P02538

Keratin, type II cytoskeletal 6A    //   UniProt Profile 

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Species

H. sapiens

Number of Interactions

78 / 102

Average Interaction Score

0.903

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Cytosol Cytoplasm (GO:0005737) 1 Predicted: SVM decision tree eSLDB PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Experimental: experimental Human Proteinpedia PubMed 
Cytosol Cytoplasm (GO:0005737) 1 Predicted: PAML algorithm PA-GOSUB PubMed 
Cytosol Cytosol (GO:0005829) 1 Unknown: traceable author statement GO PubMed 
Nucleus Nucleus (GO:0005634) 0.3 Unknown: HDA GO PubMed 
Cytosol Cytoskeleton (GO:0005856) 1 Experimental: experimental Organelle PubMed 
Cytosol Intermediate filament cytoskeleton (GO:0045111) 1 Experimental: annotated protein expression (APE) The Human Protein Atlas PubMed 
Cytosol Keratin filament (GO:0045095) 1 Unknown: inferred from electronic annotation GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.8 Experimental: experimental MatrixDB PubMed 
Membrane Membrane (GO:0016020) 0.3 Unknown: HDA GO PubMed 
Cytosol Extracellular vesicular exosome (GO:0070062) 1 Unknown: HDA GO PubMed 

First-Neighbour Network Visualization

Toggle Display
Q15051Q9NQC7P15924Q9BT92P42566Q9H0R8O14964P36406Q14145O43765P60520P05783P08779P13646P08727P62993P37198Q04695Q9UHD9P22681Q15323P02545Q00005O43402Q13616Q9BVG8O76011Q92905Q9H0W5P19012P55040P61601Q93034P02768Q8N3L3P46108P19320P00533Q9BYV2Q9UBB9O76015P09651Q08379Q9Y3C0Q15834Q504Q3Q9UBS0Q96CW1Q8TF42Q92764Q7Z3Z0P29353Q7Z3Y7Q7Z3Y9Q7Z3Y8O75530Q6A162Q9BXB1Q13617P13612P01857Q12824O60341Q8NDF8R4GMQ1F5GWI9F5GZ97Q53Y03Q5TCI8Q14666A1A4E9A0A024R1I7G5E975Q9H836A0A0A0MTN0E9PFW3E9PJK2Q59ER8P02538

The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

P02538

Interaction Score
1

Q15051

(UniProtKB/Swiss-Prot/P) Details

IQ calmodulin-binding motif-containing protein 1

P02538

Interaction Score
1

Q9NQC7

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin carboxyl-terminal hydrolase CYLD

P02538

Interaction Score
1

P15924

(UniProtKB/Swiss-Prot/P) Details

Desmoplakin

P02538

Interaction Score
1

Q9BT92

(UniProtKB/Swiss-Prot/P) Details

Trichoplein keratin filament-binding protein

P02538

Interaction Score
1

P42566

(UniProtKB/Swiss-Prot/P) Details

Epidermal growth factor receptor substrate 15

P02538

Interaction Score
1

Q9H0R8

(UniProtKB/Swiss-Prot/P) Details

Gamma-aminobutyric acid receptor-associated protein-like 1

P02538

Interaction Score
1

O14964

(UniProtKB/Swiss-Prot/P) Details

Hepatocyte growth factor-regulated tyrosine kinase substrate

P02538

Interaction Score
1

P36406

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase TRIM23

P02538

Interaction Score
1

Q14145

(UniProtKB/Swiss-Prot/P) Details

Kelch-like ECH-associated protein 1

P02538

Interaction Score
1

O43765

(UniProtKB/Swiss-Prot/P) Details

Small glutamine-rich tetratricopeptide repeat-containing protein alpha

P02538

Interaction Score
1

P60520

(UniProtKB/Swiss-Prot/P) Details

Gamma-aminobutyric acid receptor-associated protein-like 2

P02538

Interaction Score
1

P05783

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cytoskeletal 18

P02538

Interaction Score
1

P08779

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cytoskeletal 16

P02538

Interaction Score
1

P13646

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cytoskeletal 13

P02538

Interaction Score
1

P08727

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cytoskeletal 19

P02538

Interaction Score
1

P62993

(UniProtKB/Swiss-Prot/P) Details

Growth factor receptor-bound protein 2

P02538

Interaction Score
1

P37198

(UniProtKB/Swiss-Prot/P) Details

Nuclear pore glycoprotein p62

P02538

Interaction Score
1

Q04695

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cytoskeletal 17

P02538

Interaction Score
1

Q9UHD9

(UniProtKB/Swiss-Prot/P) Details

Ubiquilin-2

P02538

Interaction Score
1

P22681

(UniProtKB/Swiss-Prot/P) Details

E3 ubiquitin-protein ligase CBL

P02538

Interaction Score
1

Q15323

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cuticular Ha1

P02538

Interaction Score
1

P02545

(UniProtKB/Swiss-Prot/P) Details

Prelamin-A/C

P02538

Interaction Score
1

Q00005

(UniProtKB/Swiss-Prot/P) Details

Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

P02538

Interaction Score
0.999

O43402

(UniProtKB/Swiss-Prot/P) Details

ER membrane protein complex subunit 8

P02538

Interaction Score
0.999

Q13616

(UniProtKB/Swiss-Prot/P) Details

Cullin-1

P02538

Interaction Score
0.999

Q9BVG8

(UniProtKB/Swiss-Prot/P) Details

Kinesin-like protein KIFC3

P02538

Interaction Score
0.999

O76011

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cuticular Ha4

P02538

Interaction Score
0.999

Q92905

(UniProtKB/Swiss-Prot/P) Details

COP9 signalosome complex subunit 5

P02538

Interaction Score
0.999

Q9H0W5

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil domain-containing protein 8

P02538

Interaction Score
0.999

P19012

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cytoskeletal 15

P02538

Interaction Score
0.998

P55040

(UniProtKB/Swiss-Prot/P) Details

GTP-binding protein GEM

P02538

Interaction Score
0.998

P61601

(UniProtKB/Swiss-Prot/P) Details

Neurocalcin-delta

P02538

Interaction Score
0.998

Q93034

(UniProtKB/Swiss-Prot/P) Details

Cullin-5

P02538

Interaction Score
0.997

P02768

(UniProtKB/Swiss-Prot/P) Details

Serum albumin

P02538

Interaction Score
0.996

Q8N3L3

(UniProtKB/Swiss-Prot/P) Details

Beta-taxilin

P02538

Interaction Score
0.996

P46108

(UniProtKB/Swiss-Prot/P) Details

Adapter molecule crk

P02538

Interaction Score
0.996

P19320

(UniProtKB/Swiss-Prot/P) Details

Vascular cell adhesion protein 1

P02538

Interaction Score
0.996

P00533

(UniProtKB/Swiss-Prot/P) Details

Epidermal growth factor receptor

P02538

Interaction Score
0.995

Q9BYV2

(UniProtKB/Swiss-Prot/P) Details

Tripartite motif-containing protein 54

P02538

Interaction Score
0.994

Q9UBB9

(UniProtKB/Swiss-Prot/P) Details

Tuftelin-interacting protein 11

P02538

Interaction Score
0.994

O76015

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cuticular Ha8

P02538

Interaction Score
0.994

P09651

(UniProtKB/Swiss-Prot/P) Details

Heterogeneous nuclear ribonucleoprotein A1

P02538

Interaction Score
0.991

Q08379

(UniProtKB/Swiss-Prot/P) Details

Golgin subfamily A member 2

P02538

Interaction Score
0.99

Q9Y3C0

(UniProtKB/Swiss-Prot/P) Details

WASH complex subunit 3

P02538

Interaction Score
0.99

Q15834

(UniProtKB/Swiss-Prot/P) Details

Coiled-coil domain-containing protein 85B

P02538

Interaction Score
0.988

Q504Q3

(UniProtKB/Swiss-Prot/P) Details

PAN2-PAN3 deadenylation complex catalytic subunit PAN2

P02538

Interaction Score
0.987

Q9UBS0

(UniProtKB/Swiss-Prot/P) Details

Ribosomal protein S6 kinase beta-2

P02538

Interaction Score
0.985

Q96CW1

(UniProtKB/Swiss-Prot/P) Details

AP-2 complex subunit mu

P02538

Interaction Score
0.985

Q8TF42

(UniProtKB/Swiss-Prot/P) Details

Ubiquitin-associated and SH3 domain-containing protein B

P02538

Interaction Score
0.982

Q92764

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cuticular Ha5

P02538

Interaction Score
0.979

Q7Z3Z0

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cytoskeletal 25

P02538

Interaction Score
0.978

P29353

(UniProtKB/Swiss-Prot/P) Details

SHC-transforming protein 1

P02538

Interaction Score
0.976

Q7Z3Y7

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cytoskeletal 28

P02538

Interaction Score
0.969

Q7Z3Y9

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cytoskeletal 26

P02538

Interaction Score
0.969

Q7Z3Y8

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cytoskeletal 27

P02538

Interaction Score
0.958

O75530

(UniProtKB/Swiss-Prot/P) Details

Polycomb protein EED

P02538

Interaction Score
0.956

Q6A162

(UniProtKB/Swiss-Prot/P) Details

Keratin, type I cytoskeletal 40

P02538

Interaction Score
0.949

Q9BXB1

(UniProtKB/Swiss-Prot/P) Details

Leucine-rich repeat-containing G-protein coupled receptor 4

P02538

Interaction Score
0.931

Q13617

(UniProtKB/Swiss-Prot/P) Details

Cullin-2

P02538

Interaction Score
0.915

P13612

(UniProtKB/Swiss-Prot/P) Details

Integrin alpha-4

P02538

Interaction Score
0.874

P01857

(UniProtKB/Swiss-Prot/P) Details

Immunoglobulin heavy constant gamma 1

P02538

Interaction Score
0.86

Q12824

(UniProtKB/Swiss-Prot/P) Details

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

P02538

Interaction Score
0.86

O60341

(UniProtKB/Swiss-Prot/P) Details

Lysine-specific histone demethylase 1A

P02538

Interaction Score
0.859

Q8NDF8

(UniProtKB/Swiss-Prot/P) Details

Non-canonical poly(A) RNA polymerase PAPD5

P02538

Interaction Score
0.848

R4GMQ1

(UniProtKB/TrEmbl/P) Details

Lysine-specific histone demethylase 1A

P02538

Interaction Score
0.8

F5GWI9

(UniProtKB/TrEmbl/P) Details

WASH complex subunit 3

P02538

Interaction Score
0.8

F5GZ97

(UniProtKB/TrEmbl/P) Details

WASH complex subunit 3

P02538

Interaction Score
0.772

Q53Y03

(UniProtKB/TrEmbl/P) Details

COX4 neighbor, isoform CRA_a

P02538

Interaction Score
0.763

Q5TCI8

(UniProtKB/TrEmbl/P) Details

Prelamin-A/C

P02538

Interaction Score
0.7

Q14666

(UniProtKB/TrEmbl/P) Details

Radiated keratinocyte mRNA 266

P02538

Interaction Score
0.7

A1A4E9

(UniProtKB/TrEmbl/P) Details

Keratin 13, isoform CRA_a

P02538

Interaction Score
0.64

A0A024R1I7

(UniProtKB/TrEmbl/P) Details

Tuftelin-interacting protein 11

P02538

Interaction Score
0.296

G5E975

(UniProtKB/TrEmbl/P) Details

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1, isoform CRA_c

P02538

Interaction Score
0.292

Q9H836

(UniProtKB/TrEmbl/P) Details

cDNA FLJ13963 fis, clone Y79AA1001299, highly similar to Homo sapiens integrase interactor 1b protein

P02538

Interaction Score
0.24

A0A0A0MTN0

(UniProtKB/TrEmbl/P) Details

Cullin-2

P02538

Interaction Score
0.24

E9PFW3

(UniProtKB/TrEmbl/P) Details

AP-2 complex subunit mu

P02538

Interaction Score
0.24

E9PJK2

(UniProtKB/TrEmbl/P) Details

Polycomb protein EED

P02538

Interaction Score
0.21

Q59ER8

(UniProtKB/TrEmbl/P) Details

Leucine-rich repeat-containing G protein-coupled receptor 4 variant

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ComPPI is published in Nucleic Acids Research Database Issue 2015