: experimental MatrixDB PubMed 

Interaction Source Database:

MatrixDB

Interaction Source Publication:

PubMed 

P01236

Interaction Score
0.986

P16471

(UniProtKB/Swiss-Prot/P) Details

Prolactin receptor

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Membrane Cell surface (GO:0009986) 0.999 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Endosome lumen (GO:0031904) 0.79 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Experimental: experimental MatrixDB PubMed 
Extracellular Extracellular region (GO:0005576) 0.958 Predicted: PAML algorithm PA-GOSUB PubMed 
Membrane Membrane (GO:0016020) 0.999 Experimental: experimental MatrixDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Experimental: experimental eSLDB PubMed 
Membrane Integral to membrane (GO:0016021) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Unknown: traceable author statement GO PubMed 
Membrane Plasma membrane (GO:0005886) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 

Interaction Source Database:

HPRD, DIP

Interaction Source Publication:

PubMed , PubMed 

P01236

Interaction Score
0.985

P13497

(UniProtKB/Swiss-Prot/P) Details

Bone morphogenetic protein 1

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.79 Predicted: SVM decision tree eSLDB PubMed 
Secretory-pathway Golgi apparatus (GO:0005794) 0.79 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.971 Unknown: traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.971 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.971 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular matrix (GO:0031012) 0.971 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.94 Experimental: experimental MatrixDB PubMed 
Membrane Plasma membrane (GO:0005886) 0.94 Predicted: pTarget method LOCATE PubMed 
Cytosol Vesicle (GO:0031982) 0.3 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

DIP, IntAct

Interaction Source Publication:

PubMed 

P01236

Interaction Score
0.985

P23284

(UniProtKB/Swiss-Prot/P) Details

Peptidyl-prolyl cis-trans isomerase B

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.972 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 0.972 Experimental: inferred from direct assay GO PubMed 
Mitochondrion Mitochondrion (GO:0005739) 0.7 Predicted: SVM decision tree eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Experimental: experimental Human Proteinpedia PubMed 
Nucleus Nucleus (GO:0005634) 0.998 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Macromolecular complex (GO:0032991) 0.998 Predicted: inferred from sequence or structural similarity GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.999 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.999 Experimental: experimental Organelle PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.999 Predicted: PAML algorithm PA-GOSUB PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.999 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Secretory-pathway Smooth endoplasmic reticulum (GO:0005790) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endoplasmic reticulum chaperone complex (GO:0034663) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Secretory-pathway Endoplasmic reticulum lumen (GO:0005788) 0.999 Unknown: non-traceable author statement GO PubMed 
Secretory-pathway Melanosome (GO:0042470) 0.999 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.51 Unknown: HDA GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 0.972 Unknown: HDA GO PubMed 
Membrane Focal adhesion (GO:0005925) 0.51 Unknown: HDA GO PubMed 

Interaction Source Database:

HPRD, BioGRID

Interaction Source Publication:

PubMed 

P01236

Interaction Score
0.905

Q9NRR5

(UniProtKB/Swiss-Prot/P) Details

Ubiquilin-4

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Cytosolic proteasome complex (GO:0031597) 1 Experimental: inferred from direct assay GO PubMed 
Cytosol Perinuclear region of cytoplasm (GO:0048471) 1 Unknown: inferred from electronic annotation GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: inferred from direct assay GO PubMed 
Nucleus Nucleus (GO:0005634) 1 Predicted: pTarget method LOCATE PubMed 
Nucleus Nucleus (GO:0005634) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Nucleus Nuclear proteasome complex (GO:0031595) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.958 Experimental: experimental eSLDB PubMed 
Secretory-pathway Endoplasmic reticulum membrane (GO:0005789) 0.958 Predicted: inferred from sequence or structural similarity GO PubMed 
Cytosol Autophagic vacuole (GO:0005776) 1 Experimental: inferred from direct assay GO PubMed 
Secretory-pathway Cytoplasmic vesicle (GO:0031410) 0.958 Unknown: inferred from electronic annotation GO PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P01236

Interaction Score
0.788

Q59F94

(UniProtKB/TrEmbl/P) Details

Ataxin-1 ubiquitin-like interacting protein variant

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 0.8 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Experimental: experimental eSLDB PubMed 
Nucleus Nucleus (GO:0005634) 0.94 Predicted: pTarget method LOCATE PubMed 
Secretory-pathway Endoplasmic reticulum (GO:0005783) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P01236

Interaction Score
0.56

Q5SR05

(UniProtKB/TrEmbl/P) Details

HLA class II histocompatibility antigen, DQ beta 2 chain

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Membrane Integral to membrane (GO:0016021) 0.7 Predicted: SVM decision tree eSLDB PubMed 

Interaction Source Database:

BioGRID

Interaction Source Publication:

PubMed 

P01236

Interaction Score
0

Q6FHY5

(UniProtKB/TrEmbl/P) Details

MEOX2 protein

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Nucleus Nucleus (GO:0005634) 0.8 Experimental: experimental eSLDB PubMed 

Interaction Source Database:

IntAct

Interaction Source Publication:

PubMed 

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ComPPI is published in Nucleic Acids Research Database Issue 2015