P05019

Insulin-like growth factor I    //   UniProt Profile 

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Species

H. sapiens

Number of Interactions

22 / 28

Average Interaction Score

0.804

Localizations:

Major Localization Minor Localization Localization Score Experiment Type Source Database PubMed ID
Secretory-pathway Secretory pathway (GO:secretory_pathway) 0.958 Experimental: experimental eSLDB PubMed 
Secretory-pathway Platelet alpha granule lumen (GO:0031093) 0.958 Unknown: traceable author statement GO PubMed 
Secretory-pathway Exocytic vesicle (GO:0070382) 0.958 Predicted: inferred from sequence or structural similarity GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.998 Unknown: non-traceable author statement GO PubMed 
Extracellular Extracellular region (GO:0005576) 0.998 Predicted: pTarget method LOCATE PubMed 
Extracellular Extracellular region (GO:0005576) 0.998 Predicted: PAML algorithm PA-GOSUB PubMed 
Extracellular Extracellular space (GO:0005615) 0.998 Experimental: inferred from direct assay GO PubMed 
Extracellular Insulin-like growth factor binding protein complex (GO:0016942) 0.998 Unknown: inferred by curator GO PubMed 
Extracellular Insulin-like growth factor ternary complex (GO:0042567) 0.998 Experimental: inferred from direct assay GO PubMed 
Membrane Membrane (GO:0016020) 0.96 Experimental: experimental MatrixDB PubMed 
Membrane Alphav-beta3 integrin-IGF-1-IGF1R complex (GO:0035867) 0.96 Experimental: inferred from direct assay GO PubMed 

First-Neighbour Network Visualization

Toggle Display
P18065P02787P17936P48745P24593P08833P35858P22692Q16270Q8N6C5P14735P06213P08069Q8TAY0P14866C9J5X1C9JMY1A0PJA6Q06AH7Q6NTA2Q06945Q01094P05019

The first-neighbour network shows the interaction map after the filtration (if there was any).
Edge-widths are proportional to the respective Interaction Score.


Interactions

All Details

P05019

Interaction Score
1

P18065

(UniProtKB/Swiss-Prot/P) Details

Insulin-like growth factor-binding protein 2

P05019

Interaction Score
1

P02787

(UniProtKB/Swiss-Prot/P) Details

Serotransferrin

P05019

Interaction Score
1

P17936

(UniProtKB/Swiss-Prot/P) Details

Insulin-like growth factor-binding protein 3

P05019

Interaction Score
1

P48745

(UniProtKB/Swiss-Prot/P) Details

Protein NOV homolog

P05019

Interaction Score
1

P24593

(UniProtKB/Swiss-Prot/P) Details

Insulin-like growth factor-binding protein 5

P05019

Interaction Score
1

P08833

(UniProtKB/Swiss-Prot/P) Details

Insulin-like growth factor-binding protein 1

P05019

Interaction Score
1

P35858

(UniProtKB/Swiss-Prot/P) Details

Insulin-like growth factor-binding protein complex acid labile subunit

P05019

Interaction Score
1

P22692

(UniProtKB/Swiss-Prot/P) Details

Insulin-like growth factor-binding protein 4

P05019

Interaction Score
0.999

Q16270

(UniProtKB/Swiss-Prot/P) Details

Insulin-like growth factor-binding protein 7

P05019

Interaction Score
0.998

Q8N6C5

(UniProtKB/Swiss-Prot/P) Details

Immunoglobulin superfamily member 1

P05019

Interaction Score
0.997

P14735

(UniProtKB/Swiss-Prot/P) Details

Insulin-degrading enzyme

P05019

Interaction Score
0.994

P06213

(UniProtKB/Swiss-Prot/P) Details

Insulin receptor

P05019

Interaction Score
0.992

P08069

(UniProtKB/Swiss-Prot/P) Details

Insulin-like growth factor 1 receptor

P05019

Interaction Score
0.953

Q8TAY0

(UniProtKB/TrEmbl/P) Details

Insulin-like growth factor binding protein, acid labile subunit

P05019

Interaction Score
0.857

P14866

(UniProtKB/Swiss-Prot/P) Details

Heterogeneous nuclear ribonucleoprotein L

P05019

Interaction Score
0.799

C9J5X1

(UniProtKB/TrEmbl/P) Details

Tyrosine-protein kinase receptor

P05019

Interaction Score
0.766

C9JMY1

(UniProtKB/TrEmbl/P) Details

Insulin-like growth factor-binding protein 2

P05019

Interaction Score
0.671

A0PJA6

(UniProtKB/TrEmbl/P) Details

TF protein

P05019

Interaction Score
0.671

Q06AH7

(UniProtKB/TrEmbl/P) Details

Transferrin

P05019

Interaction Score
0

Q6NTA2

(UniProtKB/TrEmbl/P) Details

HNRNPL protein

P05019

Interaction Score
0

Q06945

(UniProtKB/Swiss-Prot/P) Details

Transcription factor SOX-4

P05019

Interaction Score
0

Q01094

(UniProtKB/Swiss-Prot/P) Details

Transcription factor E2F1

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ComPPI is published in Nucleic Acids Research Database Issue 2015